Search Results - "Boerner, A"

Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer by EDER, Joseph Paul, VANDE WOUDE, George F, BOERNER, Scott A, LO RUSSO, Patricia M

“…A wide variety of human malignancies exhibit sustained c-Met stimulation, overexpression, or mutation, including carcinomas of the breast, liver, lung, ovary,…”
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A Phase I Study of Foretinib, a Multi-Targeted Inhibitor of c-Met and Vascular Endothelial Growth Factor Receptor 2 by EDER, Joseph Paul, SHAPIRO, Geoffrey I, MCCALLUM, Stewart, HEATH, Elisabeth I, BOERNER, Scott A, LORUSSO, Patricia M, APPLEMAN, Leonard J, ZHU, Andrew X, MILES, Dale, KEER, Harold, CANCILLA, Belinda, CHU, Felix, HITCHCOCK-BRYAN, Suzanne, SHERMAN, Laurie

“…Foretinib is an oral multikinase inhibitor targeting Met, RON, Axl, and vascular endothelial growth factor receptor. We conducted a phase I,…”
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Genetic mapping within the wheat D genome reveals QTL for germination, seed vigour and longevity, and early seedling growth by Landjeva, S, Lohwasser, U, Börner, A

“…Quantitative trait loci (QTL) controlling germination, seed vigour and longevity, and early seedling growth were identified using a set of common wheat lines…”
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Meta-analysis of the relationship between dose and benefit in phase I targeted agent trials by Gupta, Sachin, Hunsberger, Sally, Boerner, Scott A, Rubinstein, Larry, Royds, Robert, Ivy, Percy, LoRusso, Patricia

“…To date, the primary objective of phase I trials has been to safely select the maximum tolerated dose (MTD) of a drug or drug combination for utilization in…”
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A phase 2 study of vorinostat in locally advanced, recurrent, or metastatic adenoid cystic carcinoma by Goncalves, Priscila H, Heilbrun, Lance K, Barrett, Michael T, Kummar, Shivaani, Hansen, Aaron R, Siu, Lillian L, Piekarz, Richard L, Sukari, Ammar W, Chao, Joseph, Pilat, Mary Jo, Smith, Daryn W, Casetta, Lindsay, Boerner, Scott A, Chen, Alice, Lenkiewicz, Elizabeth, Malasi, Smriti, LoRusso, Patricia M

“…Vorinostat is a histone deacetylase inhibitor (HDACi). Based on a confirmed partial response (PR) in an adenoid cystic carcinoma (ACC) patient treated with…”
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Performance of the new Aptima HCV quant Dx assay in comparison to the Cobas TaqMan HCV2 assay for use with the high pure system in the detection and quantification of HCV RNA in plasma or serum by Schalasta, G, Speicher, A, Boerner, A, Enders, M

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European carbon balance. Part 4: integration of carbon and other trace-gas fluxes by SCHULZE, E.D, CIAIS, P, LUYSSAERT, S, SCHRUMPF, M, JANSSENS, I.A, THIRUCHITTAMPALAM, B, THELOKE, J, SAURAT, M, BRINGEZU, S, LELIEVELD, J, LOHILA, A, REBMANN, C, JUNG, M, BASTVIKEN, D, ABRIL, G, GRASSI, G, LEIP, A, FREIBAUER, A, KUTSCH, W, DON, A, NIESCHULZE, J, BÖRNER, A, GASH, J.H, DOLMAN, A.J

“…Overviewing the European carbon (C), greenhouse gas (GHG), and non-GHG fluxes, gross primary productivity (GPP) is about 9.3 Pg yr⁻¹, and fossil fuel imports…”
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Protein expression of DNA damage repair proteins dictates response to topoisomerase and PARP inhibitors in triple-negative breast cancer by Boerner, Julie L, Nechiporchik, Nicole, Mueller, Kelly L, Polin, Lisa, Heilbrun, Lance, Boerner, Scott A, Zoratti, Gina L, Stark, Karri, LoRusso, Patricia M, Burger, Angelika

“…Patients with metastatic triple-negative breast cancer (TNBC) have a poor prognosis. New approaches for the treatment of TNBC are needed to improve patient…”
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Inter-annual and seasonal variability of radial growth, wood density and carbon isotope ratios in tree rings of beech (Fagus sylvatica) growing in Germany and Italy by SKOMARKOVA, M. V, VAGANOV, E. A, MUND, M, KNOHL, A, LINKE, P, BOERNER, A, SCHULZE, E.-D

“…We investigated the variability of tree-ring width, wood density and ^sup 13^C/^sup 12^C in beech tree rings (Fagus sylvatica L.), and analyzed the influence…”
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Integrin Connections Map: To Infinity and beyond by Martin, Karen H., Slack, Jill K., Boerner, Scott A., Martin, Clifford C., Parsons, J. Thomas

“…Integrins are transmembrane proteins that serve as primary sensors of the extracellular matrix (ECM) environment. In response to interactions with the ECM,…”
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PAK1 Phosphorylation of MEK1 Regulates Fibronectin-Stimulated MAPK Activation by Slack-Davis, Jill K., Eblen, Scott T., Zecevic, Maja, Boerner, Scott A., Tarcsafalvi, Adel, Diaz, H. Bruce, Marshall, Mark S., Weber, Michael J., Parsons, J. Thomas, Catling, Andrew D.

“…Activation of the Ras-MAPK signal transduction pathway is necessary for biological responses both to growth factors and ECM. Here, we provide evidence that…”
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Seed conservation in ex situ genebanks—genetic studies on longevity in barley by Nagel, M, Vogel, H, Landjeva, S, Buck-Sorlin, G, Lohwasser, U, Scholz, U, Börner, A

“…Recognizing the danger due to a permanent risk of loss of the genetic variability of cultivated plants and their wild relatives in response to changing…”
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Stable carbon and nitrogen isotope ratios of Eucalyptus and Acacia species along a seasonal rainfall gradient in Western Australia by Schulze, E. D, Nicolle, D, Boerner, A, Lauerer, M, Aas, G, Schulze, I

“…KEY MESSAGE : Eucalyptus and Acacia species were surprisingly similar with respect to variations in δ ¹³ C, δ ¹⁵ N. Both genera respond with speciation and…”
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The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux by ERLICHMAN, Charles, BOERNER, Scott A, KAUFMANN, Scott H, HALLGREN, Christopher G, SPIEKER, Rebecca, WANG, Xiao-Yang, JAMES, C. David, SCHEFFER, George L, MALIEPAARD, Marc, ROSS, Douglas D, BIBLE, Keith C

“…Because the activities of HER family members are elevated and/or aberrant in a variety of human neoplasms, these cell surface receptors are receiving…”
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Post transplant lymphoproliferative disease in pediatric solid organ transplant patients: A possible role for [18 F]-FDG-PET(/CT) in initial staging and therapy monitoring by von Falck, C, Maecker, B, Schirg, E, Boerner, A.R, Knapp, W.H, Klein, C, Galanski, M

“…Abstract Post transplant lymphoproliferative disease (PTLD) is a severe complication after solid organ or bone marrow transplantation. In pediatric transplant…”
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Mapping genes controlling anthocyanin pigmentation on the glume and pericarp in tetraploid wheat (Triticum durum L.) by Khlestkina, E. K, Röder, M. S, Börner, A

“…A novel gene, designated Pg (purple glume), controlling anthocyanin pigmentation of the glume was identified and mapped in an F₂ population from the durum…”
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Molecular mapping of genomic regions associated with wheat seedling growth under osmotic stress by Landjeva, S.,Leibniz Inst. of Plant Genetics and Crop Research, Gatersleben (Germany), Neumann, K.,Leibniz Inst. of Plant Genetics and Crop Research, Gatersleben (Germany), Lohwasser, U.,Leibniz Inst. of Plant Genetics and Crop Research, Gatersleben (Germany), Boerner, A.,Leibniz Inst. of Plant Genetics and Crop Research, Gatersleben (Germany)

“…A quantitative trait loci (QTL) approach was applied to dissect the genetic control of the common wheat seedling response to osmotic stress. A set of 114…”
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Single nucleotide polymorphisms in rye (Secale cereale L.): discovery, frequency, and applications for genome mapping and diversity studies by Varshney, R. K, Beier, U, Khlestkina, E. K, Kota, R, Korzun, V, Graner, A, Börner, A

“…To elucidate the potential of single nucleotide polymorphism (SNP) markers in rye, a set of 48 barley EST (expressed sequence tag) primer pairs was employed to…”
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Mapping of QTLs affecting copper tolerance and the Cu, Fe, Mn and Zn contents in the shoots of wheat seedlings by Balint, A.F, Roeder, M.S, Hell, R, Galiba, G, Boerner, A

“…Quantitative trait loci (QTLs) for Cu-tolerance were determined in wheat plants grown in control or Cu-treated soil in greenhouse. In addition, loci having an…”
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A Multipeptide Vaccine is Safe and Elicits T-cell Responses in Participants With Advanced Stage Ovarian Cancer by CHIANESE-BULLOCK, Kimberly A, IRVIN, William P, YUAN, Arlene, HOGAN, Kevin T, SLINGLUFF, Craig L, PETRONI, Gina R, MURPHY, Cheryl, SMOLKIN, Mark, OLSON, Walter C, COLEMAN, Elizabeth, BOERNER, Scott A, NAIL, Carmel J, NEESE, Patrice Y

“…Nine participants with epithelial ovarian, fallopian tube, or primary peritoneal carcinoma, who were human leukocyte antigen (HLA)-A1, HLA-A2, or HLA-A3, were…”
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