Search Results - "Boggild, M D"

Susceptibility and outcome in MS: Associations with polymorphisms in pigmentation-related genes by PARTRIDGE, J. M, WEATHERBY, S. J. M, WOOLMORE, J. A, HIGHLAND, D. J, FRYER, A. A, MANN, C. L. A, BOGGILD, M. D, OLLIER, W. E. R, STRANGE, R. C, HAWKINS, C. P

“…Multiple sclerosis (MS) risk is determined by environment and genes. The authors investigated in 419 cases and 422 controls if polymorphism in the vitamin D…”
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Glutathione S-transferase polymorphisms in MS: Their relationship to disability by MANN, C. L. A, DAVIES, M. B, BOGGILD, M. D, ALLDERSEA, J, FRYER, A. A, JONES, P. W, KO, C. K, YOUNG, C, STRANGE, R. C, HAWKINS, C. P

“…Oxidative stress has been implicated in inflammatory demyelination. The glutathione S-transferase (GST) supergene family encodes isoenzymes that appear to be…”
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Molecular genetic studies of sporadic pituitary tumors by Boggild, M D, Jenkinson, S, Pistorello, M, Boscaro, M, Scanarini, M, McTernan, P, Perrett, C W, Thakker, R V, Clayton, R N

“…Tumor formation may result from the activation of dominant oncogenes or by inactivation of recessive, tumor suppressor genes. The role of such mutations in the…”
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The role of the PTPRC (CD45) mutation in the development of multiple sclerosis in the North West region of the United Kingdom by Nicholas, R S, Partridge, J, Donn, R P, Hawkins, C, Boggild, M D

“…Background: A point mutation in protein tyrosine phosphatase receptor, type c polypeptide (PTPRC) has been associated with familial multiple sclerosis. This CG…”
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HLA-DRB1 and disease outcome in multiple sclerosis by WEATHERBY, S. J. M, THOMSON, W, JONES, P. W, STRANGE, R. C, OLLIER, W. E. R, HAWKINS, C. P, PEPPER, L, DONN, R, WORTHINGTON, J, MANN, C. L. A, DAVIES, M. B, FRYER, A. A, BOGGILD, M. D, YOUNG, C. A

“…The association between susceptibility to multiple sclerosis (MS) and the class II MHC allele HLA-DRB1*15 is well established although a possible relationship…”
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Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity by Mann, C.L.A, Davies, M.B, Stevenson, V.L, Leary, S.M, Boggild, M.D, Ko Ko, C, Jones, P.W, Fryer, A.A, Strange, R.C, Thompson, A.J, Hawkins, C.P

“…We studied the association between clinical outcome in MS and allelic variants single nucleotide polymorphisms (SNPs) of interleukin-1α (IL-1α), IL-1β and a…”
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Polymorphisms of apolipoprotein E; outcome and susceptibility in multiple sclerosis by Weatherby, S.J.M., Mann, C.L.A., Davies, M.B., Carthy, D., Fryer, A.A., Boggild, M.D., Young, C., Strange, R.C., Ollier, W., Hawkins, C.P.

“…Allelic variants of the apolipoprotein E (APOE) gene influence the course of several neurological diseases. In multiple sclerosis the concentration of APOE in…”
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Cortical plaques visualised by fluid-attenuated inversion recovery imaging in relapsing multiple sclerosis by BOGGILD, M. D, WILLIAMS, R, HAQ, N, HAWKINS, C. P

“…Fluid-attenuated inversion recovery (FLAIR) imaging with prolonged inversion times allows generation of highly T2-weighted images of the brain with suppression…”
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Pan-Hypopituitarism and Diabetes Insipidus after a Heart Transplant by Vaidya, B, Cavet, J, Boggild, M D, Parry, G, Kendall-Taylor, P, Ball, S G

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Cerebral venous sinus thrombosis and antiphospholipid antibodies by Boggild, M. D., Sedhev, R. V., Fraser, D., Heron, J. R.

“…We report two cases of cerebral venous sinus thrombosis associated with an antibody to phospholipids, namely the lupus anticoagulant. Both patients later…”
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The glutathione S-transferases: polymerase chain reaction studies on the frequency of the GSTM1 0 genotype in patients with pituitary adenomas by Fryer, A A, Zhao, L, Alldersea, J, Boggild, M D, Perrett, C W, Clayton, R N, Jones, P W, Strange, R C

“…The frequency of the GSTM1 0 polymorphism at the glutathione S-transferase M1 locus has been determined in controls and patients with pituitary adenomas by…”
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Clinical and genetic changes in a case of a Cushing's carcinoma by Bates, A S, Buckley, N, Boggild, M D, Bicknell, E J, Perrett, C W, Broome, J C, Clayton, R N

“…A 30-year-old presented in 1984 with a clinically nonfunctional tumour which subsequently developed into a metastatic corticotrophinoma from which he died…”
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Polymorphisms of apolipoprotein E; outcome and susceptibility in multiple sclerosis by Weatherby, S JM, Mann, C LA, Davies, M B, Carthy, D, Fryer, A A, Boggild, M D, Young, C, Strange, R C, Ollier, W, Hawkins, C P

“…Allelic variants of the apolipoprotein E (APOE) gene influence the course of several neurological diseases. In multiple sclerosis the concentration of APOE in…”
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Acetonitrile ingestion: delayed onset of cyanide poisoning due to concurrent ingestion of acetone by Boggild, M. D., Peck, R. W., Tomson, C. R.

“…A fatal case of acetonitrile ingestion is reported. The patient presented having apparently taken an overdose but was well until around 24 hours after the…”
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Effectiveness and cost-effectiveness of interferon beta and glatiramer acetate in the UK Multiple Sclerosis Risk Sharing Scheme at 6 years: a clinical cohort study with natural history comparator by Palace, Jacqueline, Dr, Duddy, Martin, MD, Bregenzer, Thomas, PhD, Lawton, Michael, MPhil, Zhu, Feng, MSc, Boggild, Mike, MD, Piske, Benjamin, MSc, Robertson, Neil P, Prof, Oger, Joel, DM, Tremlett, Helen, PhD, Tilling, Kate, Prof, Ben-Shlomo, Yoav, Prof, Dobson, Charles, PhD

“…Summary Background In 2002, the UK's National Institute for Clinical Excellence (NICE) concluded that interferon beta and glatiramer acetate would be cost…”
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Audit of B-interferon treatment: expreience the first 100 patients within the Walton centre MS service by Di, Rag, CA, Young, MD, Boggild

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The District General Hospital as a Resource for the Provision of Neurological Services by Boggild, M D, Bowden, A N, Chadwick, D W, Doran, M, Enevoldson, T, Fletcher, N A, Hart, I, Humphrey, P, Lecky, B R F, Moore, A P, Smith, D, Steiger, M, Williams, I R, Young, C A

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Effect of vitamin D status on clinical pregnancy rates following in vitro fertilization by Garbedian, Kimberley, MD, Boggild, Miranda, MD, Moody, Joel, MD, Liu, Kimberly E., MD

“…Abstract Background: Recentstudies suggest that vitamin D may play a role in human reproduction. Our goal was to investigate whether vitamin D levels are…”
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