Search Results - "Bodyak, N."

Performance of mice in an automated olfactometer : Odor detection, discrimination and odor memory by BODYAK, N, SLOTNICK, B

“…Mice were trained on a variety of odor detection and discrimination tasks in 100- or 200-trial sessions using a go, no-go discrete trials operant conditioning…”
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Renal and Cardiac Endothelial Heterogeneity Impact Acute Vascular Rejection in Pig‐to‐Baboon Xenotransplantation by Knosalla, C., Yazawa, K., Behdad, A., Bodyak, N., Shang, H., Bühler, L., Houser, S., Gollackner, B., Griesemer, A., Schmitt‐Knosalla, I., Schuurman, H.‐J., Awwad, M., Sachs, D. H., Cooper, D. K. C., Yamada, K., Usheva, A., Robson, S. C.

“…Xenograft outcomes are dictated by xenoantigen expression, for example, Gal α1, 3Gal (Gal), but might also depend on differing vascular responses. We…”
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Gene expression profiling of the aging mouse cardiac myocytes by Bodyak, Natalya, Kang, Peter M., Hiromura, Makoto, Sulijoadikusumo, Indra, Horikoshi, Nobuo, Khrapko, Konstantin, Usheva, Anny

“…Heart disease remains the most frequent cause of death in the general population with increasing incidence in the elderly population. The pathologic failure of…”
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Quantification and sequencing of somatic deleted mtDNA in single cells : evidence for partially duplicated mtDNA in aged human tissues by BODYAK, Natalya D, NEKHAEVA, Ekaterina, WEI, Jeanne Y, KHRAPKO, Konstantin

“…Single-cell PCR of the whole mitochondrial genome provides detailed information about intracellular clonal expansions of deleted mitochondrial DNA…”
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High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection by Nekhaeva, Ekaterina, Thilly, William G, Khrapko, Konstantin, Herrero-Jimenez, Pablo, Coller, Hilary A, Bodyak, Natalya D

“…Researchers in several laboratories have reported a high frequency of homoplasmic mitochondrial DNA (mtDNA) mutations in human tumors. This observation has…”
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Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions by Khrapko, Konstantin, Bodyak, Natalya, Thilly, William G., van Orsouw, Nathalie J., Zhang, Xiaomin, Coller, Hilary A., Perls, Thomas T., Upton, Melissa, Vijg, Jan, Wei, Jeanne Y.

“…Quantitative information on the cell-to-cell distribution of all possible mitochondrial DNA (mtDNA) mutations in young and aged tissues is needed to assess the…”
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Clonally Expanded mtDNA Point Mutations are Abundant in Individual Cells of Human Tissues by Nekhaeva, Ekaterina, Bodyak, Natalya D., Kraytsberg, Yevgenya, McGrath, Sean B., Van Orsouw, Nathalie J., Pluzhnikov, Anna, Wei, Jeanne Y., Vijg, Jan, Khrapko, Konstantin

“…Using single-cell sequence analysis, we discovered that a high proportion of cells in tissues as diverse as buccal epithelium and heart muscle contain high…”
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Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury by Bach, Fritz H, Choi, Augustine M.K, Otterbein, Leo E, Zuckerbraun, Brian S, Haga, Manabu, Liu, Fang, Song, Ruiping, Usheva, Anny, Stachulak, Christina, Bodyak, Natalya, Smith, R. Neal, Csizmadia, Eva, Tyagi, Shivraj, Akamatsu, Yorihiro, Flavell, Richard J, Billiar, Timothy R, Tzeng, Edith, Soares, Miguel P

“…Carbon monoxide (CO), one of the products of heme oxygenase action on heme, prevents arteriosclerotic lesions that occur following aorta transplantation;…”
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Abstract P4-14-28: XMT-1522 induces tumor regressions in pre-clinical models representing HER2-positive and HER2 low-expressing breast cancer by Bergstrom, DA, Bodyak, N, Park, PU, Yurkovetskiy, A, DeVit, M, Yin, M, Poling, L, Thomas, JD, Gumerov, D, Xiao, D, Ter-Ovanesyan, E, Qin, L, Uttard, A, Johnson, A, Lowinger, TB

“…Abstract XMT-1522 is an anti-HER2 antibody-drug conjugate (ADC) comprised of a novel anti-HER2 antibody (HT-19) and the Dolaflexin ADC platform, which allows…”
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Genetic expression profiles during physiological and pathological cardiac hypertrophy and heart failure in rats by Kong, Sek Won, Bodyak, Natalya, Yue, Patrick, Liu, Zhilin, Brown, Jeffrey, Izumo, Seigo, Kang, Peter M

“…Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts Cardiac hypertrophy is a complex and…”
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Regulation of Vascular Endothelial Growth Factor Expression and Vascularization in the Myocardium by Insulin Receptor and PI3K/Akt Pathways in Insulin Resistance and Ischemia by He, Zhiheng, Opland, Darren M, Way, Kerrie J, Ueki, Kohjiro, Bodyak, Natalya, Kang, Peter M, Izumo, Seigo, Kulkarni, Rohit N, Wang, Bo, Liao, Ronglih, Kahn, C Ronald, King, George L

“…OBJECTIVE—This study characterized the role of insulin receptors and resistance on vascular endothelial growth factor (VEGF) expression and myocardial…”
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Odor Discrimination and Odor Quality Perception in Rats with Disruption of Connections between the Olfactory Epithelium and Olfactory Bulbs by Slotnick, Burton, Bodyak, Natalya

“…Rats were trained using olfactometry and operant conditioning to discriminate among homologous fatty acids, homologous aldehydes, and a series of unrelated…”
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Alterations in apoptosis regulatory factors during hypertrophy and heart failure by Kang, Peter M, Yue, Patrick, Liu, Zhilin, Tarnavski, Oleg, Bodyak, Natalya, Izumo, Seigo

“…Cardiac hypertrophy from pathological stimuli often proceeds to heart failure, whereas cardiac hypertrophy from physiological stimuli does not. In this study,…”
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Does Intranasal Application of Zinc Sulfate Produce Anosmia in the Rat? by Slotnick, Burton, Glover, Polly, Bodyak, Natalya

“…Transport of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) from olfactory sensory neurons to the olfactory bulb as well as odor detection and…”
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Olfactory Marker Protein Immunohistochemistry and the Anterograde Transport of Horseradish Peroxidase as Indices of Damage to the Olfactory Epithelium by Slotnick, Burton, Bodyak, Natalya, Davis, Barry J.

“…The present study compared the relative effectiveness of wheatgerm agglutinin–horseradish peroxidase (WGA–HRP) and olfactory marker protein (OMP) in detecting…”
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Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms by Coller, Hilary A, Bodyak, Natalya D, Khrapko, Konstantin

“…It has been proposed that age-dependent accumulation of somatic mutations in mtDNA is responsible for some aspects of the aging process. However, most cells…”
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Mutation and intracellular clonal expansion of mitochondrial genomes: two synergistic components of the aging process? by Kraytsberg, Yevgenya, Nekhaeva, Ekaterina, Bodyak, Natalya B, Khrapko, Konstantin

“…The foundations of the Mitochondrial mutational theory of aging include two assumptions: the high abundance of mitochondrial mutations and their ability to…”
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Harderian gland ultrastructure of the black sea bottlenose dolphin (Tursiops truncatus ponticus) by Bodyak, N D, Stepanova, L V

“…Examination of the Harderian gland structure of the Black Sea bottlenose dolphin, Tursiops truncatus ponticus, at macroscopic, microscopic, and electron…”
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The harderian gland in mammals: The biochemical and physiological aspects by Bodiak, N D

“…This review continues analysis of the published data on the Harderian gland in mammals (the first part described the structural properties). Here, biochemical…”
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