Search Results - "Boeker, Heinz"
-
1
Ketamine decreases resting state functional network connectivity in healthy subjects: implications for antidepressant drug action
Published in PloS one (24-09-2012)“…Increasing preclinical and clinical evidence underscores the strong and rapid antidepressant properties of the glutamate-modulating NMDA receptor antagonist…”
Get full text
Journal Article -
2
Neuropsychodynamic Approach to Depression: Integrating Resting State Dysfunctions of the Brain and Disturbed Self-Related Processes
Published in Frontiers in human neuroscience (27-06-2018)“…A mechanism-based approach was developed focusing on the psychodynamic, psychological and neuronal mechanisms in healthy and depressed persons. In this…”
Get full text
Journal Article -
3
Increased self-focus in major depressive disorder is related to neural abnormalities in subcortical-cortical midline structures
Published in Human brain mapping (01-08-2009)“…Patients with major depressive disorder (MDD) often show a tendency to strongly introspect and reflect upon their self, which has been described as increased…”
Get full text
Journal Article -
4
Imbalance between Left and Right Dorsolateral Prefrontal Cortex in Major Depression Is Linked to Negative Emotional Judgment: An fMRI Study in Severe Major Depressive Disorder
Published in Biological psychiatry (1969) (15-02-2008)“…Background Although recent neuroimaging and therapeutic transcranial magnetic cortex stimulation (TMS) studies suggest imbalance between left and right…”
Get full text
Journal Article -
5
Predicting non-response to multimodal day clinic treatment in severely impaired depressed patients: a machine learning approach
Published in Scientific reports (31-03-2022)“…A considerable number of depressed patients do not respond to treatment. Accurate prediction of non-response to routine clinical care may help in treatment…”
Get full text
Journal Article -
6
Ketamine administration reduces amygdalo-hippocampal reactivity to emotional stimulation
Published in Human brain mapping (01-05-2016)“…Increased amygdala reactivity might lead to negative bias during emotional processing that can be reversed by antidepressant drug treatment. However, little is…”
Get full text
Journal Article -
7
GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI
Published in Nature neuroscience (01-12-2007)“…The human anterior cingulate cortex (ACC) is part of the default-mode network that shows predominant negative blood oxygen level-dependent (BOLD) responses in…”
Get full text
Journal Article -
8
The awareness of the scared - context dependent influence of oxytocin on brain function
Published in Brain imaging and behavior (01-12-2020)“…Oxytocin is both a hormone and a neurotransmitter and has been originally recognized for its role in childbirth and lactation. Later, it became widely known as…”
Get full text
Journal Article -
9
Reduced negative BOLD responses in the default-mode network and increased self-focus in depression
Published in The world journal of biological psychiatry (01-12-2011)“…Abstract Objectives. Functional imaging studies in major depressive disorder (MDD) indicate abnormal resting state neural activity and negative blood…”
Get full text
Journal Article -
10
Differential Alterations in Resting State Functional Connectivity Associated with Depressive Symptoms and Early Life Adversity
Published in Brain sciences (02-05-2021)“…Depression and early life adversity (ELA) are associated with aberrant resting state functional connectivity (FC) of the default mode (DMN), salience (SN), and…”
Get full text
Journal Article -
11
Segregated neural representation of distinct emotion dimensions in the prefrontal cortex—an fMRI study
Published in NeuroImage (Orlando, Fla.) (01-03-2006)“…Emotions are frequently characterized by distinct dimensions such as valence, intensity, and recognition. However, the exact neural representation of these…”
Get full text
Journal Article -
12
Altered Negative BOLD Responses in the Default-Mode Network during Emotion Processing in Depressed Subjects
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2009)Get full text
Journal Article -
13
Executive dysfunction, self, and ego pathology in schizophrenia: an exploratory study of neuropsychology and personality
Published in Comprehensive psychiatry (2006)“…Schizophrenic patients show a variety of symptoms, including positive and negative symptoms and ego pathology. Their exact underlying neuropsychological…”
Get full text
Journal Article -
14
The Relationship Between Aberrant Neuronal Activation in the Pregenual Anterior Cingulate, Altered Glutamatergic Metabolism, and Anhedonia in Major Depression
Published in Archives of general psychiatry (01-05-2009)“…CONTEXT Major depressive disorder (MDD) is characterized by diverse metabolic and functional abnormalities that occur in, among other regions, the pregenual…”
Get full text
Journal Article -
15
Altered negative BOLD responses in the default-mode network during emotion processing in depressed subjects
Published in Neuropsychopharmacology (New York, N.Y.) (01-03-2009)“…Studies using functional magnetic resonance imaging (fMRI) show predominant negative blood oxygenation level-dependent (BOLD) responses (NBRs) in regions of…”
Get full text
Journal Article -
16
Hair glucocorticoid levels decrease after multimodal inpatient treatment and predict therapy outcome in burnout-related depressive disorders
Published in The world journal of biological psychiatry (13-09-2024)“…Hair cortisol concentration (HCC) indicates chronic stress exposure, which is a risk factor in the pathogenesis of burnout and depression. However, findings on…”
Get full text
Journal Article -
17
Sex differences in depressive symptoms and their networks in a treatment-seeking population – a cross-sectional study
Published in Journal of affective disorders (01-01-2021)“…•We assessed sex differences in symptom profiles in depressed inpatients.•Females showed higher psychological anxiety, somatic anxiety and feelings of…”
Get full text
Journal Article -
18
Effects of ketamine on cognition–emotion interaction in the brain
Published in NeuroImage (Orlando, Fla.) (01-01-2016)“…Cognition–emotion interaction in the brain can be investigated by incorporating stimuli with emotional content into cognitive tasks. Emotional stimuli in the…”
Get full text
Journal Article -
19
Functional connectivity between prefrontal cortex and subgenual cingulate predicts antidepressant effects of ketamine
Published in European neuropsychopharmacology (01-04-2019)“…Converging evidence suggests that a single sub-anesthetic dose of ketamine can produce strong and rapid antidepressant effects in patients that do not respond…”
Get full text
Journal Article -
20
The association of interoceptive awareness and alexithymia with neurotransmitter concentrations in insula and anterior cingulate
Published in Social cognitive and affective neuroscience (01-06-2014)“…Alexithymia and increased interoceptive awareness have been associated with affective disorders as well as with altered insula and anterior cingulate cortex…”
Get full text
Journal Article