Search Results - "Bodogai, Monica"

Therapeutic B-cell depletion reverses progression of Alzheimer’s disease by Kim, Ki, Wang, Xin, Ragonnaud, Emeline, Bodogai, Monica, Illouz, Tomer, DeLuca, Marisa, McDevitt, Ross A., Gusev, Fedor, Okun, Eitan, Rogaev, Evgeny, Biragyn, Arya

“…The function of B cells in Alzheimer’s disease (AD) is not fully understood. While immunoglobulins that target amyloid beta (Aβ) may interfere with plaque…”
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Daily caloric restriction limits tumor growth more effectively than caloric cycling regardless of dietary composition by Pomatto-Watson, Laura C. D., Bodogai, Monica, Bosompra, Oye, Kato, Jonathan, Wong, Sarah, Carpenter, Melissa, Duregon, Eleonora, Chowdhury, Dolly, Krishna, Priya, Ng, Sandy, Ragonnaud, Emeline, Salgado, Roberto, Gonzalez Ericsson, Paula, Diaz-Ruiz, Alberto, Bernier, Michel, Price, Nathan L., Biragyn, Arya, Longo, Valter D., de Cabo, Rafael

“…Cancer incidence increases with age and is a leading cause of death. Caloric restriction (CR) confers benefits on health and survival and delays cancer…”
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Identification of senescent cell surface targetable protein DPP4 by Kim, Kyoung Mi, Noh, Ji Heon, Bodogai, Monica, Martindale, Jennifer L, Yang, Xiaoling, Indig, Fred E, Basu, Sandip K, Ohnuma, Kei, Morimoto, Chikao, Johnson, Peter F, Biragyn, Arya, Abdelmohsen, Kotb, Gorospe, Myriam

“…Senescent cell accumulation in aging tissues is linked to age-associated diseases and declining function, prompting efforts to eliminate them. Mass…”
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Altered Extracellular Vesicle Concentration, Cargo, and Function in Diabetes by Freeman, David W, Noren Hooten, Nicole, Eitan, Erez, Green, Jamal, Mode, Nicolle A, Bodogai, Monica, Zhang, Yongqing, Lehrmann, Elin, Zonderman, Alan B, Biragyn, Arya, Egan, Josephine, Becker, Kevin G, Mattson, Mark P, Ejiogu, Ngozi, Evans, Michele K

“…Type 2 diabetes is a chronic age-associated degenerative metabolic disease that reflects relative insulin deficiency and resistance. Extracellular vesicles…”
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Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells by Lee-Chang, Catalina, Bodogai, Monica, Martin-Montalvo, Alejandro, Wejksza, Katarzyna, Sanghvi, Mitesh, Moaddel, Ruin, de Cabo, Rafael, Biragyn, Arya

“…We reported previously that tumor-evoked regulatory B cells (tBregs) play an essential role in breast cancer lung metastasis by inducing TGF-β-dependent…”
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Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes by Eitan, Erez, Green, Jamal, Bodogai, Monica, Mode, Nicolle A., Bæk, Rikke, Jørgensen, Malene M., Freeman, David W., Witwer, Kenneth W., Zonderman, Alan B., Biragyn, Arya, Mattson, Mark P., Noren Hooten, Nicole, Evans, Michele K.

“…Cells release lipid-bound extracellular vesicles (EVs; exosomes, microvesicles and apoptotic bodies) containing proteins, lipids and RNAs into the circulation…”
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Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells by Bodogai, Monica, Moritoh, Kanako, Lee-Chang, Catalina, Hollander, Christine M, Sherman-Baust, Cheryl A, Wersto, Robert P, Araki, Yoshihiko, Miyoshi, Ichiro, Yang, Li, Trinchieri, Giorgio, Biragyn, Arya

“…Myeloid-derived suppressive cells (MDSC) have been reported to promote metastasis, but the loss of cancer-induced B cells/B regulatory cells (tBreg) can block…”
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Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells by Bodogai, Monica, O'Connell, Jennifer, Kim, Ki, Kim, Yoo, Moritoh, Kanako, Chen, Chen, Gusev, Fedor, Vaughan, Kelli, Shulzhenko, Natalia, Mattison, Julie A, Lee-Chang, Catalina, Chen, Weixuan, Carlson, Olga, Becker, Kevin G, Gurung, Manoj, Morgun, Andrey, White, James, Meade, Theresa, Perdue, Kathy, Mack, Matthias, Ferrucci, Luigi, Trinchieri, Giorgio, de Cabo, Rafael, Rogaev, Evgeny, Egan, Josephine, Wu, Jiejun, Biragyn, Arya

“…Aging in humans is associated with increased hyperglycemia and insulin resistance (collectively termed IR) and dysregulation of the immune system. However, the…”
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Cancer co-opts differentiation of B-cell precursors into macrophage-like cells by Chen, Chen, Park, Bongsoo, Ragonnaud, Emeline, Bodogai, Monica, Wang, Xin, Zong, Le, Lee, Jung-Min, Beerman, Isabel, Biragyn, Arya

“…We have recently reported that some cancers induce accumulation of bone marrow (BM) B-cell precursors in the spleen to convert them into metastasis-promoting,…”
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Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L by BODOGAI, Monica, CHANG, Catalina Lee, WEJKSZA, Katarzyna, JINPING LAI, MERINO, Maria, WERSTO, Robert P, GRESS, Ronald E, CHAN, Andrew C, HESDORFFER, Charles, BIRAGYN, Arya

“…The possible therapeutic benefits of B-cell depletion in combating tumoral immune escape have been debated. In support of this concept, metastasis of highly…”
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Tumor-Derived Thymic Stromal Lymphopoietin Expands Bone Marrow B-cell Precursors in Circulation to Support Metastasis by Ragonnaud, Emeline, Moritoh, Kanako, Bodogai, Monica, Gusev, Fedor, Garaud, Soizic, Chen, Chen, Wang, Xin, Baljinnyam, Tuvshintugs, Becker, Kevin G, Maul, Robert W, Willard-Gallo, Karen, Rogaev, Evgeny, Biragyn, Arya

“…Immature B cells in the bone marrow emigrate into the spleen during adult lymphopoiesis. Here, we report that emigration is shifted to earlier B-cell stages in…”
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Thymic stromal lymphopoietin is a key mediator of breast cancer progression by Olkhanud, Purevdorj B, Rochman, Yrina, Bodogai, Monica, Malchinkhuu, Enkhzol, Wejksza, Katarzyna, Xu, Mai, Gress, Ronald E, Hesdorffer, Charles, Leonard, Warren J, Biragyn, Arya

“…Inflammation is a double-edged sword that can promote or suppress cancer progression. In this study, we report that thymic stromal lymphopoietin (TSLP), an…”
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Generation and identification of tumor-evoked regulatory B cells by Biragyn, Arya, Lee-Chang, Catalina, Bodogai, Monica

“…The involvement of Bregs in cancer remains poorly understood despite their well-documented regulation of responses to the self and protection from harmful…”
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Cancer Immunotherapy: Theory and Application by Chen, Guobing, Bodogai, Monica, Tamehiro, Norimasa, Shen, Chuanlai, Dou, Jun

“…Through either strengthening the host immune responses against tumors, supplying modified immune system components, or counteracting signals produced by cancer…”
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Boosting NAD ameliorates hematopoietic impairment linked to short telomeres in vivo by Stock, Amanda J., Ayyar, Saipriya, Kashyap, Amogh, Wang, Yunong, Yanai, Hagai, Starost, Matthew F., Tanaka-Yano, Mayuri, Bodogai, Monica, Sun, Chongkui, Wang, Yajun, Gong, Yi, Puligilla, Chandrakala, Fang, Evandro F., Bohr, Vilhelm A., Liu, Yie, Beerman, Isabel

“…Short telomeres are a defining feature of telomere biology disorders (TBDs), including dyskeratosis congenita (DC), for which there is no effective general…”
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Replenishment of myeloid-derived suppressor cells (MDSCs) overrides CR-mediated protection against tumor growth in a murine model of triple-negative breast cancer by Pomatto-Watson, Laura C. D., Bodogai, Monica, Carpenter, Melissa, Chowdhury, Dolly, Krishna, Priya, Ng, Sandy, Bosompra, Oye, Kato, Jonathan, Wong, Sarah, Reyes-Sepulveda, Carlos, Bernier, Michel, Price, Nathan L., Biragyn, Arya, de Cabo, Rafael

“…Caloric restriction (CR) is the leading non-pharmacological intervention to delay induced and spontaneous tumors in pre-clinical models. These effects of CR…”
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Inhibition of lung metastasis by chemokine CCL17-mediated in vivo silencing of genes in CCR4+ Tregs by Biragyn, Arya, Bodogai, Monica, Olkhanud, Purevdorj B, Denny-Brown, Sinan R, Puri, Nitin, Ayukawa, Koichi, Kanegasaki, Shiro, Hogaboam, Cory M, Wejksza, Katarzyna, Lee-Chang, Catalina

“…Despite significant attractiveness of antisense oligonucleotide/RNAi technology, its clinical application has been precluded by a lack of methods for targeted…”
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Sperm-Derived SPANX-B Is a Clinically Relevant Tumor Antigen That Is Expressed in Human Tumors and Readily Recognized by Human CD4+ and CD8+ T Cells by ALMANZAR, Giovanni, OLKHANUD, Purevdorj B, KOUPRINA, Natalay, LARIONOV, Vladimir, BIRAGYN, Arya, BODOGAI, Monica, DELL'AGNOLA, Chiara, BAATAR, Dolgor, HEVVITT, Stephen M, GHIMENTON, Claudio, TUMMALA, Mohan K, WEERARATNA, Ashani T, HOEK, Keith Sean

“…Purpose: The sperm-derived SPANX family proteins can be found expressed in human tumors. Here, we aimed to perform a comprehensive study to evaluate…”
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The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease by Youm, Yun-Hee, Nguyen, Kim Y, Grant, Ryan W, Goldberg, Emily L, Bodogai, Monica, Kim, Dongin, D'Agostino, Dominic, Planavsky, Noah, Lupfer, Christopher, Kanneganti, Thirumala D, Kang, Seokwon, Horvath, Tamas L, Fahmy, Tarek M, Crawford, Peter A, Biragyn, Arya, Alnemri, Emad, Dixit, Vishwa Deep

“…Ketone bodies are elevated in response to fasting, a low-carbohydrate ketogenic diet or high-intensity exercise. Vishwa Deep Dixit and colleagues report that…”
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Peripherally activated brain CD8+ T cells promote AD in 5xFAD mice by Biragyn, Arya, Campbell, Britney, Bodogai, Monica, Wang, Xin, McDevitt, Ross, Konda, Kumaraswami

“…Abstract The role of the adaptive immunity in Alzheimer’s Disease (AD) remains poorly understood. Recent findings from our group, which link B cells to…”
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