Search Results - "Boggs, Sallie S"

Expression of murine CD34 by fetal liver NK cell progenitors by Lu, Jing, Patrene, Kenneth D, Herberman, Ronald B, Boggs, Sallie S

“…Although 14.5-day murine fetal liver (FL) has few, if any, mature natural killer (NK) cells, culture of FL with recombinant human IL-2 (rhIL-2) and stroma from…”
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Insertion of DNA sequences into the human chromosomal β -globin locus by homologous recombination by Smithies, Oliver, Gregg, Ronald G, Boggs, Sallie S, Koralewski, Michael A, Kucherlapati, Raju S

“…A 'rescuable' plasmid containing globin gene sequences allowing recombination with homologous chromosomal sequences has enabled us to produce, score and clone…”
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The effect of DFMO induced uptake of [3H] putrescine on human glioma cells by REDGATE, Edward S, ALEXANDER, Dominic, MAGRA, T. Ryan, HENRETTY, Joseph S, PATRENE, Kenneth D, BOGGS, Sallie S

“…Polyamine synthesis inhibitors, such as a-difluoromethylornithine (DFMO), inhibit tumor cell growth in vitro and in vivo. However, upon cessation of treatment,…”
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Effects of Recombinant Cytokines on Colony Formation by Irradiated Human Cord Blood CD34+ Hematopoietic Progenitor Cells by Goff, Julie P., Shields, Donna S., Boggs, Sallie S., Greenberger, Joel S.

“…The role of recombinant hematopoietic growth factors in radiation repair has become a subject of increasing interest in both clinical and basic radiobiology…”
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Characterization of the stage in natural killer cell development in 14.5-day mouse fetal liver using adult bone marrow stroma by Lu, Jing, Patrene, Kenneth D, Appasamy, Pierette M, Herberman, Ronald B, Boggs, Sallie S

“…Nonstimulated fetal liver (FL) from 14.5-day gestation mice had no natural killer (NK) cell activity and <3% expressed NK1.1. Even after short-term (3–4 day)…”
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NKR-P1+ cells localize selectively in rat 9L gliosarcomas but have reduced cytolytic function by CHAMBERS, W. H, BOZIK, M. E, BRISSETTE-STORKUS, C. S, BASSE, P, REDGATE, E, WATKINS, S, BOGGS, S. S

“…To better understand immune responses to brain tumors and to develop possible approaches for immunotherapy, we have investigated the leukocyte populations…”
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Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach by Colson, YL, Li, H, Boggs, SS, Patrene, KD, Johnson, PC, Ildstad, ST

“…For over 40 years, the association between hemopoietic chimerism and donor-specific tolerance for allografts has been recognized. However, toxicity associated…”
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Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice by Li, H, Kaufman, CL, Boggs, SS, Johnson, PC, Patrene, KD, Ildstad, ST

“…Evidence in experimental models suggests that many autoimmune diseases can be prevented by transplantation of bone marrow from disease-resistant donors. For…”
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Cellular replication kinetics and persistence of sister chromatid exchange-inducing lesions in normal and lymphoma AKR cells following exposure to 1,3-bis(2-chloroethyl)-1-nitrosourea by Biegel, J A, Conner, M K, Boggs, S S

“…The present studies were designed to evaluate the role of cell cycle time and time of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) administration on the…”
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In vivo sister chromatid exchange and cellular replication kinetics of normal and lymphoma AKR bone marrow cells by Biegel, J A, Boggs, S S, Conner, M K

“…The recent development of an AKR(Rb6.15)1Ald lymphoma model in our laboratory presents a unique means of comparing sister chromatid exchange (SCE) frequencies…”
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Minimal bone marrow damage in mice given bleomycin by Boggs, S S, Sartiano, G P, DeMezza, A

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A nonlethal conditioning approach to achieve durable multilineage mixed chimerism and tolerance across major, minor, and hematopoietic histocompatibility barriers by Colson, YL, Wren, SM, Schuchert, MJ, Patrene, KD, Johnson, PC, Boggs, SS, Ildstad, ST

“…Reconstitution of lethally irradiated mice with a mixture of syngeneic and allogeneic (A+B-->A) bone marrow results in multilineage mixed allogeneic chimerism,…”
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Effects of bleomycin on PHA-stimulated lymphocytes and isolated hepatic nuclei by Sartiano, G P, Winkelstein, A, Lynch, W, Boggs, S S

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Cross-species bone marrow transplantation : evidence for tolerance induction, stem cell engraftment, and maturation of T lymphocytes in a xenogeneic stromal environment (rat → mouse) by ILDSTAD, S. T, WREN, S. M, BOGGS, S. S, HRONAKES, M. L, VECCHINI, F, VAN DEN BRINK, M. R. M

“…Transplantation of untreated F344 rat bone marrow into irradiated B10 mouse recipients (non-TCD F344---B10) to produce fully xenogeneic chimeras resulted in…”
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Retroviral vectors for use in human gene therapy for cancer, Gaucher disease, and arthritis by Robbins, P D, Tahara, H, Mueller, G, Hung, G, Bahnson, A, Zitvogel, L, Galea-Lauri, J, Ohashi, T, Patrene, K, Boggs, S S

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Lack of natural killer cell precursors in fetal liver of Ikaros knockout mutant mice by Boggs, S S, Trevisan, M, Patrene, K, Geogopoulos, K

“…The role of Ikaros in early stages of natural killer (NK) cell differentiation was investigated using an in vitro system that promotes proliferation and…”
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The generation of natural killer (NK) cells from NK precursor cells in rat long-term bone marrow cultures by van den Brink, M R, Boggs, S S, Herberman, R B, Hiserodt, J C

“…In this report, we describe a novel long-term bone marrow culture (LTBMC) system to study the origin and generation of natural killer (NK) cells from NK…”
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Transduction of mobilized peripheral blood CD34+ cells with the glucocerebrosidase cDNA by Nimgaonkar, M T, Bahnson, A B, Boggs, S S, Ball, E D, Barranger, J A

“…Gaucher disease (GD), the most common human lysosomal storage disorder, results from a genetic deficiency of the enzyme glucocerebrosidase (GC). The cloning of…”
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Transduction of CD34+ enriched cord blood and Gaucher bone marrow cells by a retroviral vector carrying the glucocerebrosidase gene by Bahnson, A B, Nimgaonkar, M, Fei, Y, Boggs, S S, Robbins, P D, Ohashi, T, Dunigan, J, Li, J, Ball, E D, Barranger, J A

“…One promising strategy for gene therapy of Gaucher disease involves ex vivo retroviral transduction of autologous hematopoietic stem cells. Studies in small…”
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Role of CD44 in the development of natural killer cells from precursors in long-term cultures of mouse bone marrow by Delfino, DV, Patrene, KD, DeLeo, AB, DeLeo, R, Herberman, RB, Boggs, SS

“…The role of the adhesion molecule CD44 in the development of NK cells was analyzed in a mouse long-term bone marrow culture system. After 4 wk of culture (day…”
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