Search Results - "Boehme, Julia D"
-
1
Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge
Published in PLoS pathogens (16-09-2019)“…Cytomegalovirus (CMV) is a ubiquitous β-herpesvirus that establishes life-long latent infection in a high percentage of the population worldwide. CMV induces…”
Get full text
Journal Article -
2
Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
Published in Scientific reports (28-11-2023)“…Influenza A virus (IAV) defective interfering particles (DIPs) are considered as new promising antiviral agents. Conventional DIPs (cDIPs) contain a deletion…”
Get full text
Journal Article -
3
Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation via Toll-Like Receptor 7
Published in Frontiers in immunology (13-02-2018)“…The innate immune system senses influenza A virus (IAV) through different pathogen-recognition receptors including Toll-like receptor 7 (TLR7). Downstream of…”
Get full text
Journal Article -
4
In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection
Published in Frontiers in immunology (14-08-2019)“…An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a…”
Get full text
Journal Article -
5
Chronic lung inflammation primes humoral immunity and augments antipneumococcal resistance
Published in Scientific reports (10-07-2017)“…Airway epithelial cells (AECs) display remarkable plasticity in response to infectious stimuli and their functional adaptations are critical for antimicrobial…”
Get full text
Journal Article -
6
Respiratory Bordetella bronchiseptica Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice
Published in International journal of molecular sciences (01-09-2018)“…The respiratory tract is constantly exposed to the environment and displays a favorable niche for colonizing microorganisms. However, the effects of…”
Get full text
Journal Article -
7
CD47 restricts antiviral function of alveolar macrophages during influenza virus infection
Published in iScience (22-12-2022)“…CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully…”
Get full text
Journal Article -
8
Predicting Influenza A Virus Infection in the Lung from Hematological Data with Machine Learning
Published in mSystems (20-12-2022)“…The tracking of pathogen burden and host responses with minimally invasive methods during respiratory infections is central for monitoring disease development…”
Get full text
Journal Article -
9
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade
Published in Immunity (Cambridge, Mass.) (13-04-2021)“…Loss of lymphocytes, particularly T cell apoptosis, is a central pathological event after severe tissue injury that is associated with increased susceptibility…”
Get full text
Journal Article -
10
Altered nasal microbiota in asthmatic patients is not related to changes in secretory immunity in the nasopharynx
Published in Clinical and experimental allergy (01-10-2022)Get full text
Journal Article -
11
NMP4: a nuclear driver of innate inflammatory responses during influenza A virus infection
Published in Cellular & molecular immunology (01-12-2020)Get full text
Journal Article -
12
Exogenous and Endogenous Triggers Differentially Stimulate Pigr Expression and Antibacterial Secretory Immunity in the Murine Respiratory Tract
Published in Lung (01-02-2022)“…Purpose Transport of secretory immunoglobulin A (SIgA) through the airway epithelial cell barrier into the mucosal lumen by the polymeric immunoglobulin…”
Get full text
Journal Article -
13
IL-33: a jack of all trades in the orchestration of respiratory antibacterial immunity
Published in Cellular & molecular immunology (01-11-2017)Get full text
Journal Article -
14
IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-2024)“…IL-22 plays a critical role in defending against mucosal infections, but how IL-22 production is regulated is incompletely understood. Here, we show that mice…”
Get full text
Journal Article