Search Results - "Boezen, H. M."

Severe exacerbations predict excess lung function decline in asthma by Bai, T. R, Vonk, J. M, Postma, D. S, Boezen, H. M

“…Severe asthma exacerbations are periods of intense airway inflammation that have been hypothesised to contribute to structural changes in the airways. If so,…”
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Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor by Hiltermann, T.J.N., Pore, M.M., van den Berg, A., Timens, W., Boezen, H.M., Liesker, J.J.W., Schouwink, J.H., Wijnands, W.J.A., Kerner, G.S.M.A., Kruyt, F.A.E., Tissing, H., Tibbe, A.G.J., Terstappen, L.W.M.M., Groen, H.J.M.

“…Initial response of small-cell lung cancer (SCLC) to chemotherapy is high, and recurrences occur frequently, leading to early death. This study investigated…”
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Increased risk of fundic gland polyps during long‐term proton pump inhibitor therapy by JALVING, M., KOORNSTRA, J. J., WESSELING, J., BOEZEN, H. M., DE JONG, S., KLEIBEUKER, J. H.

“…Summary Background It is controversial whether proton pump inhibitor use leads to fundic gland polyp development. Aim To determine whether fundic gland polyp…”
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Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium by Vonk, J M, Scholtens, S, Postma, D S, Moffatt, M F, Jarvis, D, Ramasamy, A, Wjst, M, Omenaas, E R, Bouzigon, E, Demenais, F, Nadif, R, Siroux, V, Polonikov, A V, Solodilova, M, Ivanov, V P, Curjuric, I, Imboden, M, Kumar, A, Probst-Hensch, N, Ogorodova, L M, Puzyrev, V P, Bragina, E Yu, Freidin, M B, Nolte, I M, Farrall, A M, Cookson, W O C M, Strachan, D P, Koppelman, G H, Boezen, H M

“…Genome-wide association studies have identified novel genetic associations for asthma, but without taking into account the role of active tobacco smoking. This…”
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Pesticides and other occupational exposures are associated with airway obstruction: the LifeLines cohort study by de Jong, K, Boezen, H M, Kromhout, H, Vermeulen, R, Postma, D S, Vonk, J M

“…Objectives Occupational exposures are important and possibly modifiable contributors to the global burden of chronic obstructive pulmonary disease (COPD)…”
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Early development of the metabolic syndrome after chemotherapy for testicular cancer by de Haas, E.C., Altena, R., Boezen, H.M., Zwart, N., Smit, A.J., Bakker, S.J.L., van Roon, A.M., Postma, A., Wolffenbuttel, B.H.R., Hoekstra, H.J., van Leeuwen, F.E., Sleijfer, D.T., Gietema, J.A.

“…The metabolic syndrome (MS) might increase the risk of cardiovascular disease in testicular cancer (TC) survivors. We investigated its prevalence, development,…”
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Anti-inflammatory effects of inhaled carbon monoxide in patients with COPD: a pilot study by Bathoorn, E, Slebos, D-J, Postma, D. S, Koeter, G. H, van Oosterhout, A. J. M, van der Toorn, M, Boezen, H. M, Kerstjens, H. A. M

“…In vitro and in vivo studies have shown that carbon monoxide (CO) has both anti-inflammatory and anti-oxidant capacities. Since chronic obstructive pulmonary…”
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Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity by Gooden, M J M, Wiersma, V R, Boerma, A, Leffers, N, Boezen, H M, ten Hoor, K A, Hollema, H, Walenkamp, A M E, Daemen, T, Nijman, H W, Bremer, E

“…Background: In certain cancers, expression of CXCL16 and its receptor CXCR6 associate with lymphocyte infiltration, possibly aiding anti-tumour immune…”
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Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma by Jongepier, H., Boezen, H. M., Dijkstra, A., Howard, T. D., Vonk, J. M., Koppelman, G. H., Zheng, S. L., Meyers, D. A., Bleecker, E. R., Postma, D. S.

“…Summary Background Asthma is a genetically complex disease characterized by respiratory symptoms, intermittent airway obstruction and airway…”
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Respiratory Health in Prematurely Born Preschool Children with and without Bronchopulmonary Dysplasia by Vrijlandt, E.J.L.E., MD, PhD, Boezen, H.M., PhD, Gerritsen, J., MD, PhD, Stremmelaar, E.F., MD, Duiverman, E.J., MD, PhD

“…Objective To investigate the respiratory health of preterm infants with bronchopulmonary dysplasia (BPD) at preschool age and to determine whether lung…”
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E-cadherin gene polymorphisms in asthma patients using inhaled corticosteroids by LERODIAKONOU, D, POSTMA, D. S, KOPPELMAN, G. H, BOEZEN, H. M, GERRITSEN, J, TEN HACKEN, N, TIMENS, W, VONK, J. M

“…E-cadherins form intercellular junctions that maintain epithelial integrity. Epithelial integrity is impaired in asthma and can be restored by inhaled…”
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Dietary factors and lung function in the general population: wine and resveratrol intake by SIEDLINSKI, M, BOER, J. M. A, SMIT, H. A, POSTMA, D. S, BOEZEN, H. M

“…Wine intake is associated with a better lung function in the general population, yet the source of this effect is unknown. Resveratrol, a polyphenol in wine,…”
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Longitudinal changes in cardiac function after cisplatin-based chemotherapy for testicular cancer by Altena, R., Hummel, Y.M., Nuver, J., Smit, A.J., Lefrandt, J.D., de Boer, R.A., Voors, A.A., van den Berg, M.P., de Vries, E.G.E., Boezen, H.M., Gietema, J.A.

“…Cross-sectional studies showed that treatment with cisplatin chemotherapy for testicular cancer is associated with an increased incidence of cardiac…”
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Preventive Intervention Possibilities in Radiotherapy- and Chemotherapy-induced Oral Mucositis: Results of Meta-analyses by Stokman, M.A., Spijkervet, F.K.L., Boezen, H.M., Schouten, J.P., Roodenburg, J.L.N., de Vries, E.G.E.

“…The aim of these meta-analyses was to evaluate the effectiveness of interventions for the prevention of oral mucositis in cancer patients treated with head and…”
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Childhood factors associated with asthma remission after 30 year follow up by Vonk, J M, Postma, D S, Boezen, H M, Grol, M H, Schouten, J P, Koëter, G H, Gerritsen, J

“…Background: Factors contributing to either “complete” or “clinical” remission of asthma are important to know since there is no cure for the disease. Methods:…”
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Identification of genes and pathways associated with cytotoxic T lymphocyte infiltration of serous ovarian cancer by Leffers, N, Fehrmann, R S N, Gooden, M J M, Schulze, U R J, ten Hoor, K A, Hollema, H, Boezen, H M, Daemen, T, de Jong, S, Nijman, H W, van der Zee, A G J

“…Background: Tumour-infiltrating lymphocytes (TILs) are predictors of disease-specific survival (DSS) in ovarian cancer. It is largely unknown what factors…”
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Treatment of Breast Cancer Cells by IGF1R Tyrosine Kinase Inhibitor Combined with Conventional Systemic Drugs by HARTOG, H, VAN DER GRAAF, W. T. A, BOEZEN, H. M, WESSELING, J

“…Insulin-like growth factor-1 receptor (IGF1R) is a tyrosine kinase receptor mediating cell growth and survival of cancer cells. We studied responses to IGF1R…”
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A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants by Nedeljkovic, Ivana, Terzikhan, Natalie, Vonk, Judith M, van der Plaat, Diana A, Lahousse, Lies, van Diemen, Cleo C, Hobbs, Brian D, Qiao, Dandi, Cho, Michael H, Brusselle, Guy G, Postma, Dirkje S, Boezen, H M, van Duijn, Cornelia M, Amin, Najaf

“…Chronic obstructive pulmonary disease (COPD) is a complex and heritable disease, associated with multiple genetic variants. Specific familial types of COPD may…”
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Polymorphisms in the TLR6 gene associated with the inverse association between childhood acute lymphoblastic leukemia and atopic disease by Miedema, K G E, Tissing, W J E, te Poele, E M, Kamps, W A, Alizadeh, B Z, Kerkhof, M, de Jongste, J C, Smit, H A, de Pagter, A P, Bierings, M, Boezen, H M, Postma, D S, de Bont, E S J M, Koppelman, G H

“…Little is known about the etiology of childhood acute lymphoblastic leukemia (ALL). The presence of atopic disease has been shown to protect against developing…”
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SERPINE1 -675 4G/5G polymorphism is associated with asthma severity and inhaled corticosteroid response by DIJKSTRA, A, POSTMA, D. S, BRUINENBERG, M, VAN DIEMEN, C. C, BOEZEN, H. M, KOPPELMAN, G. H, TIMENS, W, VONK, J. M

“…Asthma is characterised by chronic airway inflammation and remodelling, which can be (partially) suppressed by inhaled corticosteroids (ICSs). Plasminogen…”
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