Search Results - "Boerner, Renee"

SH2- and SH3-mediated Interactions between Focal Adhesion Kinase and Src by Thomas, Jeffrey W., Ellis, Byron, Boerner, Renee J., Knight, Wilson B., White, Gilbert C., Schaller, Michael D.

“…Intramolecular SH2 and SH3 interactions mediate enzymatic repression of the Src kinases. One mechanism of activation is disruption of these interactions by the…”
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Evidence from directed mutagenesis that aspartate 170 of the D1 polypeptide influences the assembly and/or stability of the manganese cluster in the photosynthetic water-splitting complex by Boerner, Renee J, Nguyen, Anh P, Barry, Bridgette A, Debus, Richard J

“…To identify amino acid residues that influence the assembly or stability of the manganese cluster in photosystem II, we have generated site-directed mutations…”
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EPR characterization of an oxygen-evolving photosystem II preparation from the transformable cyanobacterium Synechocystis 6803 by Noren, George H, Boerner, Renee J, Barry, Bridgette A

“…The transformable cyanobacterium Synechocystis 6803 has a photosynthetic apparatus that is similar to that of plants. Because of the ease with which this…”
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Comparison of Cytochrome b-559 Content in Photosystem II Complexes from Spinach and Synechocystis Species PCC 6803 by MacDonald, Gina M, Boerner, Renee J, Everly, R. Michael, Cramer, William A, Debus, Richard J, Barry, Bridgette A

“…Cytochrome b-559 is an integral component of photosystem II complexes from both plants and cyanobacteria. However, the number of cytochrome b-559 associated…”
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Kinetic mechanisms of the forward and reverse pp60c-src tyrosine kinase reactions by Boerner, Renee J, Barker, Sean C, Knight, Wilson B

“…The kinetic mechanism of the pp60c-src tyrosine kinase (src TK) reaction was investigated in the forward and reverse directions. In the forward direction,…”
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Examination of the Dephosphorylation Reactions Catalyzed by pp60c-src Tyrosine Kinase Explores the Roles of Autophosphorylation and SH2 Ligand Binding by Boerner, Renee J, Kassel, Daniel B, Edison, Ann M, Knight, Wilson B

“…pp60c-src tyrosine kinase (srcTK) catalyzes the dephosphorylation of phosphotyrosine-containing peptides, including phosphopeptides that bind with high…”
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Correlation of the Phosphorylation States of pp60c- src with Tyrosine Kinase Activity:  The Intramolecular pY530−SH2 Complex Retains Significant Activity If Y419 Is Phosphorylated by Boerner, Renee J, Kassel, Daniel B, Barker, Sean C, Ellis, Byron, DeLacy, Pam, Knight, Wilson B

“…Rapid digestion of pp60c- src tyrosine kinase (src TK) in combination with electrospray ionization mass spectrometry enabled the determination of the time…”
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Catalytic Activity of the SH2 Domain of Human pp60c-src; Evidence from NMR, Mass Spectrometry, Site-Directed Mutagenesis and Kinetic Studies for an Inherent Phosphatase Activity by Boerner, Renee J, Consler, Thomas G, Gampe, Robert T, Weigl, Debbra, Willard, Derril H, Davis, Donald G, Edison, Ann M, Loganzo, Frank, Kassel, D. B

“…During solution structural studies it was apparent that the human recombinant pp60c-src SH2 domain (srcSH2, residues 144-249) possessed an inherent phosphatase…”
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The catalytic base of enolase is a sulfhydryl group by Weiss, Paul M, Boerner, Renee J, Cleland, W. W

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Enzymic synthesis and inhibitory characteristics of tartronate semialdehyde phosphate by Weiss, Paul M, Boerner, Renee J, Cleland, W. W

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Identifying and modulating disulfide formation in the biopharmaceutical production of a recombinant protein vaccine candidate by Bouvier, Anne, Chapline, Jaymi, Boerner, Renee, Jeyarajah, Shanthini, Cook, Susan, Acharya, Prathima S, Henderson, Ian, Schrimsher, Jeffrey L, Shepard, Scot R

“…Structural conversion of the serotype A recombinant botulinum neurotoxin heavy chain fragment (rBoNTA(H c)) produced intracellularly in Pichia pastoris yeast…”
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Large-Scale Purification of Recombinant Human Angiostatin by Shepard, Scot R., Boucher, Robert, Johnston, Jeremy, Boerner, Renee, Koch, George, Madsen, John W., Grella, Davida, Sim, B.Kim Lee, Schrimsher, Jeffrey L.

“…A process for the purification of recombinant human angiostatin (rhAngiostatin), produced by Pichia pastoris fermentation operated at the 2000-L scale, is…”
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Isotopic labeling and EPR spectroscopy show that a tyrosine residue is the terminal electron donor, Z, in manganese-depleted photosystem II preparations by Boerner, R J, Barry, B A

“…Photosystem II contains two redox active species, D and Z, which in the oxidized and paramagnetic form give rise to similar EPR signals. Both signals are…”
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Correlation of the Phosphorylation States of pp60 c- src with Tyrosine Kinase Activity:  The Intramolecular pY530−SH2 Complex Retains Significant Activity If Y419 Is Phosphorylated by Boerner, Renee J., Kassel, Daniel B., Barker, Sean C., Ellis, Byron, DeLacy, Pam, Knight, Wilson B.

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EPR evidence that the M+ radical, which is observed in three site-directed mutants of photosystem II, is a tyrosine radical by BOERNER, R. J, BARRY, B. A

“…Isotopic labeling of Synechocystis sp. PCC 6803 and EPR spectroscopy have been used to demonstrate that photosystem II contains two redox active tyrosines, D…”
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Removal of stable tyrosine radical D+ affects the structure or redox properties of tyrosine Z in manganese-depleted photosystem II particles from Synechocystis 6803 by BOERNER, R. J, BIXBY, K. A, NGUYEN, A. P, NOREN, G. H, DEBUS, R. J, BARRY, B. A

“…Photosystem II contains two redox-active tyrosines, D and Z. To understand the function of the dark stable tyrosine radical, D+, we have characterized two…”
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Biochemical and spectroscopic studies of the photosynthetic water-splitting complex by Boerner, Renee Joyce

“…This thesis project examined photosystem II donor side redox components and their function in oxygenic photosynthesis. Biochemical and spectroscopic techniques…”
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Enzymatic synthesis and inhibitory characteristics of tartronate semialdehyde phosphate by Weiss, P M, Boerner, R J, Cleland, W W

“…The immediate product of the pyruvate kinase catalyzed phosphorylation of beta-hydroxypyruvate is the enol of tartronate semialdehyde phosphate (TSP). The…”
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