Search Results - "Body, Jean‐Jacques"
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Management of bone health in solid tumours: From bisphosphonates to a monoclonal antibody
Published in Cancer treatment reviews (01-06-2019)“…•Bone is a common site of metastasis, particularly in breast and prostate cancer.•Bisphosphonates reduce skeletal-related events in patients with bone…”
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Prediction of an Imminent Fracture After an Index Fracture – Models Derived From the Frisbee Cohort
Published in Journal of bone and mineral research (01-01-2022)“…ABSTRACT Patients who sustain a fracture are at greatest risk of recurrent fracture during the next 2 years. We propose three models to identify subjects most…”
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Osteonecrosis of the Jaw and Antiresorptive Agents in Benign and Malignant Diseases: A Critical Review Organized by the ECTS
Published in The journal of clinical endocrinology and metabolism (19-04-2022)“…Antiresorptive therapy significantly reduces fracture risk in patients with benign bone disease and skeletal-related events (SREs) in patients with bone…”
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Global guidance for the recognition, diagnosis, and management of tumor‐induced osteomalacia
Published in Journal of internal medicine (01-03-2023)“…Tumor‐induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by mesenchymal tumors that secrete fibroblast growth factor 23 (FGF23). Patients…”
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Postfracture Risk Assessment: Target the Centrally Sited Fractures First! A Substudy of NoFRACT
Published in Journal of bone and mineral research (01-04-2020)Get full text
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Denosumab Compared With Zoledronic Acid for the Treatment of Bone Metastases in Patients With Advanced Breast Cancer: A Randomized, Double-Blind Study
Published in Journal of clinical oncology (10-12-2010)“…This randomized study compared denosumab, a fully human monoclonal antibody against receptor activator of nuclear factor κ B (RANK) ligand, with zoledronic…”
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Effects of Dairy Products Consumption on Health: Benefits and Beliefs—A Commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
Published in Calcified tissue international (2016)“…Dairy products provide a package of essential nutrients that is difficult to obtain in low-dairy or dairy-free diets, and for many people it is not possible to…”
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Increased fracture rate in women with breast cancer: a review of the hidden risk
Published in BMC cancer (29-08-2011)“…Women with breast cancer, particularly individuals diagnosed at a relatively early age, have an increased incidence of fractures. Fractures can have serious…”
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Randomized Phase II Trial of Denosumab in Patients With Bone Metastases From Prostate Cancer, Breast Cancer, or Other Neoplasms After Intravenous Bisphosphonates
Published in Journal of clinical oncology (01-04-2009)“…Patients with bone metastases and elevated urinary N-telopeptide (uNTx), representing excessive bone resorption, are at increased risk for skeletal-related…”
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Osteonecrosis of the jaw related to non-antiresorptive medications: a systematic review
Published in Supportive care in cancer (01-02-2019)“…Introduction The reporting of osteonecrosis of the jaw (ONJ) related to anticancer agents without known antiresorptive properties (non-antiresorptives), such…”
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Prevention and Treatment of Glucocorticoid-Induced Osteoporosis in Adults: Consensus Recommendations From the Belgian Bone Club
Published in Frontiers in endocrinology (Lausanne) (09-06-2022)“…Glucocorticoids are effective immunomodulatory drugs used for many inflammatory disorders as well as in transplant recipients. However, both iatrogenic and…”
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Pain Outcomes in Patients With Advanced Breast Cancer and Bone Metastases: Results From a Randomized, Double-Blind Study of Denosumab and Zoledronic Acid
Published in Cancer (15-02-2013)“…In this study, the authors evaluated the effect of denosumab versus zoledronic acid (ZA) on pain in patients with advanced breast cancer and bone metastases…”
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Updated guidance on the management of cancer treatment-induced bone loss (CTIBL) in pre- and postmenopausal women with early-stage breast cancer
Published in Journal of bone oncology (01-06-2021)“…•Aromatase inhibitors induce bone loss and increase fracture risk in early-stage breast cancer women.•BMD T-score < -2.0 SD or ≥ 2 clinical risk factors are an…”
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Effects of denosumab in patients with bone metastases with and without previous bisphosphonate exposure
Published in Journal of bone and mineral research (01-03-2010)“…Bone metastases place patients at increased risk of skeletal‐related events (SREs), including pathologic fractures, spinal cord compression, severe pain…”
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Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ESCEO, IMS, and SIOG
Published in Journal of bone oncology (01-06-2017)“…Several guidelines have been reported for bone-directed treatment in women with early breast cancer (EBC) for averting fractures, particularly during aromatase…”
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Randomized Active-Controlled Phase II Study of Denosumab Efficacy and Safety in Patients With Breast Cancer-Related Bone Metastases
Published in Journal of clinical oncology (01-10-2007)“…Denosumab, a fully human monoclonal antibody to receptor activator of nuclear factor-kappaB ligand, suppresses bone resorption. In this study, we evaluated the…”
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A real-world study assessing the use of bone-targeted agents and their impact on bone metastases in patients with prostate cancer treated in clinical practice in Europe
Published in Journal of bone oncology (01-02-2019)“…Bone metastases (BMs) are common in patients with prostate cancer and can lead to skeletal-related events (SREs), which are associated with increased pain and…”
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Patient preferences for treatments to delay bone metastases
Published in The Prostate (01-11-2014)“…BACKGROUND Most patients with advanced prostate cancer (PCa) develop bone metastases (BM) and present with bone complications like fracture. Bone‐targeted…”
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Bisphosphonates Induce Breast Cancer Cell Death In Vitro
Published in Journal of bone and mineral research (01-11-2000)“…Breast cancer frequently spreads to bone and is almost always associated with osteolysis. This tumor‐induced osteolysis is caused by increased osteoclastic…”
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Fibroblast growth factor 23 and its role in phosphate homeostasis
Published in European journal of endocrinology (01-01-2010)“…Phosphate homeostasis is complex and incompletely understood. The identification of different factors involved in the regulation of phosphate balance, also…”
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