Search Results - "Boffa, Lidia C."

Effects in live cells of a c- myc anti-gene PNA linked to a nuclear localization signal by Boffa, Lidia C, Cutrona, Giovanna, Carpaneto, Elisabetta M, Ulivi, Massimo, Roncella, Silvio, Landt, Olfert, Ferrarini, Manlio

“…Peptide nucleic acids (PNA) are synthetic homologs of nucleic acids in which the phosphate-sugar polynucleotide backbone is replaced by a flexible polyamide…”
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Inhibition of the translocated c-myc in Burkitt's Lymphoma by a PNA complementary to the Eμ enhancer by CUTRONA, Giovanna, CARPANETO, Elisabetta M, PONZANELLI, Anna, ULIVI, Massimo, MILLO, Enrico, SCARFI, Sonia, RONCELLA, Silvio, BENATTI, Umberto, BOFFA, Lidia C, FERRARINI, Manlio

“…In Burkitt's Lymphoma there is an up-regulation of the c-myc oncogene caused by its translocation from chromosome 8 to chromosome 14, often close to the E mu…”
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Dihydrotestosterone as a selective cellular/nuclear localization vector for anti-gene peptide nucleic acid in prostatic carcinoma cells by BOFFA, L. C, SCARFI, S, MARIANI, M. R, DAMONTE, G, ALLFREY, V. G, BENATTI, U, MORRIS, P. L

“…Peptide nucleic acids (PNAs) are synthetic structural analogues of DNA and RNA that, if allowed to enter the cell, bind to the complementary polynucleotide…”
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Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers by Alagón, Alejandro, Stock, Roberto P, Olvera, Alejandro, Sánchez, Ricardo, Saralegui, Andrés, Scarfì, Sonia, Sanchez-Lopez, Rosana, Ramos, Marco A, Boffa, Lidia C, Benatti, Umberto

“…Peptide nucleic acids (PNAs) may be a potent tool for gene function studies in medically important parasitic organisms, especially those that have not before…”
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Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats by BOFFA, L. C, LUPTON, J. R, MARIANI, M. R, CEPPI, M, NEWMARK, H. L, SCALMATI, A, LIPKIN, M

“…The effect of increasing amounts of wheat bran (0, 5, 10, 20%) in AIN-76 semisynthetic diet on colonic luminal short chain fatty acids, epithelial cell histone…”
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Correlation between butyrate-induced histone hyperacetylation turn-over and c-myc expression by Mariani, Maria Rita, Carpaneto, Elisabetta M., Ulivi, Massimo, Allfrey, Vincent G., Boffa, Lidia C.

“…Transcriptionally active chromatin has an high level of histone acetylation, a post-transcriptional modification known to alter nucleosomal conformation…”
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Invasion of the CAG Triplet Repeats by a Complementary Peptide Nucleic Acid Inhibits Transcription of the Androgen Receptor and TATA-binding Protein Genes and Correlates with Refolding of an Active Nucleosome Containing a Unique AR Gene Sequence by Boffa, L C, Morris, P L, Carpaneto, E M, Louissaint, M, Allfrey, V G

“…The DNA sequence of the genes for the androgen receptor (AR) and TATA-binding protein (TBP), like many other genes encoding transcription factors, contains a…”
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Isolation of Active Genes Containing CAG Repeats by DNA Strand Invasion by a Peptide Nucleic Acid by Boffa, Lidia C., Carpaneto, Elisabetta M., Allfrey, Vincent G.

“…An amplification of tandem CAG trinucleotide sequences in DNA due to errors in DNA replication is involved in at least four hereditary neurodegenerative…”
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Inhibition of Neomycin Phosphorotransferase Expression in Entamoeba histolytica with Antisense Peptide Nucleic Acid (PNA) Oligomers by Stock, Roberto P, Olvera, Alejandro, ı̀, Sonia Scarf, Sánchez, Ricardo, Ramos, Marco A, Boffa, Lidia C, Benatti, Umberto, Landt, Olfert, Alagón, Alejandro

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Therapeutically promising PNA complementary to a regulatory sequence for c-myc: pharmacokinetics in an animal model of human Burkitt's lymphoma by Boffa, Lidia C, Cutrona, Giovanna, Cilli, Michele, Mariani, Maria Rita, Matis, Serena, Pastorino, Martina, Damonte, Gianluca, Millo, Enrico, Roncella, Silvio, Ferrarini, Manlio

“…In Burkitt's lymphoma (BL) cells c-myc is often translocated in proximity to the Emu enhancer of the Ig gene locus. This translocation causes c-myc…”
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Aberrant and nonrandom methylation of chromosomal DNA-binding proteins of colonic epithelial cells by 1,2-dimethylhydrazine by Boffa, L C, Gruss, R J, Allfrey, V G

“…The alkylating carcinogen 1,2-dimethylhydrazine (DMH) induces colonic tumors with high incidence. The sites of in vivo modification of target macromolecules…”
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Activation of sodium cyanate for selective inhibition of protein synthesis in cultured tumor cells by Boffa, L C, Kozak, S, Allfrey, V G

“…Sodium cyanate, a selective inhibitor of protein synthesis in animal tumors in situ, has no comparable effect when added to tumor cells in culture. However, a…”
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Differences in colonic nuclear proteins of two mouse strains with different susceptibilities to 1, 2-dimethylhydrazine-induced carcinogenesis by Boffa, L C, Diwan, B A, Gruss, R, Allfrey, V G

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Characteristic complements of nuclear nonhistone proteins in colonic epithelial tumors by Boffa, L C, Allfrey, V G

“…Nuclei were isolated from colonic epithelial tumors induced in rats by the administration of 1,2-dimethylhydrazine. The nuclei were fractionated according to…”
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Properties of an Acidic Histone-binding Protein Fraction from Cell Nuclei by Vidali, Giorgio, Boffa, Lidia C., Allfrey, Vincent G.

“…Calf thymus nuclei contain a histone-binding protein which specifically deacetylates histone Fractions F2A1 and F3 by a hydrolytic cleavage of ε-N-acetyllysyl…”
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Changes in Nuclear Acidic Protein Complement of Red Blood Cells during Embryonic Development by Vidali, G, Boffa, L C, Littau, V C, Allfrey, K M, Allfrey, V G

“…The complement of nuclear acidic proteins has been compared in erythroid cells of the duck embryo at different stages of development and in adult erythrocytes…”
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Selective hypermethylation of transcribed nucleosomal DNA by sodium butyrate by Boffa, L C, Mariani, M R, Parker, M I

“…Previous studies have shown that treatment of cultured fibroblasts with millimolar concentrations of sodium butyrate results in increased methylation of…”
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Contrasting effects of PNA invasion of the chimeric DMMYC gene on transcription of its myc and PVT domains by Boffa, L C, Carpaneto, E M, Mariani, M R, Louissaint, M, Allfrey, V G

“…A peptide nucleic acid (PNA) complementary to a unique DNA sequence in the second exon of the human myc proto-oncogene was tested for its effects on…”
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Recovery of transcriptionally active chromatin restriction fragments by binding to organomercurial-agarose magnetic beads. A rapid and sensitive method for monitoring changes in higher order chromatin structure during gene activation and repression by CHEN-CLELAND, T. A, BOFFA, L. C, CARPANETO, E. M, MARIANI, M. R, VALENTIN, E, MENDEZ, E, ALLFREY, V. G

“…The unfolding of nucleosomes along transcriptionally active DNA sequences uncovers previously shielded cysteinyl-thiol groups of histone H3 molecules located…”
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Selective release of chromosomal proteins during limited DNAase 1 digestion of avian erythrocyte chromatin by Vidali, G, Boffa, L C, Allfrey, V G

“…Duck erythrocyte chromatin has been treated with DNAase 1 under conditions that are known to digest selectively the structural genes coding for globin mRNAs…”
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