Search Results - "Bogutz, Aaron B."

Maternal DNA Methylation Regulates Early Trophoblast Development by Branco, Miguel R., King, Michelle, Perez-Garcia, Vicente, Bogutz, Aaron B., Caley, Matthew, Fineberg, Elena, Lefebvre, Louis, Cook, Simon J., Dean, Wendy, Hemberger, Myriam, Reik, Wolf

“…Critical roles for DNA methylation in embryonic development are well established, but less is known about its roles during trophoblast development, the…”
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DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells by Ito, Takamasa, Kubiura-Ichimaru, Musashi, Murakami, Yuri, Bogutz, Aaron B, Lefebvre, Louis, Suetake, Isao, Tajima, Shoji, Tada, Masako

“…DNA methylation (DNAme; 5-methylcytosine, 5mC) plays an essential role in mammalian development, and the 5mC profile is regulated by a balance of opposing…”
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Evolution of imprinting via lineage-specific insertion of retroviral promoters by Bogutz, Aaron B., Brind’Amour, Julie, Kobayashi, Hisato, Jensen, Kristoffer N., Nakabayashi, Kazuhiko, Imai, Hiroo, Lorincz, Matthew C., Lefebvre, Louis

“…Imprinted genes are expressed from a single parental allele, with the other allele often silenced by DNA methylation (DNAme) established in the germline. While…”
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Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing by Mochizuki, Kentaro, Sharif, Jafar, Shirane, Kenjiro, Uranishi, Kousuke, Bogutz, Aaron B., Janssen, Sanne M., Suzuki, Ayumu, Okuda, Akihiko, Koseki, Haruhiko, Lorincz, Matthew C.

“…Silencing of a subset of germline genes is dependent upon DNA methylation (DNAme) post-implantation. However, these genes are generally hypomethylated in the…”
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Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage by Bogutz, Aaron B, Oh-McGinnis, Rosemary, Jacob, Karen J, Ho-Lau, Rita, Gu, Ting, Gertsenstein, Marina, Nagy, Andras, Lefebvre, Louis

“…The basic helix-loop-helix (bHLH) transcription factor ASCL2 plays essential roles in diploid multipotent trophoblast progenitors, intestinal stem cells,…”
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Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction by Oh-McGinnis, Rosemary, Bogutz, Aaron B., Lefebvre, Louis

“…Several imprinted genes have been implicated in the regulation of placental function and embryonic growth. On distal mouse chromosome 7, two clusters of…”
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Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST by Kelsey, Angela D, Yang, Christine, Leung, Danny, Minks, Jakub, Dixon-McDougall, Thomas, Baldry, Sarah E L, Bogutz, Aaron B, Lefebvre, Louis, Brown, Carolyn J

“…X-chromosome inactivation is a striking example of epigenetic silencing in which expression of the long non-coding RNA XIST initiates the…”
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Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA) by Richard Albert, Julien, Koike, Tasuku, Younesy, Hamid, Thompson, Richard, Bogutz, Aaron B, Karimi, Mohammad M, Lorincz, Matthew C

“…Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions…”
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Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2 by MacIsaac, Julia L, Bogutz, Aaron B, Morrissy, A Sorana, Lefebvre, Louis

“…The gene Mest (also known as Peg1) is regulated by genomic imprinting in the mouse and only the paternal allele is active for transcription. MEST is similarly…”
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An Extended Domain of Kcnq1ot1 Silencing Revealed by an Imprinted Fluorescent Reporter by Jones, Meaghan J., Bogutz, Aaron B., Lefebvre, Louis

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome by Oh-McGinnis, Rosemary, Bogutz, Aaron B, Lee, Kang Yun, Higgins, Michael J, Lefebvre, Louis

“…Several imprinted genes have been implicated in the process of placentation. The distal region of mouse chromosome 7 (Chr 7) contains at least ten imprinted…”
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DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells by Takamasa Ito, Musashi Kubiura-Ichimaru, Yuri Murakami, Aaron B. Bogutz, Louis Lefebvre, Isao Suetake, Shoji Tajima, Masako Tada

“…DNA methylation (DNAme; 5-methylcytosine, 5mC) plays an essential role in mammalian development, and the 5mC profile is regulated by a balance of opposing…”
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