Search Results - "Bogachev, Sergey S"

The Molecular Aspects of Functional Activity of Macrophage-Activating Factor GcMAF by Kirikovich, Svetlana S, Levites, Evgeniy V, Proskurina, Anastasia S, Ritter, Genrikh S, Peltek, Sergey E, Vasilieva, Asya R, Ruzanova, Vera S, Dolgova, Evgeniya V, Oshihmina, Sofya G, Sysoev, Alexandr V, Koleno, Danil I, Danilenko, Elena D, Taranov, Oleg S, Ostanin, Alexandr A, Chernykh, Elena R, Kolchanov, Nikolay A, Bogachev, Sergey S

“…Group-specific component macrophage-activating factor (GcMAF) is the vitamin D -binding protein (DBP) deglycosylated at Thr . The protein is believed to…”
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The Macrophage Activator GcMAF-RF Enhances the Antitumor Effect of Karanahan Technology through Induction of M2–M1 Macrophage Reprogramming by Ruzanova, Vera S., Kirikovich, Svetlana S., Levites, Evgeniy V., Proskurina, Anastasia S., Dolgova, Evgeniya V., Ritter, Genrikh S., Efremov, Yaroslav R., Dubatolova, Tatyana D., Sysoev, Alexander V., Koleno, Danil I., Ostanin, Alexandr A., Chernykh, Elena R., Bogachev, Sergey S.

“…Macrophages are the immune cells of high-immunological plasticity, which can exert both pro- and anti-inflammatory activity, as well as repolarize their…”
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The New General Biological Property of Stem-like Tumor Cells (Part II: Surface Molecules, Which Belongs to Distinctive Groups with Particular Functions, Form a Unique Pattern Characteristic of a Certain Type of Tumor Stem-like Cells) by Petrova, Daria D, Dolgova, Evgeniya V, Proskurina, Anastasia S, Ritter, Genrikh S, Ruzanova, Vera S, Efremov, Yaroslav R, Potter, Ekaterina A, Kirikovich, Svetlana S, Levites, Evgeniy V, Taranov, Oleg S, Ostanin, Alexandr A, Chernykh, Elena R, Kolchanov, Nikolay A, Bogachev, Sergey S

“…An ability of poorly differentiated cells of different genesis, including tumor stem-like cells (TSCs), to internalize extracellular double-stranded DNA…”
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Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity by Dolgova, Evgeniya V, Kirikovich, Svetlana S, Levites, Evgeniy V, Ruzanova, Vera S, Proskurina, Anastasia S, Ritter, Genrikh S, Taranov, Oleg S, Varaksin, Nikolay A, Ryabicheva, Tatiana G, Leplina, Olga Yu, Ostanin, Alexandr A, Chernykh, Elena R, Bogachev, Sergey S

“…The main problem related to the studies focusing on group-specific component protein-derived macrophage-activating factor (GcMAF) is the lack of clarity about…”
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Impact of Double-Stranded RNA Internalization on Hematopoietic Progenitors and Krebs-2 Cells and Mechanism by Ritter, Genrikh S, Proskurina, Anastasia S, Meschaninova, Maria I, Potter, Ekaterina A, Petrova, Daria D, Ruzanova, Vera S, Dolgova, Evgeniya V, Kirikovich, Svetlana S, Levites, Evgeniy V, Efremov, Yaroslav R, Nikolin, Valeriy P, Popova, Nelly A, Venyaminova, Aliya G, Taranov, Oleg S, Ostanin, Alexandr A, Chernykh, Elena R, Kolchanov, Nikolay A, Bogachev, Sergey S

“…It is well-established that double-stranded RNA (dsRNA) exhibits noticeable radioprotective and radiotherapeutic effects. The experiments conducted in this…”
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Production of GcMAF with Anti-Inflammatory Properties and Its Effect on Models of Induced Arthritis in Mice and Cystitis in Rats by Kirikovich, Svetlana S, Levites, Evgeniy V, Proskurina, Anastasia S, Ritter, Genrikh S, Dolgova, Evgeniya V, Ruzanova, Vera S, Oshihmina, Sofya G, Snegireva, Julia S, Gamaley, Svetlana G, Sysoeva, Galina M, Danilenko, Elena D, Taranov, Oleg S, Ostanin, Alexandr A, Chernykh, Elena R, Kolchanov, Nikolay A, Bogachev, Sergey S

“…Vitamin D transporter (DBP) is a multifunctional protein. Site-specific deglycosylation results in its conversion to group-specific component protein-derived…”
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Oncolytic Effect of Adenoviruses Serotypes 5 and 6 Against U87 Glioblastoma Cancer Stem Cells by ROMANENKO, MARGARITA V., DOLGOVA, EVGENIYA V., OSIPOV, IVAN D., RITTER, GENRIKH S., SIZOVA, MARIYA S., PROSKURINA, ANASTASIA S., EFREMOV, YAROSLAV R., BAYBORODIN, SERGEY I., POTTER, EKATERINA A., TARANOV, OLEG S., OMIGOV, VLADIMIR V., KOCHNEVA, GALINA V., GRAZHDANTSEVA, ANTONINA A., ZAVYALOV, EVGENIY L., RAZUMOV, IVAN A., NETESOV, SERGEY V., BOGACHEV, SERGEY S.

“…Background/Aim: Oncolytic adenoviruses are promising therapeutic agents against both the bulk of tumor cells and cancer stem cells. The present study intended…”
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The new general biological property of stem-like tumor cells Part I. Peculiarities of the process of the double-stranded DNA fragments internalization into stem-like tumor cells by Ritter, Genrikh S, Dolgova, Evgeniya V, Petrova, Daria D, Efremov, Yaroslav R, Proskurina, Anastasia S, Potter, Ekaterina A, Ruzanova, Vera S, Kirikovich, Svetlana S, Levites, Evgeniy V, Taranov, Oleg S, Ostanin, Alexandr A, Chernykh, Elena R, Kolchanov, Nikolay A, Bogachev, Sergey S

“…Stem-like tumor cells of ascites carcinoma Krebs-2 and Epstein-Barr virus-induced B-lymphoma were shown to possess the innate capability of binding and…”
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Cancer Stem Cells: Emergent Nature of Tumor Emergency by Efremov, Yaroslav R, Proskurina, Anastasia S, Potter, Ekaterina A, Dolgova, Evgenia V, Efremova, Oksana V, Taranov, Oleg S, Ostanin, Aleksandr A, Chernykh, Elena R, Kolchanov, Nikolay A, Bogachev, Sergey S

“…A functional analysis of 167 genes overexpressed in Krebs-2 tumor initiating cells was performed. In the first part of the study, the genes were analyzed for…”
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Efficacy of the new therapeutic approach in curing malignant neoplasms on the model of human glioblastoma by Dolgova, Evgeniya V, Andrushkevich, Oleg M, Kisaretova, Polina E, Proskurina, Anastasia S, Ritter, Genrikh S, Dubatolova, Tatyana D, Romanenko, Margarita V, Taranov, Oleg S, Efremov, Yaroslav R, Zavyalov, Evgeniy L, Romaschenko, Alexandr V, Mishinov, Sergey V, Kirikovich, Svetlana S, Levites, Evgeniy V, Potter, Ekaterina A, Ostanin, Alexandr A, Chernykh, Elena R, Roshchin, Stanislav Yu, Bervitskiy, Anatoliy V, Moysak, Galina I, Rzaev, Jamil A, Bogachev, Sergey S

“…Glioma is a highly invasive tumor, frequently disposed in essential areas of the brain, which makes its surgical excision extremely difficult; meanwhile…”
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Identification of the xenograft and its ascendant sphere-forming cell line as belonging to EBV-induced lymphoma, and characterization of the status of sphere-forming cells by Dolgova, Evgeniya V, Petrova, Daria D, Proskurina, Anastasia S, Ritter, Genrikh S, Kisaretova, Polina E, Potter, Ekaterina A, Efremov, Yaroslav R, Bayborodin, Sergey I, Karamysheva, Tatiana V, Romanenko, Margarita V, Netesov, Sergey V, Taranov, Oleg S, Ostanin, Aleksandr A, Chernykh, Elena R, Bogachev, Sergey S

“…We have characterized the human cell line arised from the Epstein-Barr virus (EBV) positive multiple myeloma aspirate subjected to the long-term cultivation…”
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Experimental Comparison of the In Vivo Efficacy of Two Novel Anticancer Therapies by RUZANOVA, VERA S., PROSKURINA, ANASTASIA S., RITTER, GENRIKH S., EFREMOV, YAROSLAV R., NIKOLIN, VALERIY P., POPOVA, NELLY A., NAPRIMEROV, VASILIY A., DOLGOVA, EVGENIA V., POTTER, EKATERINA A., KIRIKOVICH, SVETLANA S., LEVITES, EVGENIY V., MUSTAFIN, ZAKHAR S., LASHIN, SERGEY A., BURAKOVA, EKATERINA A., STETSENKO, DMITRY A., OSTANIN, ALEXANDR A., CHERNYKH, ELENA R., BOGACHEV, SERGEY S.

“…Background/Aim: We compared the therapeutic efficacy of two recently developed experimental anticancer technologies: 1) in situ vaccination based on local…”
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Characterization of biological peculiarities of the radioprotective activity of double-stranded RNA isolated from Saccharomyces сerevisiae by Ritter, Genrikh S., Nikolin, Valeriy P., Popova, Nelly A., Proskurina, Anastasia S., Kisaretova, Polina E., Taranov, Oleg S., Dubatolova, Tatiana D., Dolgova, Evgenia V., Potter, Ekaterina A., Kirikovich, Svetlana S., Efremov, Yaroslav R., Bayborodin, Sergey I., Romanenko, Margarita V., Meschaninova, Maria I., Venyaminova, Aliya G., Kolchanov, Nikolay A., Shurdov, Mikhail A., Bogachev, Sergey S.

“…Protection from ionizing radiation is the most important component in the curing malignant neoplasms, servicing atomic reactors, and resolving the situations…”
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Approbation of the Cancer Treatment Approach Based on the Eradication of TAMRA+ Cancer Stem Cells in a Model of Murine Cyclophosphamide Resistant Lymphosarcoma by Kisaretova, Polina E, Kirikovich, Svetlana S, Ritter, Genrich S, Efremov, Yaroslav R, Taranov, Oleg S, Dubatolova, Tatyana D, Proskurina, Anastasia S, Potter, Ekaterina A, Dolgova, Evgenia V, Sidorov, Sergey V, Ostanin, Aleksandr A, Chernykh, Elena R, Bogachev, Sergey S

“…We previously have described the "3+1" tumors cure approach consisting of individual time schedule of cyclophosphamide and dsDNA preparation administrations…”
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Theoretical premises of a "three in one" therapeutic approach to treat immunogenic and nonimmunogenic cancers: a narrative review by Proskurina, Anastasia S, Ruzanova, Vera S, Ostanin, Alexandr A, Chernykh, Elena R, Bogachev, Sergey S

“…We describe experimental and theoretical premises of a powerful cancer therapy based on the combination of three approaches. These include (I) vaccination…”
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Efficacy of a new cancer treatment strategy based on eradication of tumor-initiating stem cells in a mouse model of Krebs-2 solid adenocarcinoma by Potter, Ekaterina A, Proskurina, Anastasia S, Ritter, Genrikh S, Dolgova, Evgenia V, Nikolin, Valeriy P, Popova, Nelly A, Taranov, Oleg S, Efremov, Yaroslav R, Bayborodin, Sergey I, Ostanin, Aleksandr A, Chernykh, Elena R, Kolchanov, Nikolay A, Bogachev, Sergey S

“…Krebs-2 solid carcinoma was cured using a new "3+1" strategy for eradication of Krebs-2 tumor-initiating stem cells. This strategy was based on synchronization…”
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Identification of cancer stem cells and a strategy for their elimination by Dolgova, Evgenia V, Alyamkina, Ekaterina A, Efremov, Yaroslav R, Nikolin, Valeriy P, Popova, Nelly A, Tyrinova, Tamara V, Kozel, Artem V, Minkevich, Alexandra M, Andrushkevich, Oleg M, Zavyalov, Evgeniy L, Romaschenko, Alexander V, Bayborodin, Sergey I, Taranov, Oleg S, Omigov, Vladimir V, Shevela, Ekaterina Ya, Stupak, Vyacheslav V, Mishinov, Sergey V, Rogachev, Vladimir A, Proskurina, Anastasia S, Mayorov, Vladimir I, Shurdov, Mikhail A, Ostanin, Alexander A, Chernykh, Elena R, Bogachev, Sergey S

“…It has been established previously that up to 40% of mouse CD34 + hematopoietic stem cells are capable of internalizing exogenous dsDNA fragments both in vivo…”
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Antitumor efficacy of multi-target in situ vaccinations with CpG oligodeoxynucleotides, anti-OX40, anti-PD1 antibodies, and aptamers by Proskurina, Anastasia S, Ruzanova, Vera S, Ritter, Genrikh S, Efremov, Yaroslav R, Mustafin, Zakhar S, Lashin, Sergey A, Burakova, Ekaterina A, Fokina, Alesya A, Zatsepin, Timofei S, Stetsenko, Dmitry A, Leplina, Olga Y, Ostanin, Alexandr A, Chernykh, Elena R, Bogachev, Sergey S

“…To overcome immune tolerance to cancer, the immune system needs to be exposed to a multi-target action intervention. Here, we investigated the activating…”
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Delivery and processing of exogenous double-stranded DNA in mouse CD34+ hematopoietic progenitor cells and their cell cycle changes upon combined treatment with cyclophosphamide and double-stranded DNA by Dolgova, Evgenia V., Efremov, Yaroslav R., Orishchenko, Konstantin E., Andrushkevich, Oleg M., Alyamkina, Ekaterina A., Proskurina, Anastasia S., Bayborodin, Sergey I., Nikolin, Valeriy P., Popova, Nelly A., Chernykh, Elena R., Ostanin, Alexandr A., Taranov, Oleg S., Omigov, Vladimir V., Minkevich, Alexandra M., Rogachev, Vladimir A., Bogachev, Sergey S., Shurdov, Mikhail A.

“…We previously reported that fragments of exogenous double-stranded DNA can be internalized by mouse bone marrow cells without any transfection. Our present…”
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Novel Cancer Stem Marker and Its Applicability for Grading Primary Human Gliomas by Dolgova, Evgeniya V., Mishinov, Sergey V., Proskurina, Anastasiya S., Potter, Ekaterina A., Efremov, Yaroslav R., Bayborodin, Sergey I., Tyrinova, Tamara V., Stupak, Vyacheslav V., Ostatin, Alexandr A., Chernykh, Elena R., Bogachev, Sergey S.

“…Poorly differentiated cell populations including tumor-initiating stem cells have been demonstrated to display a unique ability to natively internalize…”
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