Search Results - "Boezen, Marike H."
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A systematic review and narrative synthesis of data-driven studies in schizophrenia symptoms and cognitive deficits
Published in Translational psychiatry (21-07-2020)“…To tackle the phenotypic heterogeneity of schizophrenia, data-driven methods are often applied to identify subtypes of its symptoms and cognitive deficits…”
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2
Lifetime Smoking History and Cause-Specific Mortality in a Cohort Study with 43 Years of Follow-Up
Published in PloS one (07-04-2016)“…In general, smoking increases the risk of mortality. However, it is less clear how the relative risk varies by cause of death. The exact impact of changes in…”
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3
From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function
Published in Respiratory research (03-11-2018)“…Genetic and environmental factors play a role in the development of COPD. The epigenome, and more specifically DNA methylation, is recognized as important link…”
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4
A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma
Published in PLoS genetics (08-03-2017)“…IL-33 is a tissue-derived cytokine that induces and amplifies eosinophilic inflammation and has emerged as a promising new drug target for asthma and allergic…”
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5
Gender differences in asthma development and remission during transition through puberty: The TRacking Adolescents' Individual Lives Survey (TRAILS) study
Published in Journal of allergy and clinical immunology (01-09-2010)“…Background During puberty, a gender shift in asthma prevalence occurs, with a preponderance of boys before puberty. The mechanisms underlying this gender shift…”
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Influence of perinatal distress on adverse birth outcomes: A prospective study in the Tigray region, northern Ethiopia
Published in PloS one (13-07-2023)“…In low-income countries, where socioeconomic adversities and perinatal distress are common, adverse birth outcomes are significant public health problems. In…”
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Ambient air pollution, lung function, and airway responsiveness in asthmatic children
Published in Journal of allergy and clinical immunology (01-02-2016)“…Background Although ambient air pollution has been linked to reduced lung function in healthy children, longitudinal analyses of pollution effects in asthmatic…”
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Meta-analyses on Suspected Chronic Obstructive Pulmonary Disease Genes: A Summary of 20 Years' Research
Published in American journal of respiratory and critical care medicine (01-10-2009)“…Chronic obstructive pulmonary disease (COPD) is a complex disorder with high mortality worldwide. Studies on the role of candidate genes and their…”
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9
Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction
Published in Atherosclerosis (01-06-2013)“…Abstract Arterial calcification is a well-known risk factor for coronary artery disease (CAD) and myocardial infarction (MI). We performed a genome-wide…”
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10
E-waste environmental contamination and harm to public health in China
Published in Frontiers of medicine (01-06-2015)“…The adverse effects of electronic waste (e-waste) on the human body have stirred up concern in recent years. China is one of the countries that confront…”
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11
Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations
Published in Human molecular genetics (15-05-2018)“…Abstract Causal genes of chronic obstructive pulmonary disease (COPD) remain elusive. The current study aims at integrating genome-wide association studies…”
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12
Early and late onset pre-eclampsia and small for gestational age risk in subsequent pregnancies
Published in PloS one (27-03-2020)“…Pre-eclampsia shares pathophysiology with intrauterine growth restriction. To investigate whether delivery of a small for gestational age (SGA) infant in the…”
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13
Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts
Published in Thorax (01-11-2017)“…COPD is a heterogeneous disease, but there is little consensus on specific definitions for COPD subtypes. Unsupervised clustering offers the promise of…”
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14
Asthma and Chronic Obstructive Pulmonary Disease: Common Genes, Common Environments?
Published in American journal of respiratory and critical care medicine (15-06-2011)“…Asthma and chronic obstructive pulmonary disease (COPD) show similarities and substantial differences. The Dutch hypothesis stipulated that asthma and COPD…”
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15
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis
Published in Respiratory research (02-04-2019)“…A growing number of studies clearly demonstrate a substantial association between chronic obstructive pulmonary disease (COPD) and cardiovascular diseases…”
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16
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Published in Nature genetics (01-03-2009)“…Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of inflammatory responses and thus have important roles in the…”
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17
Physical and Psychosocial Factors Associated With Physical Activity in Patients With Chronic Obstructive Pulmonary Disease
Published in Archives of physical medicine and rehabilitation (01-12-2013)“…Abstract Objectives To assess physical activity and sitting time in patients with chronic obstructive pulmonary disease (COPD) and to investigate which…”
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18
BMI and lifetime changes in BMI and cancer mortality risk
Published in PloS one (16-04-2015)“…Body Mass Index (BMI) is known to be associated with cancer mortality, but little is known about the link between lifetime changes in BMI and cancer mortality…”
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19
Epigenome-wide association study of lung function level and its change
Published in The European respiratory journal (01-07-2019)“…Previous reports link differential DNA methylation (DNAme) to environmental exposures that are associated with lung function. Direct evidence on lung function…”
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20
Psychosocial work factors and blood pressure among 63 800 employees from The Netherlands in the Lifelines Cohort Study
Published in Journal of epidemiology and community health (1979) (01-01-2022)“…Previous studies on the association between psychosocial work factors and blood pressure mainly focused on specific occupations or populations and had limited…”
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