Search Results - "Boerner, Susann"

Infrared Microspectroscopy Detects Protein Misfolding Cyclic Amplification (PMCA)-induced Conformational Alterations in Hamster Scrapie Progeny Seeds by Daus, Martin L., Wagenführ, Katja, Thomzig, Achim, Boerner, Susann, Hermann, Peter, Hermelink, Antje, Beekes, Michael, Lasch, Peter

“…The self-replicative conformation of misfolded prion proteins (PrP) is considered a major determinant for the seeding activity, infectiousness, and strain…”
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Quantitative detection and biological propagation of scrapie seeding activity in vitro facilitate use of prions as model pathogens for disinfection by Pritzkow, Sandra, Wagenführ, Katja, Daus, Martin L, Boerner, Susann, Lemmer, Karin, Thomzig, Achim, Mielke, Martin, Beekes, Michael

“…Prions are pathogens with an unusually high tolerance to inactivation and constitute a complex challenge to the re-processing of surgical instruments. On the…”
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Towards further reduction and replacement of animal bioassays in prion research by cell and protein misfolding cyclic amplification assays by Boerner, Susann, Wagenführ, Katja, Daus, Martin L, Thomzig, Achim, Beekes, Michael

“…Laboratory animals have long since been used extensively in bioassays for prions in order to quantify, usually in terms of median infective doses [ID50], how…”
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