Search Results - "Bohach, Gregory A"

A novel core genome-encoded superantigen contributes to lethality of community-associated MRSA necrotizing pneumonia by Wilson, Gillian J, Seo, Keun Seok, Cartwright, Robyn A, Connelley, Timothy, Chuang-Smith, Olivia N, Merriman, Joseph A, Guinane, Caitriona M, Park, Joo Youn, Bohach, Gregory A, Schlievert, Patrick M, Morrison, W Ivan, Fitzgerald, J Ross

“…Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune modulation and severe systemic illnesses such as Staphylococcus aureus…”
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Beta toxin catalyzes formation of nucleoprotein matrix in staphylococcal biofilms by Huseby, Medora J., Kruse, Andrew C., Digre, Jeff, Kohler, Petra L., Vocke, Jillian A., Mann, Ethan E., Bayles, Kenneth W., Bohach, Gregory A., Schlievert, Patrick M., Ohlendorf, Douglas H., Earhart, Cathleen A., Novick, Richard P.

“…Biofilms are surface-associated communities of microbes encompassed by an extracellular matrix. It is estimated that 80% of all bacterial infections involve…”
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Outer Membrane Protein X (Ail) Contributes to Yersinia pestis Virulence in Pneumonic Plague and Its Activity Is Dependent on the Lipopolysaccharide Core Length by Kolodziejek, Anna M, Schnider, Darren R, Rohde, Harold N, Wojtowicz, Andrzej J, Bohach, Gregory A, Minnich, Scott A, Hovde, Carolyn J

“…Yersinia pestis, the causative agent of plague, is one of the most virulent microorganisms known. The outer membrane protein X (OmpX) in Y. pestis KIM is…”
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Standard Nomenclature for the Superantigens Expressed by Staphylococcus by Lina, Gerard, Bohach, Gregory A., Nair, Sean P., Hiramatsu, Keiichi, Jouvin-Marche, Evelyn, Mariuzza, Roy

“…The International Nomenclature Committee for Staphylococcal Superantigens proposes an international procedure for the designation of newly described…”
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Structure and Biological Activities of Beta Toxin from Staphylococcus aureus by HUSEBY, Medora, SHI, Ke, BROWN, C. Kent, DIGRE, Jeff, MENGISTU, Fikre, KEUN SEOK SEO, BOHACH, Gregory A, SCHLIEVERT, Patrick M, OHLENDORF, Douglas H, EARHART, Cathleen A

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Neutrophils are resistant to Yersinia YopJ/P-induced apoptosis and are protected from ROS-mediated cell death by the type III secretion system by Spinner, Justin L, Seo, Keun Seok, O'Loughlin, Jason L, Cundiff, Jennifer A, Minnich, Scott A, Bohach, Gregory A, Kobayashi, Scott D

“…The human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against…”
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An Enterotoxin-Bearing Pathogenicity Island in Staphylococcus epidermidis by MADHUSOODANAN, Jyoti, KEUN SEOK SEO, DAUGHERTY, Sean C, ANN LINDLEY GILL, BOHACH, Gregory A, GILL, Steven R, REMORTEL, Brian, JOO YOUN PARK, SUN YOUNG HWANG, FOX, Lawrence K, YONG HO PARK, DEOBALD, Claudia F, DAN WANG, SONG LIU

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Physiological Levels of Glucose Induce Membrane Vesicle Secretion and Affect the Lipid and Protein Composition of Yersinia pestis Cell Surfaces by KOLODZIEJEK, Anna M, CAPLAN, Allan B, BOHACH, Gregory A, PASZCZYNSKI, Andrzej J, MINNICH, Scott A, HOVDE, Carolyn J

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A quantitative real time PCR method to analyze T cell receptor Vβ subgroup expansion by staphylococcal superantigens by Seo, Keun Seok, Park, Joo Youn, Terman, David S, Bohach, Gregory A

“…Abstract Background Staphylococcal enterotoxins (SEs), SE-like (SEl) toxins, and toxic shock syndrome toxin-1 (TSST-1), produced by Staphylococcus aureus ,…”
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Characterization of a Staphylococcus aureus Surface Virulence Factor That Promotes Resistance to Oxidative Killing and Infectious Endocarditis by Malachowa, Natalia, Kohler, Petra L, Schlievert, Patrick M, Chuang, Olivia N, Dunny, Gary M, Kobayashi, Scott D, Miedzobrodzki, Jacek, Bohach, Gregory A, Seo, Keun Seok

“…Staphylococcus aureus is a prominent human pathogen and a leading cause of community- and hospital-acquired bacterial infections worldwide. Herein, we describe…”
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Long-Term Staphylococcal Enterotoxin C1 Exposure Induces Soluble Factor-Mediated Immunosuppression by Bovine CD4+ and CD8+ T Cells by Seo, Keun Seok, Lee, Sang Un, Park, Yong Ho, Davis, William C, Fox, Lawrence K, Bohach, Gregory A

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Role of a New Intimin/Invasin-Like Protein in Yersinia pestis Virulence by Seo, Keun Seok, Kim, Jong Wan, Park, Joo Youn, Viall, Austin K, Minnich, Scott S, Rohde, Harold N, Schnider, Darren R, Lim, Seung Yong, Hong, Joon Bae, Hinnebusch, B Joseph, O'Loughlin, Jason L, Deobald, Claudia F, Bohach, Gregory A, Hovde, Carolyn J, Minnich, Scott A

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Characterization of a Putative Pathogenicity Island from Bovine Staphylococcus aureus Encoding Multiple Superantigens by Fitzgerald, J R, Monday, S R, Foster, T J, Bohach, G A, Hartigan, P J, Meaney, W J, Smyth, C J

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Characterization of Staphylococcus aureus Enterotoxin L by ORWIN, Paul M, FITZGERALD, J. Ross, LEUNG, Donald Y. M, GUTIERREZ, Juan A, BOHACH, Greeory A, SCHLIEVERT, Patrick M

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Deletion of Yersinia pestis ail Causes Temperature-Sensitive Pleiotropic Effects, Including Cell Lysis, That Are Suppressed by Carbon Source, Cations, or Loss of Phospholipase A Activity by Kolodziejek, Anna M, Hovde, Carolyn J, Bohach, Gregory A, Minnich, Scott A

“…Maintenance of phospholipid (PL) and lipopoly- or lipooligosaccharide (LPS or LOS) asymmetry in the outer membrane (OM) of Gram-negative bacteria is essential…”
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Characterization of a Novel Staphylococcal Enterotoxin-like Superantigen, a Member of the Group V Subfamily of Pyrogenic Toxins by Orwin, Paul M, Leung, Donald Y. M, Tripp, Timothy J, Bohach, Gregory A, Earhart, Cathleen A, Ohlendorf, Douglas H, Schlievert, Patrick M

“…Staphylococcus aureus is an important human pathogen, causing a variety of diseases. Major virulence factors of this organism include staphylococcal…”
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Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague by Airhart, Christina L, Rohde, Harold N, Bohach, Gregory A, Hovde, Carolyn J, Deobald, Claudia F, Lee, Stephen S, Minnich, Scott A

“…1 Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, ID 83844-3052, USA 2 Department of Statistics, University of…”
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Staphylococcal Fibronectin Binding Protein Interacts with Heat Shock Protein 60 and Integrins: Role in Internalization by Epithelial Cells by DZIEWANOWSKA, Katarzyna, CARSON, Andrew R, PATTI, Joseph M, DEOBALD, Claudia F, BAYLES, Kenneth W, BOHACH, Gregory A

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Superantigen-mediated differentiation of bovine monocytes into dendritic cells by Seo, Keun Seok, Park, Joo Youn, Davis, William C., Fox, Lawrence K., McGuire, Mark A., Park, Yong Ho, Bohach, Gregory A.

“…Although many effects of staphylococcal superantigens (SAg) on T cells are well established, less is known about their effects on APC. In this study, bovine…”
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The Structure of the Superantigen Exfoliative Toxin A Suggests a Novel Regulation as a Serine Protease by Vath, Gregory M, Earhart, Cathleen A, Rago, James V, Kim, Michael H, Bohach, Gregory A, Schlievert, Patrick M, Ohlendorf, Douglas H

“…Exfoliative toxin A (ETA) causes staphylococcal scalded skin syndrome which is characterized by a specific intraepidermal separation of layers of the skin. The…”
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