Search Results - "Bogdanove, Adam J."

TAL Effectors: Customizable Proteins for DNA Targeting by Bogdanove, Adam J., Voytas, Daniel F.

“…Generating and applying new knowledge from the wealth of available genomic information is hindered, in part, by the difficulty of altering nucleotide sequences…”
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Simple Cipher Governs DNA Recognition by TAL Effectors by Moscou, Matthew J, Bogdanove, Adam J

“…TAL effectors of plant pathogenic bacteria in the genus Xanthomonas bind host DNA and activate genes that contribute to disease or turn on defense. Target…”
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TAL effectors: finding plant genes for disease and defense by Bogdanove, Adam J, Schornack, Sebastian, Lahaye, Thomas

“…Transcription activator like effectors (TALEs) are injected via the type III secretion pathway of many plant pathogenic Xanthomonas spp. into plant cells where…”
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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting by Cermak, Tomas, Doyle, Erin L., Christian, Michelle, Wang, Li, Zhang, Yong, Schmidt, Clarice, Baller, Joshua A., Somia, Nikunj V., Bogdanove, Adam J., Voytas, Daniel F.

“…TALENs are important new tools for genome engineering. Fusions of transcription activator-like (TAL) effectors of plant pathogenic Xanthomonas spp. to the FokI…”
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TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction by Doyle, Erin L, Booher, Nicholas J, Standage, Daniel S, Voytas, Daniel F, Brendel, Volker P, Vandyk, John K, Bogdanove, Adam J

“…Transcription activator-like (TAL) effectors are repeat-containing proteins used by plant pathogenic bacteria to manipulate host gene expression. Repeats are…”
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Transcription Activator-Like Effector Nucleases Enable Efficient Plant Genome Engineering by Zhang, Yong, Zhang, Feng, Li, Xiaohong, Baller, Joshua A., Qi, Yiping, Starker, Colby G., Bogdanove, Adam J., Voytas, Daniel F.

“…The ability to precisely engineer plant genomes offers much potential for advancing basic and applied plant biology. Here, we describe methods for the targeted…”
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The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target by Mak, Amanda Nga-Sze, Bradley, Philip, Cernadas, Raul A., Bogdanove, Adam J., Stoddard, Barry L.

“…DNA recognition by TAL effectors is mediated by tandem repeats, each 33 to 35 residues in length, that specify nucleotides via unique repeat-variable…”
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Pathogenomics of Xanthomonas : understanding bacterium–plant interactions by Dow, J. Maxwell, Ryan, Robert P, Vorhölter, Frank-Jörg, Potnis, Neha, Jones, Jeffrey B, Van Sluys, Marie-Anne, Bogdanove, Adam J

“…Key Points Xanthomonas is a large genus of Gram-negative, yellow-pigmented bacteria that cause disease in nearly 400 plant hosts, including economically…”
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TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins by Doyle, Erin L, Stoddard, Barry L, Voytas, Daniel F, Bogdanove, Adam J

“…Highlights • Recent literature concerning transcription activator-like (TAL) effectors is reviewed. • TAL effectors are plant bacterial virulence factors that…”
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TAL effector driven induction of a SWEET gene confers susceptibility to bacterial blight of cotton by Cox, Kevin L., Meng, Fanhong, Wilkins, Katherine E., Li, Fangjun, Wang, Ping, Booher, Nicholas J., Carpenter, Sara C. D., Chen, Li-Qing, Zheng, Hui, Gao, Xiquan, Zheng, Yi, Fei, Zhangjun, Yu, John Z., Isakeit, Thomas, Wheeler, Terry, Frommer, Wolf B., He, Ping, Bogdanove, Adam J., Shan, Libo

“…Transcription activator-like (TAL) effectors from Xanthomonas citri subsp. malvacearum ( Xcm ) are essential for bacterial blight of cotton (BBC). Here, by…”
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A Reference Genome Sequence for Giant Sequoia by Scott, Alison D, Zimin, Aleksey V, Puiu, Daniela, Workman, Rachael, Britton, Monica, Zaman, Sumaira, Caballero, Madison, Read, Andrew C, Bogdanove, Adam J, Burns, Emily, Wegrzyn, Jill, Timp, Winston, Salzberg, Steven L, Neale, David B

“…Abstract The giant sequoia (Sequoiadendron giganteum) of California are massive, long-lived trees that grow along the U.S. Sierra Nevada mountains. Genomic…”
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Addition of transcription activator‐like effector binding sites to a pathogen strain‐specific rice bacterial blight resistance gene makes it effective against additional strains and against bacterial leaf streak by Hummel, Aaron W, Doyle, Erin L, Bogdanove, Adam J

“…• Xanthomonas transcription activator‐like (TAL) effectors promote disease in plants by binding to and activating host susceptibility genes. Plants counter…”
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TAL effectors: function, structure, engineering and applications by Mak, Amanda Nga-Sze, Bradley, Philip, Bogdanove, Adam J, Stoddard, Barry L

“…► TAL effectors are highly modular, easily programmable gene targeting proteins. ► Recent crystallographic analyses of TAL effectors have illustrated the basis…”
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Functional analysis of African Xanthomonas oryzae pv. oryzae TALomes reveals a new susceptibility gene in bacterial leaf blight of rice by Tran, Tuan T, Pérez-Quintero, Alvaro L, Wonni, Issa, Carpenter, Sara C D, Yu, Yanhua, Wang, Li, Leach, Jan E, Verdier, Valérie, Cunnac, Sébastien, Bogdanove, Adam J, Koebnik, Ralf, Hutin, Mathilde, Szurek, Boris

“…Most Xanthomonas species translocate Transcription Activator-Like (TAL) effectors into plant cells where they function like plant transcription factors via a…”
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Host-Induced Gene Silencing in Barley Powdery Mildew Reveals a Class of Ribonuclease-Like Effectors by PLIEGO, Clara, NOWARA, Daniela, SCHWEIZER, Patrick, BINDSCHEDLER, Laurence V, SPANU, Pietro D, BONCIANI, Giulia, GHEORGHE, Dana M, RUO XU, SURANA, Priyanka, WHIGHAM, Ehren, NETTLETON, Dan, BOGDANOVE, Adam J, WISE, Roger P

“…Obligate biotrophic pathogens of plants must circumvent or counteract defenses to guarantee accommodation inside the host. To do so, they secrete a variety of…”
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The effect of increasing numbers of repeats on TAL effector DNA binding specificity by Rinaldi, Fabio C, Doyle, Lindsey A, Stoddard, Barry L, Bogdanove, Adam J

“…Transcription activator-like effectors (TALEs) recognize their DNA targets via tandem repeats, each specifying a single nucleotide base in a one-to-one…”
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Genome assembly and characterization of a complex zfBED-NLR gene-containing disease resistance locus in Carolina Gold Select rice with Nanopore sequencing by Read, Andrew C, Moscou, Matthew J, Zimin, Aleksey V, Pertea, Geo, Meyer, Rachel S, Purugganan, Michael D, Leach, Jan E, Triplett, Lindsay R, Salzberg, Steven L, Bogdanove, Adam J

“…Long-read sequencing facilitates assembly of complex genomic regions. In plants, loci containing nucleotide-binding, leucine-rich repeat (NLR) disease…”
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Arabidopsis and Brachypodium distachyon Transgenic Plants Expressing Aspergillus nidulans Acetylesterases Have Decreased Degree of Polysaccharide Acetylation and Increased Resistance to Pathogens by Pogorelko, Gennady, Lionetti, Vincenzo, Fursova, Oksana, Sundaram, Raman M., Qi, Mingsheng, Whitham, Steven A., Bogdanove, Adam J., Bellincampi, Daniela, Zabotina, Olga A.

“…The plant cell wall has many significant structural and physiological roles, but the contributions of the various components to these roles remain unclear…”
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TAL effectors and activation of predicted host targets distinguish Asian from African strains of the rice pathogen Xanthomonas oryzae pv. oryzicola while strict conservation suggests universal importance of five TAL effectors by Wilkins, Katherine E, Booher, Nicholas J, Wang, Li, Bogdanove, Adam J

“…Xanthomonas oryzae pv. oryzicola (Xoc) causes the increasingly important disease bacterial leaf streak of rice (BLS) in part by type III delivery of…”
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Code-assisted discovery of TAL effector targets in bacterial leaf streak of rice reveals contrast with bacterial blight and a novel susceptibility gene by Cernadas, Raul A, Doyle, Erin L, Niño-Liu, David O, Wilkins, Katherine E, Bancroft, Timothy, Wang, Li, Schmidt, Clarice L, Caldo, Rico, Yang, Bing, White, Frank F, Nettleton, Dan, Wise, Roger P, Bogdanove, Adam J

“…Bacterial leaf streak of rice, caused by Xanthomonas oryzae pv. oryzicola (Xoc) is an increasingly important yield constraint in this staple crop. A mesophyll…”
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