Search Results - "Boggs, Sharon"

Imidazopyridine-5,6,7,8-tetrahydro-8-quinolinamine derivatives with potent activity against HIV-1 by Gudmundsson, Kristjan S., Boggs, Sharon D., Catalano, John G., Svolto, Angilique, Spaltenstein, Andrew, Thomson, Michael, Wheelan, Pat, Jenkinson, Stephen

“…Synthesis of several novel imidazopyridine-5,6,7,8-tetrahydro-8-quinolinamine derivatives with potent activity against HIV-1 are described. Synthesis of…”
Get full text

Kilogram-Scale Synthesis of the CXCR4 Antagonist GSK812397 by Boggs, Sharon, Elitzin, Vassil I, Gudmundsson, Kristjan, Martin, Michael T, Sharp, Matthew J

“…An improved, scalable synthesis of the CXCR4 antagonist GSK812397 is described. This new route was recently scaled up in 50 L fixed equipment to afford 1.2 kg…”
Get full text

Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists by Smalley, Jr, Terrence L, Boggs, Sharon, Caravella, Justin A, Chen, Lihong, Creech, Katrina L, Deaton, David N, Kaldor, Istvan, Parks, Derek J

“…The farnesoid X receptor (FXR) may play a crucial role in a number of metabolic diseases and, as such, could potentially serve as a target for the development…”
Get full text

Substituted tetrahydrocarbazoles with potent activity against human papillomaviruses by Gudmundsson, Kristjan S., Sebahar, Paul R., Richardson, Leah D’Aurora, Catalano, John G., Boggs, Sharon D., Spaltenstein, Andrew, Sethna, Phiroze B., Brown, Kevin W., Harvey, Robert, Romines, Karen R.

“…Synthesis of a series of substituted 1-aminotetrahydrocarbazoles with potent activity against human papillomaviruses is described. Synthetic approaches…”
Get full text

Synthesis of a novel tricyclic 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system and CXCR4 antagonists with potent activity against HIV-1 by Catalano, John G., Gudmundsson, Kristjan S., Svolto, Angilique, Boggs, Sharon D., Miller, John F., Spaltenstein, Andrew, Thomson, Michael, Wheelan, Pat, Minick, Doug J., Phelps, Dean P., Jenkinson, Stephen

“…Stereorandom and diastereoselective syntheses of a novel 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system are described. Derivatives of all four…”
Get full text

Tetrahydrocarbazole amides with potent activity against human papillomaviruses by Gudmundsson, Kristjan S., Boggs, Sharon D., Sebahar, Paul R., Richardson, Leah D’Aurora, Spaltenstein, Andrew, Golden, Pamela, Sethna, Phiroze B., Brown, Kevin W., Moniri, Kelly, Harvey, Robert, Romines, Karen R.

“…Synthesis and optimization of a series of tetrahydrocarbazole amides with potent activity against human papillomaviruses and desirable development properties…”
Get full text

Efficient Asymmetric Synthesis of N-[(1R)-6-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-2-pyridinecarboxamide for Treatment of Human Papillomavirus Infections by Boggs, Sharon D, Cobb, Jeremy D, Gudmundsson, Kristjan S, Jones, Lynda A, Matsuoka, Richard T, Millar, Alan, Patterson, Daniel E, Samano, Vicente, Trone, Mark D, Xie, Shiping, Zhou, Xiao-ming

“…An efficient asymmetric synthesis of N-[(1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-2-pyridinecarboxamide 1, a potential treatment for human…”
Get full text

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch by Williams, Shawn, Bledsoe, Randy K, Collins, Jon L, Boggs, Sharon, Lambert, Millard H, Miller, Ann B, Moore, John, McKee, David D, Moore, Linda, Nichols, Jason, Parks, Derek, Watson, Mike, Wisely, Bruce, Willson, Timothy M

“…The x-ray crystal structures of the human liver X receptor beta ligand binding domain complexed to sterol and nonsterol agonists revealed a perpendicular…”
Get full text

Education of Rural Community Pharmacists To Provide Nutrition Information by Boggs, Sharon A. C

“…A survey of 130 rural community pharmacists in Washington State found 70% in towns with five or fewer pharmacies; almost all provided nutrition information to…”
Get more information

N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1 by Haffner, Curt D., Thomson, Stephen A., Guo, Yu, Schaller, Lee T., Boggs, Sharon, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, J. Patrick

“…We report the synthesis and in vitro activity of a series of novel N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs. These…”
Get full text

N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benz amide analogs as potent Kv1.3 inhibitors. Part 1 by Haffner, Curt D, Thomson, Stephen A, Guo, Yu, Schaller, Lee T, Boggs, Sharon, Dickerson, Scott, Gobel, Jeff, Gillie, Dan, Condreay, JPatrick

“…We report the synthesis and in vitro activity of a series of novel N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}b enzamide analogs. These…”
Get full text

X-ray Crystal Structure of the Liver X Receptor β Ligand Binding Domain by Shawn Williams, Randy K. Bledsoe, Jon L. Collins, Sharon Boggs, Millard H. Lambert, Ann B. Miller, John Moore, David D. McKee, Linda Moore, Jason Nichols, Derek Parks, Mike Watson, Bruce Wisely, Timothy M. Willson

“…The x-ray crystal structures of the human liver X receptor β ligand binding domain complexed to sterol and nonsterol agonists revealed a perpendicular…”
Get full text

X-ray Crystal Structure of the Liver X Receptor β Ligand Binding Domain by Williams, Shawn, Bledsoe, Randy K., Collins, Jon L., Boggs, Sharon, Lambert, Millard H., Miller, Ann B., Moore, John, McKee, David D., Moore, Linda, Nichols, Jason, Parks, Derek, Watson, Mike, Wisely, Bruce, Willson, Timothy M.

“…The x-ray crystal structures of the human liver X receptor β ligand binding domain complexed to sterol and nonsterol agonists revealed a perpendicular…”
Get full text

The Molecular Pharmacology of Lysophosphatidate Signaling by SANTOS, WEBSTER L., ROSSI, JASON A., BOGGS, SHARON D., MACDONALD, TIMOTHY L.

Get full text