Search Results - "Boeckers, T M"

Identification and functional characterization of rare SHANK2 variants in schizophrenia by Peykov, S, Berkel, S, Schoen, M, Weiss, K, Degenhardt, F, Strohmaier, J, Weiss, B, Proepper, C, Schratt, G, Nöthen, M M, Boeckers, T M, Rietschel, M, Rappold, G A

“…Recent genetic data on schizophrenia (SCZ) have suggested that proteins of the postsynaptic density of excitatory synapses have a role in its etiology…”
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Temporal-spatial expression and novel biochemical properties of the memory-related protein KIBRA by Johannsen, S, Duning, K, Pavenstädt, H, Kremerskothen, J, Boeckers, T.M

“…Abstract The ability of the mammalian brain to store and recall information is based on synaptic plasticity due to constant remodeling of synaptic contacts…”
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The Kvβ2 subunit of voltage-gated potassium channels is interacting with ProSAP2/Shank3 in the PSD by Proepper, C, Putz, S, Russell, R, Boeckers, T.M, Liebau, S

“…Highlights • Kvβ2 is an interaction partner of ProSAP2/Shank3. • Kvβ2 and ProSAP2Shank3 colocalize at the neuronal PSD. • The interacting domain of…”
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Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)—scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system by Raab, M, Boeckers, T.M, Neuhuber, W.L

“…Abstract Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3) were originally found as synapse-associated protein…”
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The postsynaptic density by Boeckers, T M

“…Glutamatergic synapses in the central nervous system are characterized by an electron-dense web underneath the postsynaptic membrane; this web is called the…”
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Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice by Vicidomini, C, Ponzoni, L, Lim, D, Schmeisser, M J, Reim, D, Morello, N, Orellana, D, Tozzi, A, Durante, V, Scalmani, P, Mantegazza, M, Genazzani, A A, Giustetto, M, Sala, M, Calabresi, P, Boeckers, T M, Sala, C, Verpelli, C

“…SHANK3 (also called PROSAP2 ) genetic haploinsufficiency is thought to be the major cause of neuropsychiatric symptoms in Phelan-McDermid syndrome (PMS). PMS…”
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Neurocan Is Dispensable for Brain Development by Zhou, Xiao-Hong, Brakebusch, Cord, Matthies, Henry, Oohashi, Toshitaka, Hirsch, Emilio, Moser, Markus, Krug, Manfred, Seidenbecher, Constanze I., Boeckers, Tobias M., Rauch, Uwe, Buettner, Reinhard, Gundelfinger, Eckart D., Fässler, Reinhard

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Kainate-induced seizures alter protein composition and N-methyl- d-aspartate receptor function of rat forebrain postsynaptic densities by Wyneken, U, Smalla, K.-H, Marengo, J.J, Soto, D, de la Cerda, A, Tischmeyer, W, Grimm, R, Boeckers, T.M, Wolf, G, Orrego, F, Gundelfinger, E.D

“…The postsynaptic density is a highly dynamic structure, which is reorganized in an activity-dependent manner. An animal model for temporal lobe epilepsy, i.e…”
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Formation and characterisation of neuromuscular junctions between hiPSC derived motoneurons and myotubes by Demestre, M., Orth, M., Föhr, K.J., Achberger, K., Ludolph, A.C., Liebau, S., Boeckers, T.M.

“…Striated skeletal muscle cells from humans represent a valuable source for in vitro studies of the motoric system as well as for pathophysiological…”
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Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice by Vicidomini, C, Ponzoni, L, Lim, D, Schmeisser, M J, Reim, D, Morello, N, Orellana, D, Tozzi, A, Durante, V, Scalmani, P, Mantegazza, M, Genazzani, A A, Giustetto, M, Sala, M, Calabresi, P, Boeckers, T M, Sala, C, Verpelli, C

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Evaluation of a curved surgical prototype in a human larynx by Schild, L. R., Boehm, F., Kienle, L., Seitz, A., Kahrs, L. A., Boeckers, T. M., Greve, J., Hoffmann, T. K., Schuler, P. J.

“…Purpose It is not always possible to create linear access to the larynx using a rigid operating laryngoscope for microlaryngoscopy. In this study, we evaluate…”
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Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation by Raynaud, Fabrice, Janossy, Andrea, Dahl, Janine, Bertaso, Federica, Perroy, Julie, Varrault, Annie, Vidal, Michel, Worley, Paul F, Boeckers, Tobias M, Bockaert, Joël, Marin, Philippe, Fagni, Laurent, Homburger, Vincent

“…Synaptic long-term potentiation (LTP) is a key mechanism involved in learning and memory, and its alteration is associated with mental disorders. Shank3 is a…”
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Aripiprazole and Riluzole treatment alters behavior and neurometabolites in young ADHD rats: a longitudinal 1 H-NMR spectroscopy study at 11.7T by Rizzo, F, Abaei, A, Nespoli, E, Fegert, J M, Hengerer, B, Rasche, V, Boeckers, T M

“…Attention deficit hyperactivity disorder (ADHD), Tourette syndrome (TS) as well as obsessive compulsive disorder (OCD) are co-occurring neurodevelopmental…”
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Homer1b/c clustering is impaired in Phelan-McDermid Syndrome iPSCs derived neurons by Vicidomini, C, Ponzoni, L, Lim, D, Schmeisser, M J, Reim, D, Morello, N, Orellana, D, Tozzi, A, Durante, V, Scalmani, P, Mantegazza, M, Genazzani, A A, Giustetto, M, Sala, M, Calabresi, P, Boeckers, T M, Sala, C, Verpelli, C

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Effect of didactically qualified student tutors on their tutees’ academic performance and tutor evaluation in the gross anatomy course by Horneffer, A., Fassnacht, U., Oechsner, W., Huber-Lang, M., Boeckers, T.M., Boeckers, A.

“…Peer teaching is widely applied in medical education, anatomists having a notably long tradition in cooperating with student tutors in the dissection course…”
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The postsynaptic density protein Abelson interactor protein 1 interacts with the motor protein Kinesin family member 26B in hippocampal neurons by Heinrich, J, Proepper, C, Schmidt, T, Linta, L, Liebau, S, Boeckers, T.M

“…Highlights ► Kif26B is expressed in the central nervous system. ► Abi-1 is a direct protein–protein interaction partner of Kif26B. ► Kif26B plays a crucial…”
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ProSAP/Shank proteins – a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease by Boeckers, Tobias M., Bockmann, Jürgen, Kreutz, Michael R., Gundelfinger, Eckart D.

“…The postsynaptic density (PSD) is a specialized electron‐dense structure underneath the postsynaptic plasmamembrane of excitatory synapses. It is thought to…”
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Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance by Duning, K, Wennmann, D O, Bokemeyer, A, Reissner, C, Wersching, H, Thomas, C, Buschert, J, Guske, K, Franzke, V, Flöel, A, Lohmann, H, Knecht, S, Brand, S-M, Pöter, M, Rescher, U, Missler, M, Seelheim, P, Pröpper, C, Boeckers, T M, Makuch, L, Huganir, R, Weide, T, Brand, E, Pavenstädt, H, Kremerskothen, J

“…The human KIBRA gene has been linked to human cognition through a lead intronic single-nucleotide polymorphism (SNP; rs17070145) that is associated with…”
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Linkage of the Actin Cytoskeleton to the Postsynaptic Density via Direct Interactions of Abp1 with the ProSAP/Shank Family by Qualmann, Britta, Boeckers, Tobias M, Jeromin, Monika, Gundelfinger, Eckart D, Kessels, Michael M

“…Synaptic contacts contain elaborate cytomatrices on both sides of the synaptic cleft, which are believed to organize and link the different synaptic functions…”
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Methylphenidate exerts no neurotoxic, but neuroprotective effects in vitro by Ludolph, A G, Schaz, U, Storch, A, Liebau, S, Fegert, J M, Boeckers, T M

“…Methylphenidate (MPH) is the most common used drug in child and adolescent psychiatry. Despite of this fact, however, little is known about its exact…”
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