Search Results - "Bogers, M."

Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore by Urbani, Andrea, Giorgio, Valentina, Carrer, Andrea, Franchin, Cinzia, Arrigoni, Giorgio, Jiko, Chimari, Abe, Kazuhiro, Maeda, Shintaro, Shinzawa-Itoh, Kyoko, Bogers, Janna F. M., McMillan, Duncan G. G., Gerle, Christoph, Szabò, Ildikò, Bernardi, Paolo

“…The molecular identity of the mitochondrial megachannel (MMC)/permeability transition pore (PTP), a key effector of cell death, remains controversial. By…”
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Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets by Mooij, Petra, Koopman, Gerrit, Mortier, Daniëlla, van Heteren, Melanie, Oostermeijer, Herman, Fagrouch, Zahra, de Laat, Rudy, Kobinger, Gary, Li, Yan, Remarque, Edmond J, Kondova, Ivanela, Verschoor, Ernst J, Bogers, Willy M J M

“…The close immunological and physiological resemblance with humans makes non-human primates a valuable model for studying influenza virus pathogenesis and…”
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A low dose of RBD and TLR7/8 agonist displayed on influenza virosome particles protects rhesus macaque against SARS-CoV-2 challenge by Koopman, Gerrit, Amacker, Mario, Stegmann, Toon, Verschoor, Ernst J., Verstrepen, Babs E., Bhoelan, Farien, Bemelman, Denzel, Böszörményi, Kinga P., Fagrouch, Zahra, Kiemenyi-Kayere, Gwendoline, Mortier, Daniella, Verel, Dagmar E., Niphuis, Henk, Acar, Roja Fidel, Kondova, Ivanela, Kap, Yolanda S., Bogers, Willy M. J. M., Mooij, Petra, Fleury, Sylvain

“…Influenza virosomes serve as antigen delivery vehicles and pre-existing immunity toward influenza improves the immune responses toward antigens. Here, vaccine…”
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Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming by Scheeren, Ferenc A, van Bleek, Grada M, Spits, Hergen, Radbruch, Andreas, van Geelen, Caroline M M, Bakker, Arjen Q, Yasuda, Etsuko, Beaumont, Tim, Widjojoatmodjo, Myra N, Diehl, Sean A, Kwakkenbos, Mark J, Bogers, Willy M J M, Mei, Henrik, Lukens, Michaël V

“…Kwakkenbos et al . describe an in vitro method to generate antibody-secreting B cell lines from human peripheral blood memory B cells by transducing them with…”
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Potent Immune Responses in Rhesus Macaques Induced by Nonviral Delivery of a Self-amplifying RNA Vaccine Expressing HIV Type 1 Envelope With a Cationic Nanoemulsion by Bogers, Willy M., Oostermeijer, Herman, Mooij, Petra, Koopman, Gerrit, Verschoor, Ernst J., Davis, David, Ulmer, Jeffrey B., Brito, Luis A., Cu, Yen, Banerjee, Kaustuv, Otten, Gillis R., Burke, Brian, Dey, Antu, Heeney, Jonathan L., Shen, Xiaoying, Tomaras, Georgia D., Labranche, Celia, Montefiori, David C., Liao, Hua-Xin, Haynes, Barton, Geall, Andrew J., Barnett, Susan W.

“…Self-amplifying messenger RNA (mRNA) of positive-strand RNA viruses are effective vectors for in situ expression of vaccine antigens and have potential as a…”
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A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques by Volkmann, Ariane, Koopman, Gerrit, Mooij, Petra, Verschoor, Ernst J, Verstrepen, Babs E, Bogers, Willy M J M, Idorn, Manja, Paludan, Søren R, Vang, Søren, Nielsen, Morten A, Sander, Adam F, Schmittwolf, Carolin, Hochrein, Hubertus, Chaplin, Paul

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic. Here, we present non-human primate immunogenicity and protective…”
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Poxvirus MVA Expressing SARS-CoV-2 S Protein Induces Robust Immunity and Protects Rhesus Macaques From SARS-CoV-2 by Mooij, Petra, García-Arriaza, Juan, Pérez, Patricia, Lázaro-Frías, Adrian, Verstrepen, Babs E, Böszörményi, Kinga P, Mortier, Daniella, Fagrouch, Zahra, Kiemenyi-Kayere, Gwendoline, Niphuis, Henk, Acar, Roja Fidel, Meijer, Lisette, Stammes, Marieke A, Kondova, Ivanela, Verschoor, Ernst J, GeurtsvanKessel, Corine H, de Bruin, Erwin, Sikkema, Reina S, Luczkowiak, Joanna, Delgado, Rafael, Montenegro, Dolores, Puentes, Eugenia, Rodríguez, Esteban, Bogers, Willy M J M, Koopman, Gerrit, Esteban, Mariano

“…Novel safe, immunogenic, and effective vaccines are needed to control the COVID-19 pandemic, caused by SARS-CoV-2. Here, we describe the safety, robust…”
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Brain Inflammation and Intracellular α-Synuclein Aggregates in Macaques after SARS-CoV-2 Infection by Philippens, Ingrid H C H M, Böszörményi, Kinga P, Wubben, Jacqueline A M, Fagrouch, Zahra C, van Driel, Nikki, Mayenburg, Amber Q, Lozovagia, Diana, Roos, Eva, Schurink, Bernadette, Bugiani, Marianna, Bontrop, Ronald E, Middeldorp, Jinte, Bogers, Willy M, de Geus-Oei, Lioe-Fee, Langermans, Jan A M, Verschoor, Ernst J, Stammes, Marieke A, Verstrepen, Babs E

“…SARS-CoV-2 causes acute respiratory disease, but many patients also experience neurological complications. Neuropathological changes with pronounced…”
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Aerosolized Exposure to H5N1 Influenza Virus Causes Less Severe Disease Than Infection via Combined Intrabronchial, Oral, and Nasal Inoculation in Cynomolgus Macaques by Mooij, Petra, Stammes, Marieke A, Mortier, Daniella, Fagrouch, Zahra, van Driel, Nikki, Verschoor, Ernst J, Kondova, Ivanela, Bogers, Willy M J M, Koopman, Gerrit

“…Infection with highly pathogenic avian H5N1 influenza virus in humans often leads to severe respiratory disease with high mortality. Experimental infection in…”
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The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues by Böszörményi, Kinga P., Stammes, Marieke A., Fagrouch, Zahra C., Kiemenyi-Kayere, Gwendoline, Niphuis, Henk, Mortier, Daniella, van Driel, Nikki, Nieuwenhuis, Ivonne, Vervenne, Richard A. W., Haaksma, Tom, Ouwerling, Boudewijn, Adema, Deborah, Acar, Roja Fidel, Zuiderwijk-Sick, Ella, Meijer, Lisette, Mooij, Petra, Remarque, Ed J., Oostermeijer, Herman, Koopman, Gerrit, Hoste, Alexis C. R., Sastre, Patricia, Haagmans, Bart L., Bontrop, Ronald E., Langermans, Jan A. M., Bogers, Willy M., Kondova, Ivanela, Verschoor, Ernst J., Verstrepen, Babs E.

“…The post-acute phase of SARS-CoV-2 infection was investigated in rhesus (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis). During the acute phase…”
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Primary antibody response after influenza virus infection is first dominated by low-mutated HA-stem antibodies followed by higher-mutated HA-head antibodies by Aartse, Aafke, Mortier, Daniella, Mooij, Petra, Hofman, Sam, van Haaren, Marlies M., Corcoran, Martin, Karlsson Hedestam, Gunilla B., Eggink, Dirk, Claireaux, Mathieu, Bogers, Willy M. J. M., van Gils, Marit J., Koopman, Gerrit

“…Several studies have shown that the first encounter with influenza virus shapes the immune response to future infections or vaccinations. However, a detailed…”
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Vaccine-induced neutralizing antibody responses to seasonal influenza virus H1N1 strains are not enhanced during subsequent pandemic H1N1 infection by Mooij, Petra, Mortier, Daniella, Aartse, Aafke, Murad, Alexandre B., Correia, Ricardo, Roldão, António, Alves, Paula M., Fagrouch, Zahra, Eggink, Dirk, Stockhofe, Norbert, Engelhardt, Othmar G., Verschoor, Ernst J., van Gils, Marit J., Bogers, Willy M., Carrondo, Manuel J. T., Remarque, Edmond J., Koopman, Gerrit

“…The first exposure to influenza is presumed to shape the B-cell antibody repertoire, leading to preferential enhancement of the initially formed responses…”
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At the Epicenter of COVID-19-the Tragic Failure of the Global Supply Chain for Medical Supplies by Bhaskar, Sonu, Tan, Jeremy, Bogers, Marcel L A M, Minssen, Timo, Badaruddin, Hishamuddin, Israeli-Korn, Simon, Chesbrough, Henry

“…The tragic failure of the global supply chain in the face of the current coronavirus outbreak has caused acute shortages of essential frontline medical devices…”
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Cognitive Effects of Reducing First-Generation Antipsychotic Dose Compared to Switching to Ziprasidone in Long-Stay Patients with Schizophrenia by Bogers, Jan P A M, Blömer, Jasper A, de Haan, Lieuwe

“…Cognitive impairment is a core symptom of schizophrenia and is associated with functional outcomes. Improving cognitive function is an important treatment…”
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The significance of habitats as indicators of biodiversity and their links to species by Bunce, R.G.H., Bogers, M.M.B., Evans, D., Halada, L., Jongman, R.H.G., Mucher, C.A., Bauch, B., de Blust, G., Parr, T.W., Olsvig-Whittaker, L.

“…► Habitats can be direct policy indicators. ► Many taxa from different groups are associated with habitats. ► Consistent habitat mapping at a defined scale is…”
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Clozapine and COVID‐19 Vaccination: Effects on blood levels and leukocytes. An observational cohort study by Veerman, Selene R. T., Moscou, Timo, Bogers, Jan P. A. M., Cohen, Dan, Schulte, Peter F. J.

“…Objective To investigate the safety of COVID‐19 vaccination in patients on clozapine as regards plasma clozapine concentration and haematological parameters…”
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Influenza A Virus Hemagglutinin Trimer, Head and Stem Proteins Identify and Quantify Different Hemagglutinin-Specific B Cell Subsets in Humans by Aartse, Aafke, Eggink, Dirk, Claireaux, Mathieu, van Leeuwen, Sarah, Mooij, Petra, Bogers, Willy M, Sanders, Rogier W, Koopman, Gerrit, van Gils, Marit J

“…Antibody responses against the influenza A virus hemagglutinin (HA)-protein are studied intensively because they can protect against (re)infection. Previous…”
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Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence by Sliepen, Kwinten, Han, Byung Woo, Bontjer, Ilja, Mooij, Petra, Garces, Fernando, Behrens, Anna-Janina, Rantalainen, Kimmo, Kumar, Sonu, Sarkar, Anita, Brouwer, Philip J. M., Hua, Yuanzi, Tolazzi, Monica, Schermer, Edith, Torres, Jonathan L., Ozorowski, Gabriel, van der Woude, Patricia, de la Peña, Alba Torrents, van Breemen, Mariëlle J., Camacho-Sánchez, Juan Miguel, Burger, Judith A., Medina-Ramírez, Max, González, Nuria, Alcami, Jose, LaBranche, Celia, Scarlatti, Gabriella, van Gils, Marit J., Crispin, Max, Montefiori, David C., Ward, Andrew B., Koopman, Gerrit, Moore, John P., Shattock, Robin J., Bogers, Willy M., Wilson, Ian A., Sanders, Rogier W.

“…Stabilized HIV-1 envelope glycoproteins (Env) that resemble the native Env are utilized in vaccination strategies aimed at inducing broadly neutralizing…”
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Field identification of habitats directive Annex I habitats as a major European biodiversity indicator by Bunce, R.G.H., Bogers, M.M.B., Evans, D., Jongman, R.H.G.

“…► A hierarchical structure for the identification of Annex I habitats has been constructed using a defined series of habitat categories that can be…”
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EDITOR'S CHOICE: How much would it cost to monitor farmland biodiversity in Europe? by Geijzendorffer, Ilse R, Targetti, Stefano, Schneider, Manuel K, Brus, Dick J, Jeanneret, Philippe, Jongman, Robert H.G, Knotters, Martin, Viaggi, Davide, Angelova, Siyka, Arndorfer, Michaela, Bailey, Debra, Balázs, Katalin, Báldi, András, Bogers, Marion M. B, Bunce, Robert G. H, Choisis, Jean‐Philippe, Dennis, Peter, Eiter, Sebastian, Fjellstad, Wendy, Friedel, Jürgen K, Gomiero, Tiziano, Griffioen, Arjan, Kainz, Max, Kovács‐Hostyánszki, Anikó, Lüscher, Gisela, Moreno, Gerardo, Nascimbene, Juri, Paoletti, Maurizio G, Pointereau, Philippe, Sarthou, Jean‐Pierre, Siebrecht, Norman, Staritsky, Igor, Stoyanova, Siyka, Wolfrum, Sebastian, Herzog, Felix, Stephens, Phil

“…To evaluate progress on political biodiversity objectives, biodiversity monitoring provides information on whether intended results are being achieved. Despite…”
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