Search Results - "Boettzauw, Trine"

ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signaling Network Activating Myeloid Zinc Finger-1-Dependent Cathepsin B Expression by Rafn, Bo, Nielsen, Christian Friberg, Andersen, Sofie Hagel, Szyniarowski, Piotr, Corcelle-Termeau, Elisabeth, Valo, Erkka, Fehrenbacher, Nicole, Olsen, Charlotta Johanne, Daugaard, Mads, Egebjerg, Christina, Bøttzauw, Trine, Kohonen, Pekka, Nylandsted, Jesper, Hautaniemi, Sampsa, Moreira, José, Jäättelä, Marja, Kallunki, Tuula

“…Aberrant ErbB2 receptor tyrosine kinase activation in breast cancer is strongly linked to an invasive disease. The molecular basis of ErbB2-driven invasion is…”
Get full text

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration by Johansen, Lars Dan, Naumanen, Tiina, Knudsen, Astrid, Westerlund, Nina, Gromova, Irina, Junttila, Melissa, Nielsen, Christina, Bøttzauw, Trine, Tolkovsky, Aviva, Westermarck, Jukka, Coffey, Eleanor T, Jäättelä, Marja, Kallunki, Tuula

“…Loss-of-function mutations in the IKBKAP gene, which encodes IKAP (ELP1), cause familial dysautonomia (FD), with defective neuronal development and…”
Get full text

c-Jun NH sub(2)-Terminal Kinase 2 Is Required for Ras Transformation Independently of Activator Protein 1 by Nielsen, Christina, Thastrup, Jacob, Boettzauw, Trine, Jaeaettelae, Marja, Kallunki, Tuula

“…Active Ras oncogene is expressed in similar to 30% of human cancers. Yet, very little is known about the molecular mechanisms responsible for its transforming…”
Get full text

ErbB2 signaling pathways in the regulation of cathepsin activity by Kallunki, Tuula, Rafn, Bo, Szyniatowski, Piotr, Fehrenbacher, Nicole, Boettzauw, Trine, Nielsen, Christina, Nylandsted, Jesper, Jaeaettelae, Marja

“…Amplification and overexpression of ErbB2 oncogene confers approximately 25-30% of human cancer. It leads to activation of several cellular signaling pathways,…”
Get full text