Search Results - "Bohm, Michael"

Heart rate: from heart failure to chronic diseases and cancer. Is there a role for supportive care by heart rate reduction? by Böhm, Michael

Get full text

Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study by Krum, Henry, Prof, Schlaich, Markus P, Prof, Sobotka, Paul A, Prof, Böhm, Michael, MD, Mahfoud, Felix, MD, Rocha-Singh, Krishna, MD, Katholi, Richard, MD, Esler, Murray D, Prof

“…Summary Background Renal denervation (RDN) with radiofrequency ablation substantially reduces blood pressure in patients with treatment-resistant hypertension…”
Get full text

Impact of Lesion Placement on Efficacy and Safety of Catheter-Based Radiofrequency Renal Denervation by Mahfoud, Felix, MD, Tunev, Stefan, DVM, Ewen, Sebastian, MD, Cremers, Bodo, MD, Ruwart, Jennifer, BS, Schulz-Jander, Daniel, PhD, Linz, Dominik, MD, PhD, Davies, Justin, MD, PhD, Kandzari, David E., MD, PhD, Whitbourn, Robert, MD, Böhm, Michael, MD, Melder, Robert J., ScD

“…Abstract Background Insufficient procedural efficacy has been proposed to explain nonresponse to renal denervation (RDN). Objectives The aim of this study was…”
Get full text

Effect of ivabradine in patients with heart failure with preserved ejection fraction: the EDIFY randomized placebo‐controlled trial by Komajda, Michel, Isnard, Richard, Cohen‐Solal, Alain, Metra, Marco, Pieske, Burkert, Ponikowski, Piotr, Voors, Adriaan A., Dominjon, Fabienne, Henon‐Goburdhun, Cécile, Pannaux, Matthieu, Böhm, Michael

“…Aims This randomized, double‐blind, placebo‐controlled trial assessed whether heart rate (HR) reduction with ivabradine improves cardiac function in heart…”
Get full text

The SPYRAL HTN Global Clinical Trial Program: Rationale and design for studies of renal denervation in the absence (SPYRAL HTN OFF-MED) and presence (SPYRAL HTN ON-MED) of antihypertensive medications by Kandzari, David E., MD, Kario, Kazuomi, MD, Mahfoud, Felix, MD, Cohen, Sidney A., MD, PhD, Pilcher, Garrett, MS, Pocock, Stuart, PhD, Townsend, Raymond, MD, Weber, Michael A., MD, Böhm, Michael, MD

“…Renal sympathetic activation plays a key role in the pathogenesis of hypertension, as demonstrated by high renal norepinephrine spillover into plasma of…”
Get full text

Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study by Swedberg, Karl, Prof, Komajda, Michel, Prof, Böhm, Michael, Prof, Borer, Jeffrey S, Prof, Ford, Ian, Prof, Dubost-Brama, Ariane, MD, Lerebours, Guy, MD, Tavazzi, Luigi, Prof

“…Summary Background Chronic heart failure is associated with high mortality and morbidity. Raised resting heart rate is a risk factor for adverse outcomes. We…”
Get full text

Effect of Ferric Carboxymaltose on Exercise Capacity in Patients With Chronic Heart Failure and Iron Deficiency by van Veldhuisen, Dirk J, Ponikowski, Piotr, van der Meer, Peter, Metra, Marco, Böhm, Michael, Doletsky, Artem, Voors, Adriaan A, Macdougall, Iain C, Anker, Stefan D, Roubert, Bernard, Zakin, Lorraine, Cohen-Solal, Alain

“…BACKGROUND:Iron deficiency is common in patients with heart failure (HF) and is associated with reduced exercise capacity and poor outcomes. Whether correction…”
Get full text

Top earnings inequality and the gender pay gap: Canada, Sweden, and the United Kingdom by Fortin, Nicole M., Bell, Brian, Böhm, Michael

“…This paper explores the consequences of the under-representation of women in top jobs for the overall gender pay gap. Using administrative annual earnings data…”
Get full text

A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease by Filippatos, Gerasimos, Anker, Stefan D, Böhm, Michael, Gheorghiade, Mihai, Køber, Lars, Krum, Henry, Maggioni, Aldo P, Ponikowski, Piotr, Voors, Adriaan A, Zannad, Faiez, Kim, So-Young, Nowack, Christina, Palombo, Giovanni, Kolkhof, Peter, Kimmeskamp-Kirschbaum, Nina, Pieper, Alexander, Pitt, Bertram

“…To evaluate oral doses of the non-steroidal mineralocorticoid receptor antagonist finerenone given for 90 days in patients with worsening heart failure and…”
Get full text

Empagliflozin, Health Status, and Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The EMPEROR-Preserved Trial by Butler, Javed, Filippatos, Gerasimos, Jamal Siddiqi, Tariq, Brueckmann, Martina, Böhm, Michael, Chopra, Vijay K., Pedro Ferreira, João, Januzzi, James L., Kaul, Sanjay, Piña, Ileana L., Ponikowski, Piotr, Shah, Sanjiv J., Senni, Michele, Vedin, Ola, Verma, Subodh, Peil, Barbara, Pocock, Stuart J., Zannad, Faiez, Packer, Milton, Anker, Stefan D.

“…Patients with heart failure with preserved ejection fraction have significant impairment in health-related quality of life. In the EMPEROR-Preserved trial…”
Get full text

Targeting Mitochondrial Oxidative Stress in Heart Failure: Throttling the Afterburner by Maack, Christoph, Böhm, Michael

“…Considering the second scenario, activity of Mn-SOD is reduced in heart failure, and although glutathione peroxidase activity was unchanged in homogenized…”
Get full text

Treatment of Coronary In-Stent Restenosis with a Paclitaxel-Coated Balloon Catheter by Scheller, Bruno, Hehrlein, Christoph, Bocksch, Wolfgang, Rutsch, Wolfgang, Haghi, Dariush, Dietz, Ulrich, Böhm, Michael, Speck, Ulrich

“…In a pilot trial, 52 patients with coronary disease and restenosis of a previously placed intracoronary stent underwent angioplasty with either a…”
Get full text

Use of fixed-dose combination antihypertensives in Germany between 2016 and 2020: an example of guideline inertia by Mahfoud, Felix, Kieble, Marita, Enners, Salka, Kintscher, Ulrich, Laufs, Ulrich, Böhm, Michael, Schulz, Martin

“…Background The 2018 European Society of Cardiology (ESC)/European Society of Hypertension (ESH) guidelines for the management of hypertension highlight the…”
Get full text

Predictors of Outcome in Patients With Suspected Myocarditis by KINDERMANN, Ingrid, KINDERMANN, Michael, KANDOLF, Reinhard, KLINGEL, Karin, BÜLTMANN, Burkhard, MÜLLER, Thomas, LINDINGER, Angelika, BÖHM, Michael

“…The objective of this study was to identify the prognostic indicators in patients with suspected myocarditis who underwent endomyocardial biopsy. Between 1994…”
Get full text

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial by Esler, Murray D, Böhm, Michael, Sievert, Horst, Rump, Christian L, Schmieder, Roland E, Krum, Henry, Mahfoud, Felix, Schlaich, Markus P

“…The aim of this study was to determine long-term results of renal artery denervation for treatment of treatment-resistant hypertension in the SYMPLICITY HTN-2…”
Get full text

Efficacy of Dapagliflozin on Renal Function and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction: Results of DAPA-HF by Jhund, Pardeep S., Solomon, Scott D., Docherty, Kieran F., Heerspink, Hiddo J.L., Anand, Inder S., Böhm, Michael, Chopra, Vijay, de Boer, Rudolf A., Desai, Akshay S., Ge, Junbo, Kitakaze, Masafumi, Merkley, Bela, O'Meara, Eileen, Shou, Morten, Tereshchenko, Sergey, Verma, Subodh, Vinh, Pham Nguyen, Inzucchi, Silvio E., Køber, Lars, Kosiborod, Mikhail N., Martinez, Felipe A., Ponikowski, Piotr, Sabatine, Marc S., Bengtsson, Olof, Langkilde, Anna Maria, Sjöstrand, Mikaela, McMurray, John J.V.

“…Many patients with heart failure and reduced ejection fraction (HFrEF) have chronic kidney disease that complicates pharmacological management and is…”
Get full text

Circulating Endothelial Progenitor Cells and Cardiovascular Outcomes by Werner, Nikos, Kosiol, Sonja, Schiegl, Tobias, Ahlers, Patrick, Walenta, Katrin, Link, Andreas, Böhm, Michael, Nickenig, Georg

“…Circulating endothelial progenitor cells are derived from the bone marrow and are believed to support the integrity of the vascular endothelium. In this study…”
Get full text

The 2018 ESC/ESH Guidelines for the management of arterial hypertension: A German point of view by Emrich, Insa E, Böhm, Michael, Mahfoud, Felix

Get full text

Cardiovascular Risk Reduction After Renal Denervation According to Time in Therapeutic Systolic Blood Pressure Range by Mahfoud, Felix, Mancia, Giuseppe, Schmieder, Roland E., Ruilope, Luis, Narkiewicz, Krzysztof, Schlaich, Markus, Williams, Bryan, Ribichini, Flavio, Weil, Joachim, Kao, Hsien-Li, Rodriguez-Leor, Oriol, Noory, Elias, Ong, Tiong Kiam, Unterseeh, Thierry, de Araújo Gonçalves, Pedro, Zirlik, Andreas, Almerri, Khaled, Sharif, Faisal, Lauder, Lucas, Wanten, Marianne, Fahy, Martin, Böhm, Michael

“…Renal denervation (RDN) has been shown to lower blood pressure (BP), but its effects on cardiovascular events have only been preliminarily evaluated. Time in…”
Get full text

HDAC4 controls histone methylation in response to elevated cardiac load by Hohl, Mathias, Wagner, Michael, Reil, Jan-Christian, Müller, Sarah-Anne, Tauchnitz, Marcus, Zimmer, Angela M, Lehmann, Lorenz H, Thiel, Gerald, Böhm, Michael, Backs, Johannes, Maack, Christoph

“…In patients with heart failure, reactivation of a fetal gene program, including atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), is a…”
Get full text