Search Results - "Bogdan, Christian"

Nitric oxide synthase in innate and adaptive immunity: an update by Bogdan, Christian

“…Highlights • In addition to its regulation by cytokines, NOS2 is modulated by micromilieu factors. • NOS2-derived NO controls pathogens by restricting their…”
Get full text

Macrophages as host, effector and immunoregulatory cells in leishmaniasis: Impact of tissue micro-environment and metabolism by Bogdan, Christian

“…•Macrophages serve as replicative niche, antimicrobial effectors or immunoregulators.•Functional diversity results from cytokines, micromilieu factors and…”
Get full text

Effectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis by Falkenhorst, Gerhard, Remschmidt, Cornelius, Harder, Thomas, Hummers-Pradier, Eva, Wichmann, Ole, Bogdan, Christian

“…Routine vaccination of elderly people against pneumococcal diseases is recommended in many countries. National guidelines differ, recommending either the…”
Get full text

Function of Macrophage and Parasite Phosphatases in Leishmaniasis by Soulat, Didier, Bogdan, Christian

“…The kinetoplastid protozoan parasites belonging to the genus are the causative agents of different clinical forms of leishmaniasis, a vector-borne infectious…”
Get full text

Nitric oxide and the regulation of gene expression by Bogdan, Christian

“…During the past 15 years, nitric oxide (NO) and NO synthases have become an important research topic in cellular and molecular biology. NO is produced by many…”
Get full text

Safety and effectiveness of acellular pertussis vaccination during pregnancy: a systematic review by Vygen-Bonnet, Sabine, Hellenbrand, Wiebke, Garbe, Edeltraut, von Kries, Rüdiger, Bogdan, Christian, Heininger, Ulrich, Röbl-Mathieu, Marianne, Harder, Thomas

“…Infants < 3 months of age are at highest risk for developing severe complications after pertussis. The majority of pregnant women has low concentrations of…”
Get full text

Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense by Jantsch, Jonathan, Schatz, Valentin, Friedrich, Diana, Schröder, Agnes, Kopp, Christoph, Siegert, Isabel, Maronna, Andreas, Wendelborn, David, Linz, Peter, Binger, Katrina J., Gebhardt, Matthias, Heinig, Matthias, Neubert, Patrick, Fischer, Fabian, Teufel, Stefan, David, Jean-Pierre, Neufert, Clemens, Cavallaro, Alexander, Rakova, Natalia, Küper, Christoph, Beck, Franz-Xaver, Neuhofer, Wolfgang, Muller, Dominik N., Schuler, Gerold, Uder, Michael, Bogdan, Christian, Luft, Friedrich C., Titze, Jens

“…Immune cells regulate a hypertonic microenvironment in the skin; however, the biological advantage of increased skin Na+ concentrations is unknown. We found…”
Get full text

Influence of different treatment conditions on the filtration performance of conventional electret melt blown non-woven and novel nano FFP2 masks by Halamicek, Robin, Wiesmann, Carolin, Kröner, Richard, Eber, Matthias, Bogdan, Christian, Schubert, Dirk W

“…To allow an efficient protection against viruses like the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), it is important to avoid their…”
Get full text

Arginase impedes the resolution of colitis by altering the microbiome and metabolome by Baier, Julia, Gänsbauer, Maximilian, Giessler, Claudia, Arnold, Harald, Muske, Mercedes, Schleicher, Ulrike, Lukassen, Sören, Ekici, Arif, Rauh, Manfred, Daniel, Christoph, Hartmann, Arndt, Schmid, Benjamin, Tripal, Philipp, Dettmer, Katja, Oefner, Peter J, Atreya, Raja, Wirtz, Stefan, Bogdan, Christian, Mattner, Jochen

“…Arginase 1 (Arg1), which converts l-arginine into ornithine and urea, exerts pleiotropic immunoregulatory effects. However, the function of Arg1 in…”
Get full text

Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection by Nairz, Manfred, Schleicher, Ulrike, Schroll, Andrea, Sonnweber, Thomas, Theurl, Igor, Ludwiczek, Susanne, Talasz, Heribert, Brandacher, Gerald, Moser, Patrizia L, Muckenthaler, Martina U, Fang, Ferric C, Bogdan, Christian, Weiss, Günter

“…Nitric oxide (NO) generated by inducible NO synthase 2 (NOS2) affects cellular iron homeostasis, but the underlying molecular mechanisms and implications for…”
Get full text

Effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly: a systematic review by Remschmidt, Cornelius, Harder, Thomas, Wichmann, Ole, Bogdan, Christian, Falkenhorst, Gerhard

“…In many industrialized countries routine vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) is recommended to prevent pneumococcal…”
Get full text

The function of type I interferons in antimicrobial immunity by Bogdan, Christian

“…Type I interferons (IFN-α and IFN-β) were originally described as potent antiviral substances, which are produced upon infection of animal cells with viruses…”
Get full text

TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis by Liese, Jan, Schleicher, Ulrike, Bogdan, Christian

“…Mice deficient for the TLR adaptor molecule MyD88 succumb to a local infection with Leishmania (L.) major. However, the TLR(s) that contribute to the control…”
Get full text

TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection by Schleicher, Ulrike, Paduch, Katrin, Debus, Andrea, Obermeyer, Stephanie, König, Till, Kling, Jessica C., Ribechini, Eliana, Dudziak, Diana, Mougiakakos, Dimitrios, Murray, Peter J., Ostuni, Renato, Körner, Heinrich, Bogdan, Christian

“…Neutralization or deletion of tumor necrosis factor (TNF) causes loss of control of intracellular pathogens in mice and humans, but the underlying mechanisms…”
Get full text

Mucocutaneous Leishmaniasis due to Leishmania infantum Infection by Linse, Kai-Philipp, Bogdan, Christian, Haenssle, Holger A, Toberer, Ferdinand

“…Abstract is missing (Short communcation)…”
Get full text

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens by Qualls, Joseph E, Pesce, John T, Tuomanen, Elaine I, Orme, Ian M, Murray, Peter J, Kanneganti, Thirumala-Devi, Fitzgerald, Katherine A, Kaplan, Gilla, König, Till, Henao-Tamayo, Marcela, Schleicher, Ulrike, Bogdan, Christian, Koo, Mi-Sun, Basaraba, Randall J, Smith, Amber M, Wynn, Thomas A, El Kasmi, Karim C, Thompson, Robert W

“…Classically activated macrophages are targets of intracellular bacteria such as Mycobacteria tuberculosis . Murray and colleagues find that such pathogens…”
Get full text

Whole-genome analysis of vancomycin-resistant Enterococcus faecium causing nosocomial outbreaks suggests the occurrence of few endemic clonal lineages in Bavaria, Germany by Eisenberger, David, Tuschak, Christian, Werner, Markus, Bogdan, Christian, Bollinger, Thomas, Hossain, Hamid, Friedrich, Petra, Hussein, Ziyad, Pöhlmann, Christoph, Würstl, Benjamin, Nickel, Silke, Lehner-Reindl, Verena, Höller, Christiane, Liebl, Bernhard, Valenza, Giuseppe

“…Infections caused by vancomycin-resistant Enterococcus faecium (VREfm) represent a major public health concern due to limited treatment options. Among invasive…”
Get full text

High Frequency of Tropheryma whipplei in Culture-Negative Endocarditis by GEISSDÖRFER, Walter, MOOS, Verena, SCHNEIDER, Thomas, MOTER, Annette, LODDENKEMPER, Christoph, JANSEN, Andreas, TANDLER, René, MORGUET, Andreas J, FENOLLAR, Florence, RAOULT, Didier, BOGDAN, Christian

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells by Straub, Tobias, Freudenberg, Marina A., Schleicher, Ulrike, Bogdan, Christian, Gasteiger, Georg, Pircher, Hanspeter

“…Infection of specific pathogen-free mice with lymphocytic choriomeningitis virus (LCMV) is a widely used model to study antiviral T-cell immunity. Infections…”
Get full text

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells by Lotz, Michael, Gütle, Dominique, Walther, Sabrina, Ménard, Sandrine, Bogdan, Christian, Hornef, Mathias W

“…The role of innate immune recognition by intestinal epithelial cells (IECs) in vivo is ill-defined. Here, we used highly enriched primary IECs to analyze…”
Get full text