Search Results - "Boga, Ibrahim"

The impact of rare and low-frequency genetic variants in common variable immunodeficiency (CVID) by Bisgin, Atil, Sonmezler, Ozge, Boga, Ibrahim, Yilmaz, Mustafa

“…Next Generation Sequencing (NGS) has uncovered hundreds of common and rare genetic variants involved in complex and rare diseases including immune deficiencies…”
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Analysis of ACE2 and TMPRSS2 coding variants as a risk factor for SARS‐CoV‐2 from 946 whole‐exome sequencing data in the Turkish population by Duman, Nilgun, Tuncel, Gulten, Bisgin, Atil, Bozdogan, Sevcan Tug, Sag, Sebnem Ozemri, Gul, Seref, Kiraz, Aslihan, Balta, Burhan, Erdogan, Murat, Uyanik, Bulent, Canbek, Sezin, Ata, Pinar, Geckinli, Bilgen Bilge, Arslan Ates, Esra, Alavanda, Ceren, Yesim Ozdemir, Sevda, Sezer, Ozlem, Ozgon, Gulay Oner, Gurkan, Hakan, Guler, Kubra, Boga, Ibrahim, Kaya, Niyazi, Alemdar, Adem, Sayan, Murat, Dundar, Munis, Ergoren, Mahmut Cerkez, Temel, Sehime Gulsun

“…Heterogeneity in symptoms associated with COVID‐19 in infected patients remains unclear. ACE2 and TMPRSS2 gene variants are considered possible risk factors…”
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Identification of a novel homozygous variant in the alkaline phosphate (ALPL) gene associated with hypophosphatasia by Bisgin, Atil, Boga, Ibrahim, Cetin, Cihan, Buyukkurt, Selim

“…The lack of awareness of patient risk factors, failure to obtain adequate family history, was discussed by clinical experience in prenatal testing of…”
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Germline landscape of BRCAs by 7-site collaborations as a BRCA consortium in Turkey by Bisgin, Atil, Sag, Sebnem Ozemri, Dogan, Muhammet E., Yildirim, Mahmut S., Gumus, Aydeniz Aydin, Akkus, Nejmiye, Balasar, Ozgur, Durmaz, Ceren D., Eroz, Recep, Altiner, Sule, Alemdar, Adem, Aliyeva, Lamia, Boga, Ibrahim, Cam, Fethi S., Dogan, Berkcan, Esbah, Onur, Hanta, Abdullah, Mujde, Cem, Ornek, Cemre, Ozer, Sinem, Rencuzogullari, Cagla, Sonmezler, Ozge, Bozdogan, Sevcan Tug, Dundar, Munis, Temel, Sehime G.

“…BRCA1/2 mutations play a significant role in cancer pathogenesis and predisposition particularly in breast, ovarian and prostate cancers. Thus, germline…”
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A Multicenter Study of Genotype Variation/Demographic Patterns in 2475 Individuals Including 1444 Cases With Breast Cancer in Turkey by Boga, Ibrahim, Ozemri Sag, Sebnem, Duman, Nilgun, Ozdemir, Sevda Yesim, Ergoren, Mahmut Cerkez, Dalci, Kubilay, Mujde, Cem, Parsak, Cem Kaan, Rencuzogullari, Cagla, Sonmezler, Ozge, Yalav, Orcun, Alemdar, Adem, Aliyeva, Lamiya, Bozkurt, Ozlem, Cetintas, Sibel, Cubukcu, Erdem, Deligonul, Adem, Dogan, Berkcan, Ornek Erguzeloglu, Cemre, Evrensel, Turkkan, Gokgoz, Sehsuvar, Senol, Kazim, Tolunay, Sahsine, Akyurek, Esra, Basgoz, Neslihan, Gökçe, Nuriye, Dundar, Bilge, Ozturk, Figen, Taskin, Duygu, Demirtas, Mercan, Cag, Murat, Diker, Omer, Olgun, Polat, Tug Bozdogan, Sevcan, Dundar, Munis, Bisgin, Atil, Temel, Sehime Gulsun

“…Breast cancer (BC) is the most common cancer type in women and may be inherited, mostly in an autosomal dominant pattern. The clinical diagnosis of BC relies…”
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Abstract 4264: Liquid biopsy and FFPE tissue based somatic BRCA1/2 variant screening in breast and ovarian cancer by Boga, Ibrahim, Sonmezler, Ozge, Bisgin, Atil

“…Abstract Next generation sequencing (NGS) has widened its use since it provides highly precise and accurate genetic testing with reasonable costs in tumor…”
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Treatment, classification, and review of Tapia syndrome by Boğa, Ibrahim, Aktas, Sarper

“…Tapia syndrome was first described by Antonio Garcia Tapia in 1904. Then, he believed that the existing lesion, resulting in some neurologic symptoms, was…”
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Abstract 3602: Validation and implementation of next-generation sequencing in liquid biopsies by a novel NGS platform: Focus on non-small cell lung cancer by Bisgin, Atil, Sonmezler, Ozge, Boga, Ibrahim

“…Abstract Introduction: Liquid biopsy as a novel and non-invasive test for the surveillance of cancer is rapidly growing, by next-generation sequencing (NGS)…”
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Diagnostic utility of next generation sequencing for somatic variants in cancer: A seven year cumulative cohort by Boga, Ibrahim, Sonmezler, Ozge, Rencuzogullari, Cagla, Mujde, Cem, Tug Bozdogan, Sevcan, Bisgin, Atil

“…e15060 Background: Next generation sequencing (NGS) makes it possible to identify the specific molecular biomarkers to define patient eligibility for targeted…”
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Abstract 3346: Changes of gut microbiota in FAP and UC that might harbor colorectal cancer carcinogenesis by Bisgin, Atil, Hanta, Abdullah, Rencuzogullari, Ahmet, Boga, Ibrahim

“…Abstract Inflammatory bowel diseases, Familial adenomatous polyposis(FAP) and colorectal cancer(CRC) are associated with alterations of the intestinal…”
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Short Lasting Pediatric Laparoscopic Surgery: Are Muscle Relaxants Necessary? Endotracheal Intubation vs Laryngeal Mask Airway by Tulgar, Serkan, Boga, Ibrahim, Cakiroglu, Basri, Thomas, David Terence

“…Abstract Purpose Technical advances have led to lower insufflation pressures and shorter anesthesia times for children undergoing laparoscopic procedures In…”
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Integration of Liquid Biopsies into Clinical Laboratory Applications via NGS in Cancer Diagnostics by Sonmezler, Ozge, Boga, Ibrahim, Bisgin, Atil

“…Next Generation Sequencing is one of the latest advances in molecular testing and clinical laboratory applications. Next Generation Sequencing techniques…”
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Percutaneous internal ring suturing is a safe and effective method for the minimal invasive treatment of pediatric inguinal hernia: Experience with 250 cases by Thomas, David Terence, Göcmen, Kamil Basar, Tulgar, Serkan, Boga, Ibrahim

“…Abstract Background/Purpose Percutaneous internal ring suturing (PIRS) is a minimally invasive method for repair of pediatric inguinal hernia. In this study we…”
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Abstract 1972: The significance of liquid biopsy in colorectal cancer via GeneReader NGS Systems by Mujde, Cem, Hanta, Abdullah, Sonmezler, Ozge, Rencuzogullari, Ahmet, Boga, Ibrahim, Bisgin, Atil

“…Abstract Background: In terms of precision medicine, not only tumoral tissue samples but also with liquid biopsy for somatic variants detection, have been used…”
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The Utility of Next-Generation Sequencing for Primary Immunodeficiency Disorders: Experience from a Clinical Diagnostic Laboratory by Bingol, Gulbin, Yilmaz, Mustafa, Boga, Ibrahim, Yalcin, Arzu D., Altıntaş, Derya Ufuk

“…Introduction. Primary immune deficiency disorders (PIDs) are a group of diseases with profound defects in immune cells. The traditional diagnostics have…”
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Meta-analysis and single-center experience on the comprehensive genomic characterization and landscape of BRCA1 and BRCA2 in Turkey by Bisgin, Atil, Boga, Ibrahim, Sonmezler, Ozge, Mujde, Cem, Hanta, Abdullah, Tug Bozdogan, Sevcan

“…Abstract only e13611 Background: The detection of BRCA1 and BRCA2 mutations both somatic and germ-line became essential for the clinical management strategies…”
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Clinical assessment of HRD scoring in relation to PARPi response in terms of statistical guidance on reporting results for CDx tests evaluation by Bisgin, Atil, Boga, Ibrahim, Eskut, Kaan Ihsan, Rencuzogullari, Cagla, Sonmezler, Ozge, Kose, Fatih, Besen, Ali Ayberk, Olmez, Omer Fatih, Disel, Umut, Kocer, Nazım Emrah, Bolat, Filiz, Jinga, Dan-Corneliu, Lazar, Ioana, Pathak, Surajit

“…e17597 Background: Homologous recombination deficiency (HRD) is a tumor characteristic that can be assessed via different biomarkers such as individual…”
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BRCA mutation characteristics in a series of index cases of breast cancer selected independent of family history by Bisgin, Atil, Boga, Ibrahim, Yalav, Orcun, Sonmezler, Ozge, Tug Bozdogan, Sevcan

“…Certain genetic predisposition factors, such as BRCA1 and BRCA2 mutations play a pivotal role in familial breast cancer development in both males and females…”
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An Updated Review on Recent Advances in the Usage of Novel Therapeutic Peptides for Breast Cancer Treatment by Das, Alakesh, Adhikari, Suman, Deka, Dikshita, Bisgin, Atil, Paul, Sujay, Balidya, Nabajyoti, Boga, Ibrahim, Banerjee, Antara, Pathak, Surajit

“…Breast cancer is among the most frequently occurring cancer for women globally. Conventional therapies for breast cancer are found to be expensive and cause…”
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A Rare Pathological Phenotype of Endometrioid Serous and Clear-Cell Ovarian Cancer with PIK3CA Mutations in Relation to The Excellent Response of Alpelisib by Bayram, Ertugrul, Khatib, Ghanim, Guney, Burak, Kilicbagir, Emine, Gulec, Huru Rabia, Boga, Ibrahim, Paydas, Semra

“…Patients with metastatic ovarian cancer who develop resistance to standard therapy with or without platinum need to search for other therapeutic choices…”
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