Search Results - "Boerries, M."

TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC by Gladilin, E., Ohse, S., Boerries, M., Busch, H., Xu, C., Schneider, M., Meister, M., Eils, R.

“…Importance of growth factor (GF) signaling in cancer progression is widely acknowledged. Transforming growth factor beta (TGFβ) is known to play a key role in…”
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The German Network for Personalized Medicine to enhance patient care and translational research by Illert, A. L., Stenzinger, A., Bitzer, M., Horak, P., Gaidzik, V. I., Möller, Y., Beha, J., Öner, Ö., Schmitt, F., Laßmann, S., Ossowski, S., Schaaf, C. P., Hallek, M., Brümmendorf, T. H., Albers, P., Fehm, T., Brossart, P., Glimm, H., Schadendorf, D., Bleckmann, A., Brandts, C. H., Esposito, I., Mack, E., Peters, C., Bokemeyer, C., Fröhling, S., Kindler, T., Algül, H., Heinemann, V., Döhner, H., Bargou, R., Ellenrieder, V., Hillemanns, P., Lordick, F., Hochhaus, A., Beckmann, M. W., Pukrop, T., Trepel, M., Sundmacher, L., Wesselmann, S., Nettekoven, G., Kohlhuber, F., Heinze, O., Budczies, J., Werner, M., Nikolaou, K., Beer, A. J., Tabatabai, G., Weichert, W., Keilholz, U., Boerries, M., Kohlbacher, O., Duyster, J., Thimme, R., Seufferlein, T., Schirmacher, P., Malek, N. P.

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Perioperative cell-free mutant KRAS dynamics in patients with pancreatic cancer by Hipp, J, Hussung, S, Timme-Bronsert, S, Boerries, M, Biesel, E, Fichtner-Feigl, S, Fritsch, R, Wittel, U A

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STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett’s adenocarcinomas by Timme, S, Ihde, S, Fichter, C D, Waehle, V, Bogatyreva, L, Atanasov, K, Kohler, I, Schöpflin, A, Geddert, H, Faller, G, Klimstra, D, Tang, L, Reinheckel, T, Hauschke, D, Busch, H, Boerries, M, Werner, M, Lassmann, S

“…Signal transducer and activator of transcription 3 (STAT3) is altered in several epithelial cancers and represents a potential therapeutic target. Here, STAT3…”
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Conformation-specific antibodies reveal distinct actin structures in the nucleus and the cytoplasm by Schoenenberger, C.-A., Buchmeier, S., Boerries, M., Sütterlin, R., Aebi, U., Jockusch, B.M.

“…For many years the existence of actin in the nucleus has been doubted because of the lack of phalloidin staining as well as the failure to document nuclear…”
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Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response by Dvornikov, D., Schneider, M. A., Ohse, S., Szczygieł, M., Titkova, I., Rosenblatt, M., Muley, T., Warth, A., Herth, F. J., Dienemann, H., Thomas, M., Timmer, J., Schilling, M., Busch, H., Boerries, M., Meister, M., Klingmüller, U.

“…In lung cancer a deregulation of Transforming Growth Factor-β (TGFβ) signaling has been observed. Yet, the impact of TGFβ in squamous cell carcinoma of the…”
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Biomarker detection in pancreatic ductal adenocarcinoma by Klett, H, Klose, M, Kowar, S, Bronsert, P, Küsters, S, Werner, M, Christoph, P, Busch, H, Boerries, M

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S230: HUMAN ΒETA‐DEFENSIN 2 TREATMENT MODULATES THE INTESTINAL MICROBIOME AND THE ALLOGENEIC T CELL RESPONSE TO LIMIT ACUTE GRAFT‐VERSUS‐HOST DISEASE by Rückert, T., Andrieux, G., Boerries, M., Woessner, N. M., Minguet, S., Doetsch, S., Aumann, K., Schiff, M, Braun, L. M., Haring, E., Siranosian, B. A., Bhatt, A. S., Nordkild, P., Wehkamp, J., Jensen, B. A. H., Duyster, J., Zeiser, R., Köhler, N.

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IDENTIFICATION AND CHARACTERISATION OF THE LYMPHOMA‐INITIATING CELL (LIC) POPULATION IN AN ALCL MOUSE MODEL by Illert, A.L., Kreutmair, S., Klingeberg, C., Andrieux, G., Miething, C., Follo, M., Pfeifer, D., Boerries, M., Duyster, J.

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1936P Targeted therapy of desmoplastic small round cell tumor guided by multilayered molecular profiling by Renner, M., Oleś, M., Paramasivam, N., Schneider, A., Heilig, C.E., Modugno, C., Herremans, C., Mock, A., Lipka, D., Bauer, S., Kindler, T., Brandts, C.H., Keilholz, U., Boerries, M., Kuster, B., Hübschmann, D., Schlesner, M., Glimm, H., Schlenk, R.F., Fröhling, S.

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872 Epithelial integrin α3 impacts the composition of the cellular microenvironment by He, Y., Thriene, K., Boerries, M., Busch, H., Dengjel, J., Has, C.

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Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers by Jahn, A., Rump, A., Widmann, T.J., Heining, C., Horak, P., Hutter, B., Paramasivam, N., Uhrig, S., Gieldon, L., Drukewitz, S., Kübler, A., Bermudez, M., Hackmann, K., Porrmann, J., Wagner, J., Arlt, M., Franke, M., Fischer, J., Kowalzyk, Z., William, D., Weth, V., Oster, S., Fröhlich, M., Hüllein, J., Valle González, C., Kreutzfeldt, S., Mock, A., Heilig, C.E., Lipka, D.B., Möhrmann, L., Hanf, D., Oleś, M., Teleanu, V., Allgäuer, M., Ruhnke, L., Kutz, O., Knurr, A., Laßmann, A., Endris, V., Neumann, O., Penzel, R., Beck, K., Richter, D., Winter, U., Wolf, S., Pfütze, K., Geörg, C., Meißburger, B., Buchhalter, I., Augustin, M., Aulitzky, W.E., Hohenberger, P., Kroiss, M., Schirmacher, P., Schlenk, R.F., Keilholz, U., Klauschen, F., Folprecht, G., Bauer, S., Siveke, J.T., Brandts, C.H., Kindler, T., Boerries, M., Illert, A.L., von Bubnoff, N., Jost, P.J., Metzeler, K.H., Bitzer, M., Schulze-Osthoff, K., von Kalle, C., Brors, B., Stenzinger, A., Weichert, W., Hübschmann, D., Fröhling, S., Glimm, H., Schröck, E., Klink, B.

“…Germline variant evaluation in precision oncology opens new paths toward the identification of patients with genetic tumor risk syndromes and the exploration…”
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O26 - Topic: AS04-MDS Biology and Pathogenesis/AS04c-MDS Mouse models (GEMMS, PDX): LEUKEMOGENESIS IN GATA2 HAPLOINSUFFICIENT MICE IS A SECONDARY EVENT AFTER BONE MARROW FAILURE by Fernandez-Orth, J., Weiss, J., Geoffroy, A., Gonzalez-Mendez, I., Steinemann, D., Quintanilla-Martinez, L., Boerries, M., Niemeyer, C., Erlacher, M.

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Topic: AS04-MDS Biology and Pathogenesis/AS04c-MDS Mouse models (GEMMS, PDX) by Fernandez-Orth, J., Weiss, J., Geoffroy, A., Gonzalez-Mendez, I., Steinemann, D., Quintanilla-Martinez, L., Boerries, M., Niemeyer, C., Erlacher, M.

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302 Molecular and mutational signatures of squamous cell carcinomas in epidermolysis bullosa by Lu, S., Hess, M.E., Reimer, A., Castiglia, D., He, Y., Rafei-Shamsabadi, D.A., Bubnoff, Dv, Meiss, F., Boerries, M., Has, C.

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181 Loss of integrin α3 impacts keratinocyte microenvironment by He, Y., Thriene, K., Boerries, M., Busch, H., Dengjel, J., Has, C.

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780 - Biomarker detection in pancreatic ductal adenocarcinoma by Klett, H., Klose, M., Kowar, S., Bronsert, P., Küsters, S., Werner, M., Christoph, P., Busch, H., Boerries, M.

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Epithelioid hemangioendotheliomas of the liver and lung in children and adolescents by Hettmer, Simone, Andrieux, Geoffroy, Hochrein, Jochen, Kurz, Philipp, Rössler, Jochen, Lassmann, Silke, Werner, Martin, Bubnoff, Nikolas, Peters, Christoph, Koscielniak, Ewa, Sparber‐Sauer, Monika, Niemeyer, Charlotte, Mentzel, Thomas, Busch, Hauke, Boerries, Melanie

“…Epithelioid hemangioendothelioma (EHE) is a rare, vascular sarcoma. Visceral forms arise in the liver/ lungs. We review the clinical and molecular phenotype of…”
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Molekulare Tumorboards: Molekularbasierte Therapieempfehlung in der klinischen Versorgung by Jung, J., Gräßel, L., Boerries, M., Illert, A. L.

“…Zusammenfassung Molekulare Tumorboards (MTBs) haben sich in den letzten Jahren an universitären Spitzenzentren und Krebszentren etabliert und zu einem…”
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Cardiac adenoviral S100A1 gene delivery rescues failing myocardium by Most, Patrick, Pleger, Sven T., Völkers, Mirko, Heidt, Beatrix, Boerries, Melanie, Weichenhan, Dieter, Löffler, Eva, Janssen, Paul M.L., Eckhart, Andrea D., Martini, Jeffrey, Williams, Matthew L., Katus, Hugo A., Remppis, Andrew, Koch, Walter J.

“…Cardiac-restricted overexpression of the Ca 2+ -binding protein S100A1 has been shown to lead to increased myocardial contractile performance in vitro and in…”
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