Search Results - "Bogoyevitch, Marie A."

JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships by Zeke, András, Misheva, Mariya, Reményi, Attila, Bogoyevitch, Marie A

“…The c-Jun N-terminal kinases (JNKs), as members of the mitogen-activated protein kinase (MAPK) family, mediate eukaryotic cell responses to a wide range of…”
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Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases by BOGOYEVITCH, Marie A, KOBE, Bostjan

“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting by Bogoyevitch, Marie A.

“…The c‐Jun N‐terminal kinases (JNKs) are members of the mitogen‐activated protein kinase (MAPK) family. In mammalian genomes, three genes encode the JNK family…”
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Respiratory Syncytial Virus Matrix Protein Is Sufficient and Necessary to Remodel Host Mitochondria in Infection by Hu, MengJie, Bogoyevitch, Marie A, Jans, David A

“…Although respiratory syncytial virus (RSV) is the most common cause of respiratory infection in infants, immunosuppressed adults and the elderly worldwide,…”
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The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways by Zhang, Sunyuan, Williamson, Nicholas A., Duvick, Lisa, Lee, Alexander, Orr, Harry T., Korlin-Downs, Austin, Yang, Praseuth, Mok, Yee-Foong, Jans, David A., Bogoyevitch, Marie A.

“…The expanded polyglutamine (polyQ) tract form of ataxin-1 drives disease progression in spinocerebellar ataxia type 1 (SCA1). Although known to form…”
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Subversion of Host Cell Mitochondria by RSV to Favor Virus Production is Dependent on Inhibition of Mitochondrial Complex I and ROS Generation by Hu, MengJie, Bogoyevitch, Marie A, Jans, David A

“…Respiratory syncytial virus (RSV) is a key cause of severe respiratory infection in infants, immunosuppressed adults, and the elderly worldwide, but there is…”
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Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus by Moslehi, Maryam, Ng, Dominic C. H., Bogoyevitch, Marie A.

“…Doublecortin X (DCX), known to be essential for neuronal migration and cortical layering in the developing brain, is a 40 kDa microtubule (MT)-associated…”
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Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness by Hinde, Elizabeth, Pandžić, Elvis, Yang, Zhengmin, Ng, Ivan H. W., Jans, David A., Bogoyevitch, Marie A., Gratton, Enrico, Gaus, Katharina

“…Oligomerization of transcription factors controls their translocation into the nucleus and DNA-binding activity. Here we present a fluorescence microscopy…”
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Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production by Hu, MengJie, Schulze, Keith E, Ghildyal, Reena, Henstridge, Darren C, Kolanowski, Jacek L, New, Elizabeth J, Hong, Yuning, Hsu, Alan C, Hansbro, Philip M, Wark, Peter Ab, Bogoyevitch, Marie A, Jans, David A

“…Although respiratory syncytial virus (RSV) is responsible for more human deaths each year than influenza, its pathogenic mechanisms are poorly understood. Here…”
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p32 protein levels are integral to mitochondrial and endoplasmic reticulum morphology, cell metabolism and survival by Hu, Mengjie, Crawford, Simon A, Henstridge, Darren C, Ng, Ivan H W, Boey, Esther J H, Xu, Yuekang, Febbraio, Mark A, Jans, David A, Bogoyevitch, Marie A

“…p32 [also known as HABP1 (hyaluronan-binding protein 1), gC1qR (receptor for globular head domains complement 1q) or C1qbp (complement 1q-binding protein)] has…”
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WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression by Bogoyevitch, Marie A, Yeap, Yvonne Y C, Qu, Zhengdong, Ngoei, Kevin R, Yip, Yan Y, Zhao, Teresa T, Heng, Julian I, Ng, Dominic C H

“…The impact of aberrant centrosomes and/or spindles on asymmetric cell division in embryonic development indicates the tight regulation of bipolar spindle…”
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Oxidative stress impairs multiple regulatory events to drive persistent cytokine-stimulated STAT3 phosphorylation by Ng, Ivan H.W., Yeap, Yvonne Y.C., Ong, Lynette S.R., Jans, David A., Bogoyevitch, Marie A.

“…Although cytokine-driven STAT3 phosphorylation and activation are often transient, persistent activation of STAT3 is a hallmark of a range of pathologies and…”
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Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes by Ng, Ivan H W, Ng, Dominic C H, Jans, David A, Bogoyevitch, Marie A

“…Phosphorylation of STAT3 (signal transducer and activator of transcription 3) is critical for its nuclear import and transcriptional activity. Although a…”
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Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation by Lim, Nicholas R, Yeap, Yvonne Y C, Ang, Ching-Seng, Williamson, Nicholas A, Bogoyevitch, Marie A, Quinn, Leonie M, Ng, Dominic C H

“…Mitotic spindle organization is regulated by centrosomal kinases that potentiate recruitment of spindle-associated proteins required for normal mitotic…”
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Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential by Bogoyevitch, Marie A., Boehm, Ingrid, Oakley, Aaron, Ketterman, Albert J., Barr, Renae K.

“…The c-Jun N-terminal protein kinases (JNKs) form one subfamily of the mitogen-activated protein kinase (MAPK) group of serine/threonine protein kinases. The…”
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C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress by Meyerowitz, Jodi, Parker, Sarah J, Vella, Laura J, Ng, Dominic Ch, Price, Katherine A, Liddell, Jeffrey R, Caragounis, Aphrodite, Li, Qiao-Xin, Masters, Colin L, Nonaka, Takashi, Hasegawa, Masato, Bogoyevitch, Marie A, Kanninen, Katja M, Crouch, Peter J, White, Anthony R

“…TDP-43 proteinopathies are characterized by loss of nuclear TDP-43 expression and formation of C-terminal TDP-43 fragmentation and accumulation in the…”
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The JNK1/JNK3 interactome--contributions by the JNK3 unique N-terminus and JNK common docking site residues by Chen, Wei-Kai, Yeap, Yvonne Y C, Bogoyevitch, Marie A

“…The c-Jun N-terminal Kinases (JNKs) play important roles in cell responses to stress or growth factor stimulation. The JNK1α1 isoform shares >90% identity with…”
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TrawlerWeb: an online de novo motif discovery tool for next-generation sequencing datasets by Dang, Louis T, Tondl, Markus, Chiu, Man Ho H, Revote, Jerico, Paten, Benedict, Tano, Vincent, Tokolyi, Alex, Besse, Florence, Quaife-Ryan, Greg, Cumming, Helen, Drvodelic, Mark J, Eichenlaub, Michael P, Hallab, Jeannette C, Stolper, Julian S, Rossello, Fernando J, Bogoyevitch, Marie A, Jans, David A, Nim, Hieu T, Porrello, Enzo R, Hudson, James E, Ramialison, Mirana

“…A strong focus of the post-genomic era is mining of the non-coding regulatory genome in order to unravel the function of regulatory elements that coordinate…”
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Identification of the Critical Features of a Small Peptide Inhibitor of JNK Activity by Barr, Renae K., Kendrick, Tulene S., Bogoyevitch, Marie A.

“…The c-Jun N-terminal kinases (JNKs) are a subfamily of the mitogen-activated protein kinases (MAPKs). Although progress in evaluating the functions of other…”
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The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer by Yang, Sundy N.Y., Atkinson, Sarah C., Wang, Chunxiao, Lee, Alexander, Bogoyevitch, Marie A., Borg, Natalie A., Jans, David A.

“…Infection by RNA viruses such as human immunodeficiency virus (HIV)-1, influenza, and dengue virus (DENV) represent a major burden for human health worldwide…”
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