Search Results - "Bogdani, Marika"

Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes by Korpos, Éva, Kadri, Nadir, Loismann, Sophie, Findeisen, Clais R., Arfuso, Frank, Burke, George W., Richardson, Sarah J., Morgan, Noel G., Bogdani, Marika, Pugliese, Alberto, Sorokin, Lydia

“…Aims/hypothesis We and others previously reported the presence of tertiary lymphoid organs (TLOs) in the pancreas of NOD mice, where they play a role in the…”
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Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet by Di Fulvio, Mauricio, Bogdani, Marika, Velasco, Myrian, McMillen, Timothy S, Ridaura, Cecilia, Kelly, Lisa, Almutairi, Mohammed M, Kursan, Shams, Sajib, Abu A, Hiriart, Marcia, Aguilar-Bryan, Lydia

“…Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator (CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity,…”
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Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates by Bogdani, Marika, Speake, Cate, Dufort, Mathew J., Johnson, Pamela Y., Larmore, Megan J., Day, Anthony J., Wight, Thomas N., Lernmark, Åke, Greenbaum, Carla J.

“…Aims/hypothesis Substantial deposition of the extracellular matrix component hyaluronan (HA) is characteristic of insulitis in overt type 1 diabetes. We…”
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Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis by Nagy, Nadine, Kaber, Gernot, Johnson, Pamela Y, Gebe, John A, Preisinger, Anton, Falk, Ben A, Sunkari, Vivekananda G, Gooden, Michel D, Vernon, Robert B, Bogdani, Marika, Kuipers, Hedwich F, Day, Anthony J, Campbell, Daniel J, Wight, Thomas N, Bollyky, Paul L

“…We recently reported that abundant deposits of the extracellular matrix polysaccharide hyaluronan (HA) are characteristic of autoimmune insulitis in patients…”
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The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats by Bogdani, Marika, Faxius, Linda, Fex, Malin, Ramelius, Anita, Wernersson, Anya, Mordes, John P., Blankenhorn, Elizabeth P., Lernmark, Åke

“…The depleting Vβ13a T cell receptor monoclonal antibody (mAb) 17D5 prevents both induced and spontaneous autoimmune diabetes in BB rats. Here it was tested in…”
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Can CD44 Be a Mediator of Cell Destruction? The Challenge of Type 1 Diabetes by Assayag-Asherie, Nathalie, Sever, Dror, Bogdani, Marika, Johnson, Pamela, Weiss, Talya, Ginzberg, Ariel, Perles, Sharon, Weiss, Lola, Sebban, Lora Eshkar, Turley, Eva A, Okon, Elimelech, Raz, Itamar, Naor, David

“…CD44 is a multi-functional receptor with multiple of isoforms engaged in modulation of cell trafficking and transmission of apoptotic signals. We have…”
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The Role of Hyaluronan and the Extracellular Matrix in Islet Inflammation and Immune Regulation by Bollyky, Paul L., Bogdani, Marika, Bollyky, Jennifer B., Hull, Rebecca L., Wight, Thomas N.

“…Type 1 diabetes (T1D) is a disease that in most individuals results from autoimmune attack of a single tissue type, the pancreatic islet. A fundamental,…”
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Correlation between β Cell Mass and Glycemic Control in Type 1 Diabetic Recipients of Islet Cell Graft by Keymeulen, Bart, Gillard, Pieter, Mathieu, Chantal, Movahedi, Babak, Maleux, Geert, Delvaux, Georges, Ysebaert, Dirk, Roep, Bart, Vandemeulebroucke, Evy, Marichal, Miriam, In 't Veld, Peter, Bogdani, Marika, Hendrieckx, Christel, Gorus, Frans, Ling, Zhidong, van Rood, Jon, Pipeleers, Daniel

“…Islet grafts can induce insulin independence in type 1 diabetic patients, but their function is variable with only 10% insulin indepence after 5 years. We…”
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Thinking Outside the Cell: A Key Role for Hyaluronan in the Pathogenesis of Human Type 1 Diabetes by Bogdani, Marika

“…Studies in pancreata from patients with type 1 diabetes have revealed the presence of insulitis, identified histologically as immune cell infiltrates around…”
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Intrahepatic Glucose Flux as a Mechanism for Defective Intrahepatic Islet α-Cell Response to Hypoglycemia by Zhou, Huarong, Zhang, Tao, Bogdani, Marika, Oseid, Elizabeth, Parazzoli, Susan, Vantyghem, Marie-Christine, Harmon, Jamie, Slucca, Michela, Robertson, R Paul

“…Intrahepatic Glucose Flux as a Mechanism for Defective Intrahepatic Islet α-Cell Response to Hypoglycemia Huarong Zhou 1 , Tao Zhang 1 , Marika Bogdani 1 ,…”
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Growth and Functional Maturation of β-Cells in Implants of Endocrine Cells Purified From Prenatal Porcine Pancreas by Bogdani, Marika, Suenens, Krista, Bock, Troels, Pipeleers-Marichal, Miriam, In't Veld, Peter, Pipeleers, Daniel

“…Growth and Functional Maturation of β-Cells in Implants of Endocrine Cells Purified From Prenatal Porcine Pancreas Marika Bogdani 1 , Krista Suenens 1 , Troels…”
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Heterogenous neuropathology in a pedigree with RAB39B-related Parkinson’s disease (P8-11.004) by Su, Kimmy, Latimer, Caitlin, Bogdani, Marika, Keene, Dirk, Zabetian, Cyrus

“…Abstract only…”
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Correction: Heterogeneous expression of CFTR in insulin-secreting [beta]-cells of the normal human islet by Fulvio, Mauricio Di, Bogdani, Marika, Velasco, Myrian, McMillen, Timothy S, Ridaura, Cecilia, Kelly, Lisa, Almutairi, Mohammed M, Kursan, Shams, Sajib, Abu A, Hiriart, Marcia, Aguilar-Bryan, Lydia

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Structural abnormalities in islets from very young children with cystic fibrosis may contribute to cystic fibrosis-related diabetes by Bogdani, Marika, Blackman, Scott M., Ridaura, Cecilia, Bellocq, Jean-Pierre, Powers, Alvin C., Aguilar-Bryan, Lydia

“…Cystic fibrosis (CF)-related diabetes (CFRD) is thought to result from beta-cell injury due in part to pancreas exocrine damage and lipofibrosis. CFRD…”
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Hyaluronan and Hyaluronan-Binding Proteins Accumulate in Both Human Type 1 Diabetic Islets and Lymphoid Tissues and Associate With Inflammatory Cells in Insulitis by BOGDANI, Marika, JOHNSON, Pamela Y, POTTER-PERIGO, Susan, NAGY, Nadine, DAY, Anthony J, BOLLYKY, Paul L, WIGHT, Thomas N

“…Hyaluronan (HA) is an extracellular matrix glycosaminoglycan that is present in pancreatic islets, but little is known about its involvement in the development…”
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Restoring the balance in autoimmunity: the promise of IL-2 mutein by Khoryati, Liliane, Pham, Minh Nguyet, Sherve, McKenna, Kumari, Swarnima, Bogdani, Marika, Campbell, Daniel J., Gavin, Marc

“…Abstract The development and function of regulatory T cells (Treg) relies on interleukin-2 (IL-2), and Treg efficiently compete with other cells for IL-2 by…”
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MP62-20 LOCALIZATION AND EXPRESSION OF EXTRACELLULAR MATRIX COMPONENTS VERSICAN AND HYALURONAN IN URETHRAL AND VAGINAL TISSUES IN HUMAN SPECIMENS AND IN RAT MODEL OF URINARY INCONTINENCE by Harten, Ingrid, Evanko, Stephen, Choe, Jay, Lee, Eugene, Bogdani, Marika, Wight, Thomas, Lee, Una

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An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice by Khoryati, Liliane, Pham, Minh Nguyet, Sherve, McKenna, Kumari, Swarnima, Cook, Kevin, Pearson, Josh, Bogdani, Marika, Campbell, Daniel J, Gavin, Marc A

“…Interleukin-2 (IL-2) controls the homeostasis and function of regulatory T (T ) cells, and defects in the IL-2 pathway contribute to multiple autoimmune…”
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Selectively Agonizing Treg in Type 1 Diabetes with IL-2 Muteins by KHORYATI, LILIANE, KUMARI, SWARNIMA, NGUYET PHAM, THI MINH, BOGDANI, MARIKA, GAVIN, MARC

“…Regulatory T cells (Treg) play a pivotal role in maintaining self-tolerance. For their development and function, Treg rely on interleukin-2 (IL-2) and…”
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Detection of Glycosaminoglycans in Pancreatic Islets and Lymphoid Tissues by Bogdani, Marika, Simeonovic, Charmaine, Nagy, Nadine, Johnson, Pamela Y, Chan, Christina K, Wight, Thomas N

“…In this chapter, we describe the detection of the glycosaminoglycans hyaluronan and heparan sulfate in pancreatic islets and lymphoid tissues. The…”
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