Search Results - "Boehmer, Christoph"

Role of SGK1 kinase in regulating glucose transport via glucose transporter GLUT4 by Jeyaraj, Sankarganesh, Boehmer, Christoph, Lang, Florian, Palmada, Monica

“…Insulin stimulates glucose transport into muscle and fat cells by enhancing GLUT4 abundance in the plasma membrane through activation of phosphatidylinositol…”
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Post‐translational regulation of EAAT2 function by co‐expressed ubiquitin ligase Nedd4‐2 is impacted by SGK kinases by Boehmer, Christoph, Palmada, Monica, Rajamanickam, Jeyaganesh, Schniepp, Roman, Amara, Susan, Lang, Florian

“…The human excitatory amino acid transporter (EAAT)2 is the major glutamate carrier in the mammalian CNS. Defective expression of the transporter results in…”
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Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB by Dieter, M, Palmada, M, Rajamanickam, J, Aydin, A, Busjahn, A, Boehmer, C, Luft, F.C, Lang, F

“…Objectives: Serum‐ and glucocorticoid‐inducible kinase 1 (SGK1) inhibits the ubiquitin ligase neuronal cell expressed developmentally downregulated 4‐2…”
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Modulation of the Voltage-Gated Potassium Channel Kv1.5 by the SGK1 Protein Kinase Involves Inhibition of Channel Ubiquitination by Boehmer, Christoph, Laufer, Jörg, Jeyaraj, Sankarganesh, Klaus, Fabian, Lindner, Ricco, Lang, Florian, Palmada, Monica

“…The serum and glucocorticoid inducible kinase SGK1 is involved in dexamethasone-induced inhibition of insulin secretion by increasing voltage-gated potassium…”
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EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase by Rajamanickam, Jeyaganesh, Palmada, Monica, Lang, Florian, Boehmer, Christoph

“…EAAT4 (SLC1A6) is a Purkinje‐Cell‐specific post‐synaptic excitatory amino acid transporter that plays a major role in clearing synaptic glutamate. EAAT4…”
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The Peptide Transporter PEPT2 is Targeted by the Protein Kinase SGK1 and the Scaffold Protein NHERF2 by Boehmer, Christoph, Palmada, Monica, Klaus, Fabian, Jeyaraj, Sankarganesh, Lindner, Ricco, Laufer, Jörg, Daniel, Hannelore, Lang, Florian

“…PEPT1 and PEPT2 are members of the family of proton-dependent oligopeptide transporters that mediate electrogenic uphill transport of small peptides and…”
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Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4‐2 and the serum and glucocorticoid‐inducible kinase isoforms SGK1/3 and protein kinase B by Boehmer, Christoph, Henke, Guido, Schniepp, Roman, Palmada, Monica, Rothstein, Jeffrey D., Bröer, Stefan, Lang, Florian

“…Surface expression of the glial glutamate transporter EAAT1 is stimulated by insulin‐like growth factor 1 through activation of phosphatidylinositol‐3‐kinase…”
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SGK1 Kinase Upregulates GLUT1 Activity and Plasma Membrane Expression by PALMADA, Monica, BOEHMER, Christoph, AKEL, Ahmad, RAJAMANICKAM, Jeyaganesh, JEYARAJ, Sankarganesh, KELLER, Konrad, LANG, Florian

“…SGK1 Kinase Upregulates GLUT1 Activity and Plasma Membrane Expression Monica Palmada 1 , Christoph Boehmer 1 , Ahmad Akel 1 , Jeyaganesh Rajamanickam 1 ,…”
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The serum and glucocorticoid-inducible kinase SGK1 and the Na+/H+ exchange regulating factor NHERF2 synergize to stimulate the renal outer medullary K+ channel ROMK1 by YUN, C. Chris, PALMADA, Monica, KORBMACHER, Christoph, COHEN, Philip, PEARCE, David, LANG, Florian, EMBARK, Hamdy M, FEDORENKO, Olga, YUXI FENG, HENKE, Guido, SETIAWAN, Iwan, BOEHMER, Christoph, WEINMAN, Edward J, SANDRASAGRA, Sabrina

“…Mineralocorticoids stimulate Na(+) reabsorption and K(+) secretion in principal cells of connecting tubule and collecting duct. The involved ion channels are…”
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Cloning, Heterologous Expression, and Characterization of Three Aquaglyceroporins from Trypanosoma brucei by Uzcategui, Nestor L, Szallies, Alexander, Pavlovic-Djuranovic, Slavica, Palmada, Monica, Figarella, Katherine, Boehmer, Christoph, Lang, Florian, Beitz, Eric, Duszenko, Michael

“…Trypanosoma brucei , causative for African sleeping sickness, relies exclusively on glycolysis for ATP production. Under anaerobic conditions, glucose is…”
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The C-Terminal PDZ-Binding Motif in the Kv1.5 Potassium Channel Governs its Modulation by the Na+/H+ Exchanger Regulatory Factor 2 by Laufer, Jörg, Boehmer, Christoph, Jeyaraj, Sankarganesh, Knüwer, Martin, Klaus, Fabian, Lindner, Ricco, Palmada, Monica, Lang, Florian

“…Kv1.5 belongs to the family of voltage-gated potassium (Kv) channels and contains a N- and a C-terminal PDZ-binding motif that might be recognized by PDZ…”
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Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB by Boehmer, Christoph, Okur, Ferah, Setiawan, Iwan, Bröer, Stefan, Lang, F

“…The amino acid transporter SN1 with substrate specificity identical to the amino acid transport system N is expressed mainly in astrocytes and hepatocytes…”
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Activating Mutation of the Renal Epithelial Chloride Channel ClC-Kb Predisposing to Hypertension by Jeck, Nikola, Waldegger, Siegfried, Lampert, Angelika, Boehmer, Christoph, Waldegger, Petra, Lang, Philipp A, Wissinger, Bernd, Friedrich, Björn, Risler, Teut, Moehle, Robert, Lang, Undine E, Zill, Peter, Bondy, Brigitta, Schaeffeler, Elke, Asante-Poku, Stephen, Seyberth, Hannsjörg, Schwab, Matthias, Lang, Florian

“…The chloride channel ClC-Kb is expressed in the basolateral cell membrane of the distal nephron and participates in renal NaCl reabsorption. Loss-of-function…”
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Serum- and Glucocorticoid-Inducible Kinase 1 Mediates Salt Sensitivity of Glucose Tolerance by Boini, Krishna M, Hennige, Anita M, Huang, Dan Yang, Friedrich, Björn, Palmada, Monica, Boehmer, Christoph, Grahammer, Florian, Artunc, Ferruh, Ullrich, Susanne, Avram, Diana, Osswald, Hartmut, Wulff, Peer, Kuhl, Dietmar, Vallon, Volker, Häring, Hans-Ulrich, Lang, Florian

“…Serum- and Glucocorticoid-Inducible Kinase 1 Mediates Salt Sensitivity of Glucose Tolerance Krishna M. Boini 1 2 , Anita M. Hennige 3 , Dan Yang Huang 2 ,…”
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Regulation of the excitatory amino acid transporter EAAT5 by the serum and glucocorticoid dependent kinases SGK1 and SGK3 by Boehmer, Christoph, Rajamanickam, Jeyaganesh, Schniepp, Roman, Kohler, Konrad, Wulff, Peer, Kuhl, Dietmar, Palmada, Monica, Lang, Florian

“…In the mammalian retina, glutamate re-uptake is mediated by the sodium dependent cotransport systems EAAT1-5 thus terminating neuronal excitation and…”
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Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes by Embark, Hamdy M, Setiawan, Iwan, Poppendieck, Susanne, van de Graaf, Stan F J, Boehmer, Christoph, Palmada, Monica, Wieder, Thomas, Gerstberger, Ruediger, Cohen, Philip, Yun, C Chris, Bindels, René J M, Lang, Florian

“…The epithelial Ca2+ channel TRPV5 (ECaC1) plays a key role in renal and intestinal Ca2+ (re)absorption and is thus regulated by 1,25(OH) 2D3. The present study…”
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CLH-3, a ClC-2 anion channel ortholog activated during meiotic maturation in C. elegans oocytes by Rutledge, E, Bianchi, L, Christensen, M, Boehmer, C, Morrison, R, Broslat, A, Beld, A M, George, A L, Greenstein, D, Strange, K

“…ClC anion channels are ubiquitous and have been identified in organisms as diverse as bacteria and humans. Despite their widespread expression and likely…”
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Stimulation of renal Na + dicarboxylate cotransporter 1 by Na +/H + exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B by Boehmer, Christoph, Embark, Hamdy M, Bauer, Anna, Palmada, Monica, Yun, Chris H, Weinman, Edward J, Endou, Hitoshi, Cohen, Philip, Lahme, Sven, Bichler, Karl-Horst, Lang, Florian

“…Renal tubular citrate transport is accomplished by electrogenic Na + coupled dicarboxylate transporter NaDC-1, a carrier subjected to regulation by acidosis…”
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Functional characterization of a Na+–phosphate cotransporter (NaPi-II) from zebrafish and identification of related transcripts by Nalbant, Perihan, Boehmer, Christoph, Dehmelt, Leif, Wehner, Frank, Werner, Andreas

“…We report the molecular identification of a Na + -P i (inorganic phosphate) cotransport system of the NaP i -II protein family from zebrafish intestine…”
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Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs by Gulbins, Erich, Palmada, Monica, Reichel, Martin, Lüth, Anja, Böhmer, Christoph, Amato, Davide, Müller, Christian P, Tischbirek, Carsten H, Groemer, Teja W, Tabatabai, Ghazaleh, Becker, Katrin A, Tripal, Philipp, Staedtler, Sven, Ackermann, Teresa F, van Brederode, Johannes, Alzheimer, Christian, Weller, Michael, Lang, Undine E, Kleuser, Burkhard, Grassmé, Heike, Kornhuber, Johannes

“…Depression is a debilitating condition for which new treatments are sorely needed. Now, Erich Gulbins and his colleagues report that reducing ceramide levels…”
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