Search Results - "Bogdanov, Alexei A."

Molecular Magnetic Resonance Imaging of Aneurysmal Inflammation Using a Redox Active Iron Complex by King, Robert M., Gounis, Matthew J., Schmidt, Eric J., Leporati, Anita, Gale, Eric M., Bogdanov, Alexei A.

“…Inflammation plays a key role in driving brain aneurysmal instability and rupture, but clinical tools to noninvasively differentiate between inflamed and…”
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Surface modification of neurovascular stents: from bench to patient by Zoppo, Christopher T, Mocco, J, Manning, Nathan W, Bogdanov, Jr, Alexei A, Gounis, Matthew J

“…Flow-diverting stents (FDs) for the treatment of cerebrovascular aneurysms are revolutionary. However, these devices require systemic dual antiplatelet therapy…”
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Antiretroviral Hydrophobic Core Graft-Copolymer Nanoparticles: The Effectiveness against Mutant HIV-1 Strains and in Vivo Distribution after Topical Application by Leporati, Anita, Gupta, Suresh, Bolotin, Elijah, Castillo, Gerardo, Alfaro, Joshua, Gottikh, Marina B., Bogdanov Jr, Alexei A.

“…Purpose Developing and testing of microbicides for pre-exposure prophylaxis and post-exposure protection from HIV are on the list of major HIV/AIDS research…”
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X‑ray Attenuating Vesicles with Neutrophil Extracellular Trap (NET) Specificity: Synthesis and Testing in a Model System by Epshtein, Mark, Gounis, Matthew J., Bogdanov, Alexei A.

“…X-ray attenuating contrast agents for imaging thrombi directly during endovascular thrombectomy (EVT) are urgently needed for shortening the wait time for…”
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Imaging NF‐κB activity in a murine model of early stage diabetes by Taghian, Toloo, Metelev, Valeriy G., Zhang, Surong, Bogdanov, Alexei A.

“…Early pro‐inflammatory signaling in the endocrine pancreas involves activation of NF‐κB, which is believed to be important for determining the ultimate fate of…”
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Human adipose–derived mesenchymal stem cells attenuate liver ischemia–reperfusion injury and promote liver regeneration by Saidi, Reza F., MD, Rajeshkumar, Barur, PhD, Shariftabrizi, Ahmad, MD, Bogdanov, Alexei A., PhD, Zheng, Shaokuan, PhD, Dresser, Karen, MS, Walter, Otto, MD

“…Background Ischemia-reperfusion injury (IRI) of the liver is a well-known cause of morbidity and mortality after liver transplantation. Effective treatment…”
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Synthesis and applications of theranostic oligonucleotides carrying multiple fluorine atoms by Metelev, Valeriy G, Bogdanov, Jr, Alexei A

“…The use of various oligonucleotide (ON) syntheses and post-synthetic strategies for targeted chemical modification enables improving their efficacy as potent…”
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Gold Nanoparticles Stabilized with MPEG-Grafted Poly(l‑lysine): in Vitro and in Vivo Evaluation of a Potential Theranostic Agent by Bogdanov, Alexei A, Gupta, Suresh, Koshkina, Nadezhda, Corr, Stuart J, Zhang, Surong, Curley, Steven A, Han, Gang

“…As the number of diagnostic and therapeutic applications utilizing gold nanoparticles (AuNPs) increases, so does the need for AuNPs that are stable in vivo,…”
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MR and fluorescence imaging of gadobutrol‐induced optical clearing of red fluorescent protein signal in an in vivo cancer model by Kazachkina, Natalia I., Zherdeva, Victoria V., Meerovich, Irina G., Saydasheva, Asiya N., Solovyev, Ilya D., Tuchina, Daria K., Savitsky, Alexander P., Tuchin, Valery V., Bogdanov, Alexei A.

“…Multimodality registration of optical and MR images in the same tissue volume in vivo may be enabled by MR contrast agents with an optical clearing (OC)…”
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Characterization of optical clearing mechanisms in muscle during treatment with glycerol and gadobutrol solutions by Silva, Hugo F., Martins, Inês S., Bogdanov, Alexei A., Tuchin, Valery V., Oliveira, Luís M.

“…The recent increasing interest in the application of radiology contrasting agents to create transparency in biological tissues implies that the diffusion…”
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In situ decellularization of a large animal saccular aneurysm model: sustained inflammation and active aneurysm wall remodeling by King, Robert M, Caroff, Jildaz, Langan, Erin T, Leporati, Anita, Rodriguez-Rodriguez, Aurora, Raskett, Christopher M, Gupta, Suresh, Puri, Ajit S, Caravan, Peter, Gounis, Matthew J, Bogdanov, Jr, Alexei A

“…To investigate in situ decellularization of a large animal model of saccular aneurysm as a strategy for achieving aneurysmal growth and lasting inflammation…”
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High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease by Wadghiri, Youssef Z., Hoang, Dung Minh, Leporati, Anita, Gounis, Matthew J., Rodríguez-Rodríguez, Aurora, Mazzanti, Mary L., Weaver, John P., Wakhloo, Ajay K., Caravan, Peter, Bogdanov, Alexei A.

“…Progress in clinical development of magnetic resonance imaging (MRI) substrate-sensors of enzymatic activity has been slow partly due to the lack of human…”
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Magnetic resonance contrast agents in optical clearing: Prospects for multimodal tissue imaging by Tuchina, Daria K., Meerovich, Irina G., Sindeeva, Olga A., Zherdeva, Victoria V., Savitsky, Alexander P., Bogdanov, Alexei A., Tuchin, Valery V.

“…Skin optical clearing effect ex vivo and in vivo was achieved by topical application of low molecular weight paramagnetic magnetic resonance contrast agents…”
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Myeloperoxidase in Human Intracranial Aneurysms: Preliminary Evidence by Gounis, Matthew J, Vedantham, Srinivasan, Weaver, John P, Puri, Ajit S, Brooks, Christopher S, Wakhloo, Ajay K, Bogdanov, Alexei A

“…BACKGROUND AND PURPOSE—Noninvasive imaging identifying a predictive biomarker of the bleeding risk of unruptured intracranial aneurysms (UIAs) is needed. We…”
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Synthesis and Testing of Modular Dual-Modality Nanoparticles for Magnetic Resonance and Multispectral Photoacoustic Imaging by Bogdanov, Alexei A, Dixon, Adam J, Gupta, Suresh, Zhang, Lejie, Zheng, Shaokuan, Shazeeb, Mohammed S, Zhang, Surong, Klibanov, Alexander L

“…Magnetic resonance (MR) and photoacoustic (PA) imaging are currently being investigated as complementing strategies for applications requiring sensitive…”
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Protected Graft Copolymer (PGC) in Imaging and Therapy: A Platform for the Delivery of Covalently and Non-Covalently Bound Drugs by Bogdanov, Jr, Alexei A, Mazzanti, Mary, Castillo, Gerardo, Bolotin, Elijah

“…Initially developed in 1992 as an MR imaging agent, the family of protected graft copolymers (PGC) is based on a conjugate of polylysine backbone to which…”
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Aneurysm permeability following coil embolization: packing density and coil distribution by Chueh, Ju-Yu, Vedantham, Srinivasan, Wakhloo, Ajay K, Carniato, Sarena L, Puri, Ajit S, Bzura, Conrad, Coffin, Spencer, Bogdanov, Jr, Alexei A, Gounis, Matthew J

“…Rates of durable aneurysm occlusion following coil embolization vary widely, and a better understanding of coil mass mechanics is desired. The goal of this…”
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Dual radiosensitization and anti-STAT3 anti-proliferative strategy based on delivery of gold nanoparticle - oligonucleotide nanoconstructs to head and neck cancer cells by Zhang, Surong, Gupta, Suresh, Fitzgerald, Thomas J, Bogdanov, Jr, Alexei A

“…Constitutively activated signal transducer and activator of transcription 3 (STAT3) factor is an important therapeutic target in head and neck cancer (HNC)…”
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Dynamic monitoring of blood-brain barrier integrity using water exchange index (WEI) during mannitol and CO2 challenges in mouse brain by Huang, Shuning, Farrar, Christian T., Dai, Guangping, Kwon, Seon Joo, Bogdanov Jr, Alexei A., Rosen, Bruce R., Kim, Young R.

“…The integrity of the blood–brain barrier (BBB) is critical to normal brain function. Traditional techniques for the assessment of BBB disruption rely heavily…”
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Merging molecular imaging and RNA interference: Early experience in live animals by Bogdanov Jr, Alexei A.

“…The rapid development of non‐invasive imaging techniques and imaging reporters coincided with the enthusiastic response that the introduction of RNA…”
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