Search Results - "Bogatcheva, Natalia V."

The role of cytoskeleton in the regulation of vascular endothelial barrier function by Bogatcheva, Natalia V., Verin, Alexander D.

“…The cytoskeleton is vital to the function of virtually all cell types in the organism as it is required for cell division, cell motility, endo- or exocytosis…”
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Concentrated Secretome of Adipose Stromal Cells Limits Influenza A Virus-Induced Lung Injury in Mice by Bogatcheva, Natalia V, Coleman, Michael E

“…Despite vaccination and antivirals, influenza remains a communicable disease of high burden, with limited therapeutic options available to patients that…”
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Pulmonary Retention of Adipose Stromal Cells Following Intravenous Delivery Is Markedly Altered in the Presence of ARDS by Lu, Hongyan, Cook, Todd, Poirier, Christophe, Merfeld-Clauss, Stephanie, Petrache, Irina, March, Keith L, Bogatcheva, Natalia V

“…Transplantation of mesenchymal stromal cells (MSCs) has been shown to effectively prevent lung injury in several preclinical models of acute respiratory…”
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Relaxin Promotes Prostate Cancer Progression by SHU FENG, AGOULNIK, Irina U, BOGATCHEVA, Natalia V, KAMAT, Aparna A, KWABI-ADDO, Bernard, LI, Rile, AYALA, Gustavo, ITTMANN, Michael M, AGOULNIK, Alexander I

“…Purpose: To understand the role of relaxin peptide in prostate cancer, we analyzed the expression of relaxin and its receptor in human prostate cancer samples,…”
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Distinct Factors Secreted by Adipose Stromal Cells Protect the Endothelium From Barrier Dysfunction and Apoptosis by Lu, Hongyan, Merfeld-Clauss, Stephanie, Jawed, Yameena, March, Keith L., Coleman, Michael E., Bogatcheva, Natalia V.

“…We have shown previously that adipose stromal cell (ASC)-derived conditioned media (CM) limited lung injury, endothelial barrier dysfunction, and apoptosis…”
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GREAT/LGR8 Is the Only Receptor for Insulin-Like 3 Peptide by Bogatcheva, Natalia V, Truong, Anne, Feng, Shu, Engel, Wolfgang, Adham, Ibrahim M, Agoulnik, Alexander I

“…During male development testes descend from their embryonic intraabdominal position into the scrotum. Two genes, encoding the insulin-like 3 peptide (INSL3)…”
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Genetic Targeting of Relaxin and Insulin-Like Factor 3 Receptors in Mice by Kamat, Aparna A, Feng, Shu, Bogatcheva, Natalia V, Truong, Anne, Bishop, Colin E, Agoulnik, Alexander I

“…Relaxin (RLN) is a small peptide hormone that affects a variety of biological processes. Rln1 knockout mice exhibit abnormal nipple development, prolonged…”
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Developmental Expression and Gene Regulation of Insulin-like 3 Receptor RXFP2 in Mouse Male Reproductive Organs by Feng, Shu, Bogatcheva, Natalia V, Truong, Anne, Korchin, Borys, Bishop, Colin E, Klonisch, Thomas, Agoulnik, Irina U, Agoulnik, Alexander I

“…The mutations of testicular insulin-like 3 (INSL3) hormone or its receptor RXFP2 cause cryptorchidism in male mice. Here we have examined Rxfp2 gene expression…”
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TIMAP is a positive regulator of pulmonary endothelial barrier function by Csortos, Csilla, Czikora, Istvan, Bogatcheva, Natalia V, Adyshev, Djanybek M, Poirier, Christophe, Olah, Gabor, Verin, Alexander D

“…TGF-beta-inhibited membrane-associated protein, TIMAP, is expressed at high levels in endothelial cells (EC). It is regarded as a member of the MYPT (myosin…”
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The role of relaxin in endometrial cancer by Kamat, Aparna A., Feng, Shu, Agoulnik, Irina U., Kheradmand, Farrah, Bogatcheva, Natalia V., Coffey, Donna, Sood, Anil K., Agoulnik, Alexander I.

“…Relaxin (RLN) is a naturally occurring hormone that is known to modulate connective tissue remodeling in the uterus and cervix. Our goal was to investigate the…”
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EMAPII Monoclonal Antibody Ameliorates Influenza A Virus-Induced Lung Injury by Lu, Hongyan, Chelvanambi, Sarvesh, Poirier, Christophe, Saliba, Jacob, March, Keith L., Clauss, Matthias, Bogatcheva, Natalia V.

“…Influenza A virus (IAV) remains a major worldwide health threat, especially to high-risk populations, including the young and elderly. There is an unmet…”
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HIV-Nef Protein Persists in the Lungs of Aviremic Patients with HIV and Induces Endothelial Cell Death by Chelvanambi, Sarvesh, Bogatcheva, Natalia V, Bednorz, Mariola, Agarwal, Stuti, Maier, Bernhard, Alves, Nathan J, Li, Wei, Syed, Farooq, Saber, Manal M, Dahl, Noelle, Lu, Hongyan, Day, Richard B, Smith, Patricia, Jolicoeur, Paul, Yu, Qigui, Dhillon, Navneet K, Weissmann, Norbert, Twigg Iii, Homer L, Clauss, Matthias

“…It remains a mystery why HIV-associated end-organ pathologies persist in the era of combined antiretroviral therapy (ART). One possible mechanism is the…”
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AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice by Barwinska, Daria, Oueini, Houssam, Poirier, Christophe, Albrecht, Marjorie E, Bogatcheva, Natalia V, Justice, Matthew J, Saliba, Jacob, Schweitzer, Kelly S, Broxmeyer, Hal E, March, Keith L, Petrache, Irina

“…We have shown that cigarette smoke (CS)-induced pulmonary emphysema-like manifestations are preceded by marked suppression of the number and function of bone…”
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Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability by Bogatcheva, Natalia V., Zemskova, Marina A., Kovalenkov, Yevgeniy, Poirier, Christophe, Verin, Alexander D.

“…Up to date, the nature of the sepsis‐induced vascular leakage is understood only partially, which limits pharmacological approaches for its management. Here we…”
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Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury by Aggarwal, Saurabh, Gross, Christine M, Kumar, Sanjiv, Dimitropoulou, Christiana, Sharma, Shruti, Gorshkov, Boris A, Sridhar, Supriya, Lu, Qing, Bogatcheva, Natalia V, Jezierska-Drutel, Agnieszka J, Lucas, Rudolf, Verin, Alexander D, Catravas, John D, Black, Stephen M

“…Acute lung injury (ALI) is a severe hypoxemic respiratory insufficiency associated with lung leak, diffuse alveolar damage, inflammation, and loss of lung…”
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Isolation and Expression Analysis of the Canine Insulin-Like Factor 3 Gene by TRUONG, Anne, BOGATCHEVA, Natalia V, SCHELLING, Claude, DOLF, Gaudenz, AGOULNIK, Alexander I

“…The insulin-like factor 3 (INSL3 or relaxin-like factor) is a hormone produced mainly in gonadal tissues in males and females. Deletion of INSL3 or its…”
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Phorbol esters increase MLC phosphorylation and actin remodeling in bovine lung endothelium without increased contraction by Bogatcheva, Natalia V, Verin, Alexander D, Wang, Peiyi, Birukova, Anna A, Birukov, Konstantin G, Mirzopoyazova, Tamara, Adyshev, Djanybek M, Chiang, Eddie T, Crow, Michael T, Garcia, Joe G N

“…Direct protein kinase C (PKC) activation with phorbol myristate acetate (PMA) results in the loss of endothelial monolayer integrity in bovine lung endothelial…”
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Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis by Lu, Hongyan, Poirier, Christophe, Cook, Todd, Traktuev, Dmitry O, Merfeld-Clauss, Stephanie, Lease, Benjamin, Petrache, Irina, March, Keith L, Bogatcheva, Natalia V

“…Acute Respiratory Distress Syndrome (ARDS) is a condition that contributes to morbidity and mortality of critically ill patients. We investigated whether…”
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The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier? by Bogatcheva, Natalia V., Zemskova, Marina A., Poirier, Christophe, Mirzapoiazova, Tamara, Kolosova, Irina, Bresnick, Anne R., Verin, Alexander D.

“…Sepsis‐induced vascular leakage is a major underlying cause of the respiratory dysfunction seen in severe sepsis. Here, we studied the role of MLC…”
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T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane by Bogatcheva, Natalia V, Ferlin, Alberto, Feng, Shu, Truong, Anne, Gianesello, Lisa, Foresta, Carlo, Agoulnik, Alexander I

“…Insulin-like 3 (INSL3) hormone plays a crucial role in testicular descent during embryonic development. Genetic ablation of Insl3 or its G protein-coupled…”
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