Search Results - "Bogers, Jan"
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1
Tapering antipsychotic medication: practical considerations
Published in Psychological medicine (01-01-2022)Get more information
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Beyond White Blood Cell Monitoring: Screening in the Initial Phase of Clozapine Therapy
Published in The journal of clinical psychiatry (01-10-2012)“…Clozapine is the preferred option for treatment-resistant schizophrenia. However, since 1975, clozapine has been known to cause agranulocytosis. In the…”
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Risk of clozapine-associated agranulocytosis and mandatory white blood cell monitoring: Can the regulations be relaxed?
Published in Schizophrenia research (01-06-2024)“…After the introduction of clozapine eight Finnish patients died after developing agranulocytosis. Clozapine was withdrawn from the market and only reintroduced…”
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Risk Factors for Psychotic Relapse After Dose Reduction or Discontinuation of Antipsychotics in Patients With Chronic Schizophrenia. A Meta-Analysis of Randomized Controlled Trials
Published in Schizophrenia bulletin (03-01-2023)“…Although maintenance treatment with antipsychotics protects against psychotic relapse, high doses may hamper recovery. Therefore, dose reduction or…”
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5
Recovery from leukopenia after discontinuation of clozapine does not exclude lymphoma
Published in Schizophrenia research (01-05-2024)Get full text
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Clozapine and COVID‐19 Vaccination: Effects on blood levels and leukocytes. An observational cohort study
Published in Acta psychiatrica Scandinavica (01-08-2022)“…Objective To investigate the safety of COVID‐19 vaccination in patients on clozapine as regards plasma clozapine concentration and haematological parameters…”
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Capillary compared to venous blood sampling in clozapine treatment: patients׳ and healthcare practitioners׳ experiences with a point-of-care device
Published in European neuropsychopharmacology (01-03-2015)“…Abstract Underuse of the antipsychotic clozapine for schizophrenia is an impediment to improving outcomes for patients. Because of its possible severe side…”
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Feasibility and Effect of Increasing Clozapine Plasma Levels in Long-Stay Patients With Treatment-Resistant Schizophrenia
Published in Journal of clinical psychopharmacology (01-03-2023)“…It is unknown whether increasing the clozapine plasma level to 400, 750, or even 1000 ng/mL is a feasible and effective strategy in patients with…”
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COVID-19: Risks, Complications, and Monitoring in Patients on Clozapine
Published in Pharmacopsychiatry (01-01-2022)“…The Dutch Clozapine Collaboration Group is frequently asked for advice about the management of clozapine-treated patients when infected with or vaccinated…”
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Clozapine Underutilization in the Treatment of Schizophrenia: How Can Clozapine Prescription Rates Be Improved?
Published in Journal of clinical psychopharmacology (01-04-2016)Get full text
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Cognitive Effects of Reducing First-Generation Antipsychotic Dose Compared to Switching to Ziprasidone in Long-Stay Patients with Schizophrenia
Published in Journal of clinical medicine (01-04-2024)“…Cognitive impairment is a core symptom of schizophrenia and is associated with functional outcomes. Improving cognitive function is an important treatment…”
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Interaction of St John’s wort (Hypericum perforatum) with clozapine
Published in International clinical psychopharmacology (01-03-2012)“…St John’s wort (Hypericum perforatum) is notorious for its ability to induce the enzymes of the P450 system. Especially, it induces CYP1A2 and CYP3A4, enzymes…”
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Oral contraceptives raise plasma clozapine concentrations
Published in Journal of clinical psychopharmacology (01-06-2014)Get full text
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Dose reduction of high-dose first-generation antipsychotics or switch to ziprasidone in long-stay patients with schizophrenia: A 1-year double-blind randomized clinical trial
Published in European neuropsychopharmacology (01-09-2018)“…Long-stay patients with severe schizophrenia are frequently treated with high doses of first-generation antipsychotics (FGA). Dose reduction or switching to…”
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The incidence and economic impact of aggression in closed long-stay psychiatric wards
Published in International journal of psychiatry in clinical practice (02-11-2021)“…Aggressive behaviour is highly prevalent in long-term psychiatric inpatient care. We aimed to estimate the overall incidence of aggression, the time staff took…”
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Effects of multivitamin, mineral and n-3 polyunsaturated fatty acid supplementation on aggression among long-stay psychiatric in-patients: randomised clinical trial
Published in BJPsych open (01-03-2022)“…Aggression and violent incidents are a major concern in psychiatric in-patient care. Nutritional supplementation has been found to reduce aggressive incidents…”
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Low levels of vitamin D poorly responsive to daylight exposure in patients with therapy-resistant schizophrenia
Published in Nordic journal of psychiatry (18-05-2016)“…Background: Low vitamin D levels are associated with schizophrenia, but the possible association between vitamin D levels and illness severity or duration of…”
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Clozapine and the risk of haematological malignancies
Published in The Lancet. Psychiatry (01-07-2022)Get full text
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Differences between physicians' and nurse practitioners' viewpoints on reasons for clozapine underprescription
Published in Brain and behavior (01-07-2019)“…Introduction Clozapine (CLZ) is the only proven effective therapy for treatment‐resistant schizophrenia, but it is underutilized across the globe. Previous…”
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Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts
Published in Translational psychiatry (27-09-2024)“…The second-generation antipsychotic clozapine is used as a medication for treatment-resistant schizophrenia. It has previously been associated with epigenetic…”
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