Search Results - "Boedeker, Edgar C"
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Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Published in Proceedings of the National Academy of Sciences - PNAS (21-08-2007)“…The two primary human inflammatory bowel diseases, Crohn's disease (CD) and ulcerative colitis (UC), are idiopathic relapsing disorders characterized by…”
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The QseC Sensor Kinase: A Bacterial Adrenergic Receptor
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-2006)“…Quorum sensing is a cell-to-cell signaling mechanism in which bacteria respond to hormone-like molecules called autoinducers (AIs). The AI-3 quorum-sensing…”
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Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition
Published in PloS one (13-06-2012)“…We tested the hypothesis that Crohn's disease (CD)-related genetic polymorphisms involved in host innate immunity are associated with shifts in human…”
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Role of Host Xanthine Oxidase in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli
Published in Infection and Immunity (01-04-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Virulence Inhibition by Zinc in Shiga-Toxigenic Escherichia coli
Published in Infection and Immunity (01-04-2011)“…Previously, our laboratories reported that zinc inhibited expression of several important virulence factors in enteropathogenic Escherichia coli (EPEC) and…”
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Identification of Candidate Adherent-Invasive E. coli Signature Transcripts by Genomic/Transcriptomic Analysis
Published in PloS one (30-06-2015)“…Adherent-invasive Escherichia coli (AIEC) strains are detected more frequently within mucosal lesions of patients with Crohn's disease (CD). The AIEC phenotype…”
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Serine protease EspP from enterohemorrhagic Escherichia coli is sufficient to induce shiga toxin macropinocytosis in intestinal epithelium
Published in PloS one (18-07-2013)“…Life-threatening intestinal and systemic effects of the Shiga toxins produced by enterohemorrhagic Escherichia coli (EHEC) require toxin uptake and…”
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Effect of Zinc in Enteropathogenic Escherichia coli Infection
Published in Infection and Immunity (01-12-2007)“…Enteropathogenic Escherichia coli (EPEC) infection triggers the release of ATP from host intestinal cells, and the ATP is broken down to ADP, AMP, and…”
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Correction: Identification of Candidate Adherent-Invasive E. coli Signature Transcripts by Genomic/Transcriptomic Analysis
Published in PloS one (28-07-2015)Get full text
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A Vibrio cholerae Pathogenicity Island Associated with Epidemic and Pandemic Strains
Published in Proceedings of the National Academy of Sciences - PNAS (17-03-1998)“…The bacterial species Vibrio cholerae includes harmless aquatic strains as well as strains capable of causing epidemics and global pandemics of cholera. While…”
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Disease phenotype and genotype are associated with shifts in intestinal‐associated microbiota in inflammatory bowel diseases
Published in Inflammatory bowel diseases (01-01-2011)“…Background: Abnormal host–microbe interactions are implicated in the pathogenesis of inflammatory bowel diseases. Previous 16S rRNA sequence analysis of…”
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Development of live attenuated bacterial vaccines targeting Escherichia coli heat-labile and heat-stable enterotoxins
Published in Veterinary microbiology (01-04-2017)“…•All Enterotoxigenic Escherichia coli (ETEC) are defined by the production of heat labile (LT) and/or stable (ST) toxins.•There is no broadly protective human…”
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A New Mouse Model for Human Enterotoxigenic E. coli (ETEC) Infection: Effect of the Gut Microbiota on Intestinal Secretion
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Protection against Hemorrhagic Colitis in an Animal Model by Oral Immunization with Isogeneic Rabbit Enteropathogenic Escherichia coli Attenuated by Truncating Intimin
Published in Infection and Immunity (01-10-2005)“…Strains of Shiga toxin (Stx)-producing Escherichia coli, also called enterohemorrhagic E. coli (EHEC), are important food-borne pathogens for humans. Most EHEC…”
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Secretion of the Shiga toxin B subunit (Stx1B) via an autotransporter protein optimizes the protective immune response to the antigen expressed in an attenuated E. coli (rEPEC E22Δler) vaccine strain
Published in Veterinary microbiology (01-11-2017)“…•Attenuated REPEC strains deficient in ler (a global regulator of virulence genes) are effective oral vaccines against their parent pathogens.•These attenuated…”
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Mo1948 Toward a Broadly Protective Vaccine Against Enterotoxigenic E.coli (ETEC) Infections
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2014)Get full text
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Complete Nucleotide Sequence and Analysis of the Locus of Enterocyte Effacement from Rabbit Diarrheagenic Escherichia coli RDEC-1
Published in Infection and Immunity (01-04-2001)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Attenuated Escherichia coli strains expressing the colonization factor antigen I (CFA/I) and a detoxified heat-labile enterotoxin (LThK63) enhance clearance of ETEC from the lungs of mice and protect mice from intestinal ETEC colonization and LT-induced fluid accumulation
Published in Veterinary immunology and immunopathology (15-03-2013)“…Although enterotoxigenic Escherichia coli (ETEC) infections are important causes of infantile and traveler's diarrhea there is no licensed vaccine available…”
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Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections
Published in Current opinion in gastroenterology (01-01-2008)“…PURPOSE OF REVIEWShiga toxin-producing Escherichia coli cause hemorrhagic colitis and hemolytic uremic syndrome. We will summarize the literature on incidence…”
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