Search Results - "Bohlen, T. T."

A Monte Carlo-based treatment planning tool for proton therapy by Mairani, A, Böhlen, T T, Schiavi, A, Tessonnier, T, Molinelli, S, Brons, S, Battistoni, G, Parodi, K, Patera, V

“…In the field of radiotherapy, Monte Carlo (MC) particle transport calculations are recognized for their superior accuracy in predicting dose and fluence…”
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On the influence of model parametrization in elastic full waveform tomography by Köhn, D., De Nil, D., Kurzmann, A., Przebindowska, A., Bohlen, T.

“…SUMMARY Elastic Full Waveform Tomography (FWT) aims to reduce the misfit between recorded and modelled data, to deduce a very detailed model of elastic…”
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Benchmarking nuclear models of FLUKA and GEANT4 for carbon ion therapy by Böhlen, T T, Cerutti, F, Dosanjh, M, Ferrari, A, Gudowska, I, Mairani, A, Quesada, J M

“…As carbon ions, at therapeutic energies, penetrate tissue, they undergo inelastic nuclear reactions and give rise to significant yields of secondary fragment…”
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FLUKA particle therapy tool for Monte Carlo independent calculation of scanned proton and carbon ion beam therapy by Kozłowska, Wioletta S, Böhlen, Till T, Cuccagna, Caterina, Ferrari, Alfredo, Fracchiolla, Francesco, Magro, Giuseppe, Mairani, Andrea, Schwarz, Marco, Vlachoudis, Vasilis, Georg, Dietmar

“…While Monte Carlo (MC) codes are considered as the gold standard for dosimetric calculations, the availability of user friendly MC codes suited for particle…”
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A phenomenological relative biological effectiveness approach for proton therapy based on an improved description of the mixed radiation field by Mairani, A, Dokic, I, Magro, G, Tessonnier, T, Bauer, J, Böhlen, T T, Ciocca, M, Ferrari, A, Sala, P R, Jäkel, O, Debus, J, Haberer, T, Abdollahi, A, Parodi, K

“…Proton therapy treatment planning systems (TPSs) are based on the assumption of a constant relative biological effectiveness (RBE) of 1.1 without taking into…”
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Dose- and Volume-Limiting Late Toxicity of FLASH Radiotherapy in Cats with Squamous Cell Carcinoma of the Nasal Planum and in Mini Pigs by Rohrer Bley, Carla, Wolf, Friederike, Gonçalves Jorge, Patrik, Grilj, Veljko, Petridis, Ioannis, Petit, Benoit, Böhlen, Till T, Moeckli, Raphael, Limoli, Charles, Bourhis, Jean, Meier, Valeria, Vozenin, Marie-Catherine

“…The FLASH effect is characterized by normal tissue sparing without compromising tumor control. Although demonstrated in various preclinical models, safe…”
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A Monte Carlo-based treatment-planning tool for ion beam therapy by Böhlen, T.T., Bauer, J., Dosanjh, M., Ferrari, A., Haberer, T., Parodi, K., Patera, V., Mairani, A.

“…Ion beam therapy, as an emerging radiation therapy modality, requires continuous efforts to develop and improve tools for patient treatment planning (TP) and…”
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Biologically optimized helium ion plans: calculation approach and its in vitro validation by Mairani, A, Dokic, I, Magro, G, Tessonnier, T, Kamp, F, Carlson, D J, Ciocca, M, Cerutti, F, Sala, P R, Ferrari, A, Böhlen, T T, Jäkel, O, Parodi, K, Debus, J, Abdollahi, A, Haberer, T

“…Treatment planning studies on the biological effect of raster-scanned helium ion beams should be performed, together with their experimental verification,…”
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3-D multicomponent full waveform inversion for shallow-seismic target: Ettlingen Line case study by Irnaka, T M, Brossier, R, Métivier, L, Bohlen, T, Pan, Y

“…SUMMARY In this work, we investigate methodological development and application of viscoelastic full waveform inversion to a multicomponent source and receiver…”
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3D elastic full-waveform inversion of small-scale heterogeneities in transmission geometry by Butzer, S., Kurzmann, A., Bohlen, T.

“…ABSTRACT Three‐dimensional elastic full‐waveform inversion aims to reconstruct elastic material properties of 3D structures in the subsurface with high…”
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Commissioning and quality assurance of a novel solution for respiratory-gated PBS proton therapy based on optical tracking of surface markers by Fattori, Giovanni, Hrbacek, Jan, Regele, Harald, Bula, Christian, Mayor, Alexandre, Danuser, Stefan, Oxley, David C., Rechsteiner, Urs, Grossmann, Martin, Via, Riccardo, Böhlen, Till T., Bolsi, Alessandra, Walser, Marc, Togno, Michele, Colvill, Emma, Lempen, Daniel, Weber, Damien C., Lomax, Antony J., Safai, Sairos

“…We present the commissioning and quality assurance of our clinical protocol for respiratory gating in pencil beam scanning proton therapy for cancer patients…”
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FLUKA simulations of the response of tissue-equivalent proportional counters to ion beams for applications in hadron therapy and space by Böhlen, T T, Dosanjh, M, Ferrari, A, Gudowska, I, Mairani, A

“…For both cancer therapy with protons and ions (hadron therapy) and space radiation environments, the spatial energy deposition patterns of the radiation fields…”
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Simulations of microdosimetric quantities with the Monte Carlo code FLUKA for carbon ions at therapeutic energies by Böhlen, Till T., Dosanjh, Manjit, Ferrari, Alfredo, Gudowska, Irena

“…Abstract Purpose: Microdosimetric quantities can be used to estimate the biological effectiveness of radiation fields. This study evaluates the capability of…”
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Dosimetric verification in water of a Monte Carlo treatment planning tool for proton, helium, carbon and oxygen ion beams at the Heidelberg Ion Beam Therapy Center by Tessonnier, T, Böhlen, T T, Ceruti, F, Ferrari, A, Sala, P, Brons, S, Haberer, T, Debus, J, Parodi, K, Mairani, A

“…The introduction of 'new' ion species in particle therapy needs to be supported by a thorough assessment of their dosimetric properties and by treatment…”
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Seismic Velocities and Anisotropy of the Lower Continental Crust: A Review by Weiss, T, Siegesmund, S, Rabbel, W, Bohlen, T, Pohl, M

“…--Seismic anisotropy is often neglected in seismic studies of the earth's crust. Since anisotropy is a common property of many typically deep crustal rocks,…”
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Distributions of secondary particles in proton and carbon-ion therapy: a comparison between GATE/Geant4 and FLUKA Monte Carlo codes by Robert, C, Dedes, G, Battistoni, G, Böhlen, T T, Buvat, I, Cerutti, F, Chin, M P W, Ferrari, A, Gueth, P, Kurz, C, Lestand, L, Mairani, A, Montarou, G, Nicolini, R, Ortega, P G, Parodi, K, Prezado, Y, Sala, P R, Sarrut, D, Testa, E

“…Monte Carlo simulations play a crucial role for in-vivo treatment monitoring based on PET and prompt gamma imaging in proton and carbon-ion therapies. The…”
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Superdeep vertical seismic profiling at the KTB deep drill hole (Germany): Seismic close-up view of a major thrust zone down to 8.5 km depth by Rabbel, W., Beilecke, T., Bohlen, T., Fischer, D., Frank, A., Hasenclever, J., Borm, G., Kück, J., Bram, K., Druivenga, G., Lüschen, E., Gebrande, H., Pujol, J., Smithson, S.

“…The lowermost section of the continental superdeep drill hole German Continental Deep Drilling Program (KTB) (south Germany) has been investigated for the…”
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Investigating the robustness of ion beam therapy treatment plans to uncertainties in biological treatment parameters by Böhlen, T T, Brons, S, Dosanjh, M, Ferrari, A, Fossati, P, Haberer, T, Patera, V, Mairani, A

“…Uncertainties in determining clinically used relative biological effectiveness (RBE) values for ion beam therapy carry the risk of absolute and relative…”
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The FLUKA Code: Developments and Challenges for High Energy and Medical Applications by Böhlen, T.T., Cerutti, F., Chin, M.P.W., Fassò, A., Ferrari, A., Ortega, P.G., Mairani, A., Sala, P.R., Smirnov, G., Vlachoudis, V.

“…The FLUKA Monte Carlo code is used extensively at CERN for all beam-machine interactions, radioprotection calculations and facility design of forthcoming…”
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A joint physics and radiobiology DREAM team vision – Towards better response prediction models to advance radiotherapy by Vens, C., van Luijk, P., Vogelius, R.I., El Naqa, I., Humbert-Vidan, L., von Neubeck, C., Gomez-Roman, N., Bahn, E., Brualla, L., Böhlen, T.T., Ecker, S., Koch, R., Handeland, A., Pereira, S., Possenti, L., Rancati, T., Todor, D., Vanderstraeten, B., Van Heerden, M., Ullrich, W., Jackson, M., Alber, M., Marignol, L.

“…•Optimal RT outcomes requires accurate robust predictive radiation oncology models.•Present challenges in model and data quality must be addressed to improve…”
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