Search Results - "Boelsterli, U.A"

Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes by Kretz-Rommel, A, Boelsterli, U A

“…In a few patients diclofenac produces mild increases in serum aminotransferase activity and in rare cases may be associated with the occurrence of fulminant…”
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Toxicological screening models: drug-induced oxidative hemolysis by Boelsterli, U A, Shie, K P, Brändle, E, Zbinden, G

“…In an attempt to obtain a simple screening system for the assessment of toxic-hemolytic effects of chemical substances, a battery of hematological tests was…”
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Antioxidant and Cytoprotective Properties ofd-Tagatose in Cultured Murine Hepatocytes by Paterna, J.C., Boess, F., Stäubli, A., Boelsterli, U.A.

“…d-Tagatose is a zero-energy producing ketohexose that is a powerful cytoprotective agent against chemically induced cell injury. To further explore the…”
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CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats by Suter-Eichenberger, R, Boelsterli, U.A, Conscience-Egli, M, Lichtensteiger, W, Schlumpf, M

“…Developmental and adult toxicity of musk xylene was studied in Long Evans (LE) rats fed with chow containing musk xylene (MX) in food pellets in concentrations…”
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CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats by Suter-Eichenberger, R, Boelsterli, U.A, Conscience-Egli, M, Lichtensteiger, W, Schlumpf, M

“…Developmental and adult toxicity of musk xylene was studied in Long Evans (LE) rats fed with chow containing musk xylene (MX) in food pellets in concentrations…”
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Modulation of cocaine metabolism in primary rat hepatocyte cultures: effects on irreversible binding and protein biosynthesis by Bouis, P, Boelsterli, U A

“…To study mechanisms of cocaine-induced hepatotoxicity, short-term-cultured rat hepatocytes were exposed to cocaine or norcocaine at 10(-6) to 10(-4) M…”
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In vitro toxicity assessment of cyclosporin A and its analogs in a primary rat hepatocyte culture model by Boelsterli, U A, Bouis, P, Brouillard, J F, Donatsch, P

“…The cytotoxicity of cyclosporin A (CsA), a widely used immunosuppressant drug, was evaluated in primary cultures of rat hepatocytes. Furthermore, the…”
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Toxicological screening by Zbinden, G, Elsner, J, Boelsterli, U A

“…Well-defined dose- and time-related toxic effects of chemicals can often be detected using simple tests with small numbers of animals. The strategies for the…”
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Epoxide hydrolase activity in small biopsy samples of preneoplastic and neoplastic rat liver by Boelsterli, U A, Romagna, F, Viviani, A, Zbinden, G

“…Epoxide hydrolase (EH) activity was measured in serial fine-needle aspiration biopsy (FNAB) samples of male rats chronically treated with the hepatocarcinogen,…”
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