Search Results - "Boer, Patrícia Aline"
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miRNAs, target genes expression and morphological analysis on the heart in gestational protein-restricted offspring
Published in PloS one (29-04-2019)“…Gestational protein restriction was associated with low birth weight, hypertension and higher prevalence of cardiac disorders in adults. Several mechanisms,…”
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Impact of gestational low-protein intake on embryonic kidney microRNA expression and in nephron progenitor cells of the male fetus
Published in PloS one (05-02-2021)“…Here, we have demonstrated that gestational low-protein (LP) intake offspring present lower birth weight, reduced nephron numbers, renal salt excretion,…”
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3
Fetal Undernutrition Programming, Sympathetic Nerve Activity, and Arterial Hypertension Development
Published in Frontiers in physiology (17-11-2021)“…A wealth of evidence showed that low birth weight is associated with environmental disruption during gestation, triggering embryotic or fetal adaptations and…”
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Gestational and Breastfeeding Low-Protein Intake on Blood Pressure, Kidney Structure, and Renal Function in Male Rat Offspring in Adulthood
Published in Frontiers in physiology (22-04-2021)“…: Our previous studies demonstrated that maternal protein-restricted (low-protein, LP) 16-week-old offspring had pronounced nephron number reduction and…”
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CLK2 in GABAergic neurons is critical in regulating energy balance and anxiety-like behavior in a gender-specific fashion
Published in Frontiers in endocrinology (Lausanne) (10-08-2023)“…IntroductionCdc2-like kinase (CLK2) is a member of CLK kinases expressed in hypothalamic neurons and is activated in response to refeeding, leptin, or insulin…”
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Involvement of renal corpuscle microRNA expression on epithelial-to-mesenchymal transition in maternal low protein diet in adult programmed rats
Published in PloS one (19-08-2013)“…Prior study shows that maternal protein-restricted (LP) 16-wk-old offspring have pronounced reduction of nephron number and arterial hypertension associated…”
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Gestational Low Protein Diet Modulation on miRNA Transcriptome and Its Target During Fetal and Breastfeeding Nephrogenesis
Published in Frontiers in physiology (22-06-2021)“…The kidney ontogenesis is the most structurally affected by gestational protein restriction, reducing 28% of their functional units. The reduced nephron number…”
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Vitamin D deficiency contributes to the diabetic kidney disease progression via increase ZEB1/ZEB2 expressions
Published in Nutrition & diabetes (01-07-2023)“…Background Diabetic kidney disease (DKD) remains one of the main causes of end-stage renal disease (ESRD) and mortality in diabetic patients worldwide. Vitamin…”
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Effect of intracerebroventricular epinephrine microinjection on blood pressure and urinary sodium handling in gestational protein-restricted male adult rat offspring
Published in Biology open (01-04-2019)“…In this study, we hypothesized that blunting of the natriuresis response to intracerebroventricularly (ICV) microinjected adrenergic agonists is involved in…”
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10
Impact of maternal protein restriction on Hypoxia-Inducible Factor (HIF) expression in male fetal kidney development
Published in PloS one (04-05-2023)“…Kidney developmental studies have demonstrated molecular pathway changes that may be related to decreased nephron numbers in the male 17 gestational days…”
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11
Mandible development under gestational protein restriction: cellular and molecular mechanisms
Published in Journal of molecular histology (01-10-2024)“…Insufficient evidence regarding how maternal undernutrition affects craniofacial bone development persists. With its unique focus on the impact of gestational…”
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Hypothalamic SOCS-3 expression and the effect of intracerebroventricular angiotensin II injection on water intake and renal sodium handling in SHR
Published in The journal of physiological sciences (01-11-2010)“…In rats, the acute central dipsogenic and natriuretic action of angiotensin II (AngII) seems to be independent of the hemodynamic effects of the peptide;…”
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13
Nuclear localization of SP, CGRP, and NK1R in a subpopulation of dorsal root ganglia subpopulation cells in rats
Published in Cellular and molecular neurobiology (01-03-2006)“…Signals generated by renal pelvic afferent nerves in response to stimulation are transmitted from peripheral processes of dorsal root ganglia neurons to their…”
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14
Transcriptome and morphological analysis on the heart in gestational protein-restricted aging male rat offspring
Published in Frontiers in cell and developmental biology (24-10-2022)“…Adverse factors that influence embryo/fetal development are correlated with increased risk of cardiovascular disease (CVD), type-2 diabetes, arterial…”
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15
Expression of renin–angiotensin system signalling compounds in maternal protein-restricted rats: effect on renal sodium excretion and blood pressure
Published in Nephrology, dialysis, transplantation (01-02-2010)“…Background. Intrauterine growth restriction due to low maternal dietary protein during pregnancy is associated with retardation of foetal growth, renal…”
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Time-course morphological and functional disorders of the kidney induced by long-term high-fat diet intake in female rats
Published in Nephrology, dialysis, transplantation (01-10-2013)“…Evidence is emerging that highlights the far-reaching consequences of a high-fat diet (HFD) on kidney morphology and function disorders. The present study was…”
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Neuromuscular junctions (NMJs): ultrastructural analysis and nicotinic acetylcholine receptor (nAChR) subunit mRNA expression in offspring subjected to protein restriction throughout pregnancy
Published in International journal of experimental pathology (01-04-2017)“…Summary Protein restriction during gestation can alter the skeletal muscle phenotype of offspring; however, little is known with regard to whether this also…”
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Effect of Angiotensin II and Losartan on the Phagocytic Activity of Peritoneal Macrophages from Balb/C Mice
Published in Memórias do Instituto Oswaldo Cruz (01-03-2004)“…Angiotensin II (AII), a product of rennin-angiotensin system, exerts an important role on the function of immune system cells. In this study, the effect of AII…”
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Early changes of hypothalamic angiotensin II receptors expression in gestational protein-restricted offspring: effect on water intake, blood pressure and renal sodium handling
Published in Journal of the renin-angiotensin-aldosterone system (01-09-2013)“…The current study examines changes in the postnatal hypothalamic angiotensin receptors by maternal protein restriction (LP), and its impact on in uteri…”
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Impact of taurine supplementation on blood pressure in gestational protein-restricted offspring: Effect on the medial solitary tract nucleus cell numbers, angiotensin receptors, and renal sodium handling
Published in Journal of the renin-angiotensin-aldosterone system (01-03-2015)“…Objective: The current study considers changes of the postnatal brainstem cell number and angiotensin receptors by maternal protein restriction (LP) and LP…”
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