Search Results - "Bohdan, A."

Revisit of Nonlinear Landau Damping for Electrostatic Instability Driven by Blazar-induced Pair Beams by Vafin, S., Deka, P. J., Pohl, M., Bohdan, A.

“…We revisit the effect of nonlinear Landau (NL) damping on the electrostatic instability of blazar-induced pair beams, using a realistic pair-beam distribution…”
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Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives by Chalyk, Bohdan A., Zginnyk, Oleksandr, Khutorianskyi, Andrii V., Mykhailiuk, Pavel K.

“…Electron-rich, electron-deficient, and non-activated alkenes can be rapidly functionalized by in situ-generated difluoromethyl nitrile oxide. The (3+2)…”
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Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery by Chalyk, Bohdan A., Butko, Maryna V., Yanshyna, Oksana O., Gavrilenko, Konstantin S., Druzhenko, Tetiana V., Mykhailiuk, Pavel K.

“…In the context of drug discovery, novel spirocyclic pyrrolidines have been synthesized in two steps from common three‐ to seven‐membered‐ring (hetero)alicyclic…”
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Synthesis of Spirocyclic and Fused Isoxazoline Building Blocks by Chalyk, Bohdan A., Izhyk, Vitalii V., Danyleiko, Kyrylo, Sosunovych, Bohdan, Vashchenko, Bohdan V., Zginnyk, Oleksandr, Olshanska, Violetta, Teodorovic, Peter, Biitseva, Angelina V., Volochnyuk, Dmitriy M., Grygorenko, Oleksandr O.

“…A highly efficient multigram synthesis of spirocyclic and fused isoxazoline building blocks is described. Isoxazoline‐3‐carboxylates were synthesized via a…”
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Erratum: "Revisit of Nonlinear Landau Damping for Electrostatic Instability Driven by Blazar-induced Pair Beams" (2019, ApJ, 873, 10) by Deka, P. J., Pohl, M., Vafin, S., Bohdan, A.

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Synthesis of 5‑(Fluoroalkyl)isoxazole Building Blocks by Regioselective Reactions of Functionalized Halogenoximes by Chalyk, Bohdan A, Hrebeniuk, Kateryna V, Fil, Yulia V, Gavrilenko, Konstantin S, Rozhenko, Alexander B, Vashchenko, Bohdan V, Borysov, Oleksandr V, Biitseva, Angelina V, Lebed, Pavlo S, Bakanovych, Iulia, Moroz, Yurii S, Grygorenko, Oleksandr O

“…A comprehensive study on the synthesis of 5-fluoroalkyl-substituted isoxazoles starting from functionalized halogenoximes is reported. One-pot metal-free [3 +…”
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Regioselective Synthesis of Functionalized 3- or 5‑Fluoroalkyl Isoxazoles and Pyrazoles from Fluoroalkyl Ynones and Binucleophiles by Chalyk, Bohdan A, Khutorianskyi, Andrii, Lysenko, Andrii, Fil, Yulia, Kuchkovska, Yuliya O, Gavrilenko, Konstantin S, Bakanovych, Iulia, Moroz, Yurii S, Gorlova, Alina O, Grygorenko, Oleksandr O

“…A facile synthetic route toward either 3- or 5-fluoroalkyl-substituted isoxazoles or pyrazoles containing an additional functionalization site was developed…”
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Bicyclic Pyrrolidines for Medicinal Chemistry via [3 + 2]-Cycloaddition by Savych, Vladimir I, Mykhalchuk, Vladimir L, Melnychuk, Pavlo V, Isakov, Andrii O, Savchuk, Taras, Timoshenko, Vadim M, Siry, Sergiy A, Pavlenko, Sergiy O, Kovalenko, Dmytro V, Hryshchuk, Oleksandr V, Reznik, Vitalii A, Chalyk, Bohdan A, Yarmolchuk, Vladimir S, Rusanov, Eduard B, Mykhailiuk, Pavel K

“…A general approach to bicyclic fused pyrrolidines via [3 + 2]-cycloaddition between nonstabilized azomethyne ylide and endocyclic electron-deficient alkenes…”
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Synthesis of functionalized 4,5-dihydroisoxazoles decorated with the dimethylphosphinoyl group by Fedyk, Andrii V., Chalyk, Bohdan A.

“…Aim. To synthesize a hybrid molecular platform incorporating dimethylphosphinoyl and 4,5-dihydroisoxazole moieties suitable for the creation of focused…”
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Divergent Synthesis of Novel 3(5)‐Aminoazole–Benzopyrone Hybrids and their Evaluation as α‐Glucosidase Inhibitors by Myshko, Andrii S., Mrug, Galyna P., Bondarenko, Svitlana P., Demydchuk, Bohdan A., Kobzar, Oleksandr L., Buldenko, Vladyslav M., Vovk, Andriy I., Frasinyuk, Mykhaylo

“…An efficient approach has been developed for the trapping in situ generated benzopyrone‐based ortho‐quinone methide intermediates by 3‐ and 5‐amino pyrazoles…”
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Reductive Recyclization of sp 3 -Enriched Functionalized Isoxazolines into α-Hydroxy Lactams by Chalyk, Bohdan A, Khutorianskyi, Andrii V, Vashchenko, Bohdan V, Danyleiko, Kyrylo, Grynyova, Anastasiia, Osipova, Anastasiia O, Kozytskiy, Andriy, Syniuchenko, Darya, Tsymbaliuk, Anton, Gavrilenko, Konstantin S, Biitseva, Angelina V, Volochnyuk, Dmitriy M, Komarov, Igor V, Grygorenko, Oleksandr O

“…An efficient synthesis (up to a 200 g scale) of 3-hydroxypyrrolidin-2-ones bearing alkyl substituents or functional groups at the C-5 position is described…”
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Synthesis of 6‐Azaspiro[4.3]alkanes: Innovative Scaffolds for Drug Discovery by Chalyk, Bohdan A., Isakov, Andrei A., Butko, Maryna V., Hrebeniuk, Kateryna V., Savych, Olena V., Kucher, Olexandr V., Gavrilenko, Konstantin S., Druzhenko, Tetiana V., Yarmolchuk, Vladimir S., Zozulya, Sergey, Mykhailiuk, Pavel K.

“…New scaffolds for drug discovery, 6‐azaspiro[4.3]alkanes, have been synthesized in two steps from four‐membered‐ring ketones: cyclobutanone, thienone,…”
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Turbulent processes in the Earth's magnetotail: spectral and statistical research by Kozak, Liudmyla V., Petrenko, Bohdan A., Lui, Anthony T. Y., Kronberg, Elena A., Grigorenko, Elena E., Prokhorenkov, Andrew S.

“…We use the magnetic field measurements from four spacecraft of the Cluster-II mission (three events from 2005 to 2015) for the analysis of turbulent processes…”
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Carboxylated chalcones and related flavonoids as inhibitors of xanthine oxidase by Kobzar, Oleksandr L., Tatarchuk, Alona V., Mrug, Galyna P., Bondarenko, Svitlana P., Demydchuk, Bohdan A., Frasinyuk, Mykhaylo S., Vovk, Andriy I.

“…Carboxylated chalcones and other related flavonoids were synthesized and evaluated as inhibitors of xanthine oxidase, which is a known target for synthetic and…”
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Synthesis of Bi‐ and Polyfunctional Isoxazoles from Amino Acid Derived Halogenoximes and Active Methylene Nitriles by Chalyk, Bohdan A., Hrebeniuk, Kateryna V., Gavrilenko, Konstantin S., Shablykin, Oleh V., Yanshyna, Oksana O., Bash, Daniil, Mykhailiuk, Pavel K., Liashuk, Oleksandr S., Grygorenko, Oleksandr O.

“…The reaction of chloroximes that have a protected amino group and active methylene nitriles under basic conditions has been shown to give functionalized…”
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Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery by Chalyk, Bohdan A., Butko, Maryna V., Yanshyna, Oksana O., Gavrilenko, Konstantin S., Druzhenko, Tetiana V., Mykhailiuk, Pavel K.

“…Invited for the cover of this issue is the group of Pavel K. Mykhailiuk at the Taras Shevchenko National University of Kyiv and Enamine Ltd. The image depicts…”
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Synthesis of 4‐Hetarylisoxazoles from Amino Acid‐Derived Halogenoximes and Push‐Pull Enamines by Chalyk, Bohdan A., Hrebeniuk, Kateryna V., Gavrilenko, Konstantin S., Kulik, Irene B., Rozhenko, Alexander B., Volochnyuk, Dmitriy M., Liashuk, Oleksandr S., Grygorenko, Oleksandr O.

“…An approach to 4‐hetarylisoxazole‐derived amines and other related 3,4‐disubstituted isoxazoles which relies on [3+2] cycloaddition of amino acid‐derived…”
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Front Cover: Synthesis of Spirocyclic Pyrrolidines: Advanced Building Blocks for Drug Discovery (Chem. Eur. J. 66/2017) by Chalyk, Bohdan A., Butko, Maryna V., Yanshyna, Oksana O., Gavrilenko, Konstantin S., Druzhenko, Tetiana V., Mykhailiuk, Pavel K.

“…The cover picture shows novel building blocks for drug discovery—spirocyclic pyrrolidine. The synthesis starts from common four‐, five‐, six‐ and…”
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Polymorphic transition due to grinding: the case of 3‐[1‐(tert‐butoxycarbonyl)azetidin‐3‐yl]‐1,2‐oxazole‐4‐carboxylic acid by Konovalova, Irina S., Shaposhnyk, Anna M., Baumer, Vyacheslav N., Chalyk, Bohdan A., Shishkina, Svitlana V.

“…A polymorphic transition as a result of grinding was found for 3‐[1‐(tert‐butoxycarbonyl)azetidin‐3‐yl]‐1,2‐oxazole‐4‐carboxylic acid. The thorough study of…”
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A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho‐Hydroxylated Deoxybenzoins by Mrug, Galyna P., Demydchuk, Bohdan A., Bondarenko, Svitlana P., Sviripa, Vitaliy M., Wyrebek, Przemyslaw, Mohler, James L., Fiandalo, Michael V., Liu, Chunming, Frasinyuk, Mykhaylo S., Watt, David S.

“…As part of a program focused on the development of new antineoplastic agents based on scaffolds found in natural products, we explored the isoflavone family as…”
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