Search Results - "Boerno, Stefan T"

An Unbiased Molecular Approach Using 3′-UTRs Resolves the Avian Family-Level Tree of Life by Kuhl, Heiner, Frankl-Vilches, Carolina, Bakker, Antje, Mayr, Gerald, Nikolaus, Gerhard, Boerno, Stefan T, Klages, Sven, Timmermann, Bernd, Gahr, Manfred

“…Abstract Presumably, due to a rapid early diversification, major parts of the higher-level phylogeny of birds are still resolved controversially in different…”
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Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency by Adachi, Kenjiro, Kopp, Wolfgang, Wu, Guangming, Heising, Sandra, Greber, Boris, Stehling, Martin, Araúzo-Bravo, Marcos J., Boerno, Stefan T., Timmermann, Bernd, Vingron, Martin, Schöler, Hans R.

“…Transcription factor (TF)-mediated reprogramming to pluripotency is a slow and inefficient process, because most pluripotency TFs fail to access relevant…”
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Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis by Timmermann, Bernd, Kerick, Martin, Roehr, Christina, Fischer, Axel, Isau, Melanie, Boerno, Stefan T, Wunderlich, Andrea, Barmeyer, Christian, Seemann, Petra, Koenig, Jana, Lappe, Michael, Kuss, Andreas W, Garshasbi, Masoud, Bertram, Lars, Trappe, Kathrin, Werber, Martin, Herrmann, Bernhard G, Zatloukal, Kurt, Lehrach, Hans, Schweiger, Michal R

“…Colorectal cancer (CRC) is with approximately 1 million cases the third most common cancer worldwide. Extensive research is ongoing to decipher the underlying…”
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Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics by Haupt, Armin, Joberty, Gerard, Bantscheff, Marcus, Fröhlich, Holger, Stehr, Henning, Schweiger, Michal R, Fischer, Axel, Kerick, Martin, Boerno, Stefan T, Dahl, Andreas, Lappe, Michael, Lehrach, Hans, Gonzalez, Cayetano, Drewes, Gerard, Lange, Bodo Mh

“…The heat shock protein 90 (Hsp90) is required for the stability of many signalling kinases. As a target for cancer therapy it allows the simultaneous…”
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Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency by Adachi, Kenjiro, Kopp, Wolfgang, Wu, Guangming, Heising, Sandra, Greber, Boris, Stehling, Martin, Araúzo-Bravo, Marcos J., Boerno, Stefan T., Timmermann, Bernd, Vingron, Martin, Schöler, Hans R.

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Next-generation sequencing technologies for DNA methylation analyses in cancer genomics by Boerno, Stefan T, Grimm, Christina, Lehrach, Hans, Schweiger, Michal-Ruth

“…For the first time, the development of next-generation sequencing technologies has brought about tools to investigate epigenetic alterations in an unbiased,…”
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Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development by Vallecillo-García, Pedro, Orgeur, Mickael, vom Hofe-Schneider, Sophie, Stumm, Jürgen, Kappert, Verena, Ibrahim, Daniel M., Börno, Stefan T., Hayashi, Shinichiro, Relaix, Frédéric, Hildebrandt, Katrin, Sengle, Gerhard, Koch, Manuel, Timmermann, Bernd, Marazzi, Giovanna, Sassoon, David A., Duprez, Delphine, Stricker, Sigmar

“…Fibro-adipogenic progenitors (FAPs) are an interstitial cell population in adult skeletal muscle that support muscle regeneration. During development,…”
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miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer by Pasqualini, Lorenza, Bu, Huajie, Puhr, Martin, Narisu, Narisu, Rainer, Johannes, Schlick, Bettina, Schäfer, Georg, Angelova, Mihaela, Trajanoski, Zlatko, Börno, Stefan T, Schweiger, Michal R, Fuchsberger, Christian, Klocker, Helmut

“…The normal prostate as well as early stages and advanced prostate cancer (PCa) require a functional androgen receptor (AR) for growth and survival. The recent…”
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Genome-wide strategies identify downstream target genes of chick connective tissue-associated transcription factors by Orgeur, Mickael, Martens, Marvin, Leonte, Georgeta, Nassari, Sonya, Bonnin, Marie-Ange, Börno, Stefan T, Timmermann, Bernd, Hecht, Jochen, Duprez, Delphine, Stricker, Sigmar

“…Connective tissues support organs and play crucial roles in development, homeostasis and fibrosis, yet our understanding of their formation is still limited…”
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Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation by Börno, Stefan T, Fischer, Axel, Kerick, Martin, Fälth, Maria, Laible, Mark, Brase, Jan C, Kuner, Ruprecht, Dahl, Andreas, Grimm, Christina, Sayanjali, Behnam, Isau, Melanie, Röhr, Christina, Wunderlich, Andrea, Timmermann, Bernd, Claus, Rainer, Plass, Christoph, Graefen, Markus, Simon, Ronald, Demichelis, Francesca, Rubin, Mark A, Sauter, Guido, Schlomm, Thorsten, Sültmann, Holger, Lehrach, Hans, Schweiger, Michal R

“…Prostate cancer is the second most common cancer among men worldwide. Alterations in the DNA methylation pattern can be one of the leading causes for prostate…”
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High-throughput miRNA and mRNA sequencing of paired colorectal normal, tumor and metastasis tissues and bioinformatic modeling of miRNA-1 therapeutic applications by Röhr, Christina, Kerick, Martin, Fischer, Axel, Kühn, Alexander, Kashofer, Karl, Timmermann, Bernd, Daskalaki, Andriani, Meinel, Thomas, Drichel, Dmitriy, Börno, Stefan T, Nowka, Anja, Krobitsch, Sylvia, McHardy, Alice C, Kratsch, Christina, Becker, Tim, Wunderlich, Andrea, Barmeyer, Christian, Viertler, Christian, Zatloukal, Kurt, Wierling, Christoph, Lehrach, Hans, Schweiger, Michal R

“…MiRNAs are discussed as diagnostic and therapeutic molecules. However, effective miRNA drug treatments with miRNAs are, so far, hampered by the complexity of…”
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ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer by Kacprzyk, Lukasz A, Laible, Mark, Andrasiuk, Tatjana, Brase, Jan C, Börno, Stefan T, Fälth, Maria, Kuner, Ruprecht, Lehrach, Hans, Schweiger, Michal R, Sültmann, Holger

“…Overexpression of ERG transcription factor due to genomic ERG-rearrangements defines a separate molecular subtype of prostate tumors. One of the consequences…”
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A dual transcript-discovery approach to improve the delimitation of gene features from RNA-seq data in the chicken model by Orgeur, Mickael, Martens, Marvin, Börno, Stefan T, Timmermann, Bernd, Duprez, Delphine, Stricker, Sigmar

“…The sequence of the chicken genome, like several other draft genome sequences, is presently not fully covered. Gaps, contigs assigned with low confidence and…”
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