Search Results - "Boer, Jennifer C"
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The Key Role of TNF-TNFR2 Interactions in the Modulation of Allergic Inflammation: A Review
Published in Frontiers in immunology (09-11-2018)“…Tumor necrosis factor-alpha (TNF) is a pleiotropic cytokine, which is thought to play a major role in the pathogenesis of inflammatory diseases, including…”
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Comprehensive Structural and Molecular Comparison of Spike Proteins of SARS-CoV-2, SARS-CoV and MERS-CoV, and Their Interactions with ACE2
Published in Cells (Basel, Switzerland) (08-12-2020)“…The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has recently emerged in China and caused a disease called coronavirus disease 2019 (COVID-19)…”
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Anti-Cancer Effects of Carnosine-A Dipeptide Molecule
Published in Molecules (Basel, Switzerland) (16-03-2021)“…Carnosine is a dipeptide molecule (β-alanyl-l-histidine) with anti-inflammatory, antioxidant, anti-glycation, and chelating properties. It is used in exercise…”
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Antioxidant-Based Medicinal Properties of Stingless Bee Products: Recent Progress and Future Directions
Published in Biomolecules (Basel, Switzerland) (18-06-2020)“…Stingless bees are a type of honey producers that commonly live in tropical countries. Their use for honey is being abandoned due to its limited production…”
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A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility
Published in Frontiers in immunology (09-12-2022)“…COVID-19 pandemic has been threatening public health and economic development worldwide for over two years. Compared with the original SARS-CoV-2 strain…”
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Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines
Published in Science advances (01-01-2020)“…To be optimally effective, peptide-based vaccines need to be administered with adjuvants. Many currently available adjuvants are toxic, not biodegradable; they…”
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Therapeutic Cancer Vaccines-T Cell Responses and Epigenetic Modulation
Published in Frontiers in immunology (25-01-2019)“…There is great interest in developing efficient therapeutic cancer vaccines, as this type of therapy allows targeted killing of tumor cells as well as…”
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Synthetic Nanoparticles That Promote Tumor Necrosis Factor Receptor 2 Expressing Regulatory T Cells in the Lung and Resistance to Allergic Airways Inflammation
Published in Frontiers in immunology (22-12-2017)“…Synthetic glycine coated 50 nm polystyrene nanoparticles (NP) (PS50G), unlike ambient NP, do not promote pulmonary inflammation, but instead, render lungs…”
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The Effects of Tamoxifen on Tolerogenic Cells in Cancer
Published in Biology (Basel, Switzerland) (17-08-2022)“…Tamoxifen (TAM) is the most prescribed selective estrogen receptor modulator (SERM) to treat hormone-receptor-positive breast cancer patients and has been used…”
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The Development of Surface-Modified Liposomes as an Intranasal Delivery System for Group A Streptococcus Vaccines
Published in Vaccines (Basel) (30-01-2023)“…Intranasal vaccine administration can overcome the disadvantages of injectable vaccines and present greater efficiency for mass immunization. However, the…”
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Poly(hydrophobic Amino Acids) and Liposomes for Delivery of Vaccine against Group A Streptococcus
Published in Vaccines (Basel) (29-07-2022)“…Adjuvants and delivery systems are essential components of vaccines to increase immunogenicity against target antigens, particularly for peptide epitopes (poor…”
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Amino Acid Functionalized Inorganic Nanoparticles as Cutting-Edge Therapeutic and Diagnostic Agents
Published in Bioconjugate chemistry (21-03-2018)“…The field of medical diagnostics and therapeutics is being revolutionized by nanotechnology, from targeted drug delivery to cancer immunotherapy. Inorganic…”
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CXCR4 inhibition enhances radiosensitivity, while inducing cancer cell mobilization in a prostate cancer mouse model
Published in Clinical & experimental metastasis (01-10-2014)“…Preclinical studies show that stroma affects sensitivity of prostate cancer cells via activation of the CXCR4/CXCL12 pathway. Here we studied the effect of…”
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Drug Discovery in Real Life: An Online Learning Activity for Bioinformatics Students
Published in Journal of chemical education (14-02-2023)“…During COVID-19 lockdowns, online learning activities had to be developed for the Undergraduate and Masters by Coursework Bioinformatics students at RMIT…”
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Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection
Published in Journal of colloid and interface science (01-06-2024)“…[Display omitted] Peptide-based vaccines can trigger highly specific immune responses, although peptides alone are usually unable to confer strong humoral or…”
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Dead in the water – Role of relic DNA and primer choice for targeted sequencing surveys of anaerobic sewage sludge intended for biological monitoring
Published in Water research (Oxford) (01-04-2024)“…•Dead sludge biomass skewed DNA-based functional predictions for anaerobic digestion.•PMA-seq is a promising approach for assessing the active biomass of…”
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Polymeric Nanoparticles as a Self‐Adjuvanting Peptide Vaccine Delivery System: The Role of Shape
Published in Advanced functional materials (01-03-2023)“…Antigens incorporated in subunit vaccines are typically poorly immunogenic, so a strong immunostimulant (adjuvant) and/or delivery system is required to boost…”
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CD4+ Foxp3+ Regulatory T-cells in Modulating Inflammatory Microenvironment in Chronic Rhinosinusitis with Nasal Polyps: Progress and Future Prospect
Published in Cytokine (Philadelphia, Pa.) (01-06-2024)“…•Tregs have a vital role that linked to impairment of immune tolerance in CRSwNP.•TNFR2 is preferentially expressed by Tregs and TNFR2 signaling leads to the…”
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Insights into endotoxin-mediated lung inflammation and future treatment strategies
Published in Expert review of respiratory medicine (02-11-2018)“…Airway inflammatory disorders are prevalent diseases in need of better management and new therapeutics. Immunotherapies offer a solution to the problem of…”
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A Perspective Review on the Role of Nanomedicine in the Modulation of TNF-TNFR2 Axis in Breast Cancer Immunotherapy
Published in Journal of oncology (01-01-2019)“…In the past decade, nanomedicine research has provided us with highly useful agents (nanoparticles) delivering therapeutic drugs to target cancer cells. The…”
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