Search Results - "Bodo Linz"

Unique TLR9 Activation by Helicobacter pylori Depends on the cag T4SS, But Not on VirD2 Relaxases or VirD4 Coupling Proteins by Tegtmeyer, Nicole, Linz, Bodo, Yamaoka, Yoshio, Backert, Steffen

“…The genomes of the gastric bacterial pathogen Helicobacter pylori harbor multiple type-IV secretion systems (T4SSs). Here we analyzed components of three…”
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Evolution and Role of Proteases in Campylobacter jejuni Lifestyle and Pathogenesis by Linz, Bodo, Sharafutdinov, Irshad, Tegtmeyer, Nicole, Backert, Steffen

“…Infection with the main human food-borne pathogen causes campylobacteriosis that accounts for a substantial percentage of gastrointestinal infections. The…”
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A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island by Olbermann, Patrick, Josenhans, Christine, Moodley, Yoshan, Uhr, Markus, Stamer, Christiana, Vauterin, Marc, Suerbaum, Sebastian, Achtman, Mark, Linz, Bodo

“…The Helicobacter pylori cag pathogenicity island (cagPAI) encodes a type IV secretion system. Humans infected with cagPAI-carrying H. pylori are at increased…”
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Worldwide Population Structure, Long-Term Demography, and Local Adaptation of Helicobacter pylori by Montano, Valeria, Didelot, Xavier, Foll, Matthieu, Linz, Bodo, Reinhardt, Richard, Suerbaum, Sebastian, Moodley, Yoshan, Jensen, Jeffrey D

“…Helicobacter pylori is an important human pathogen associated with serious gastric diseases. Owing to its medical importance and close relationship with its…”
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Age of the association between Helicobacter pylori and man by Moodley, Yoshan, Linz, Bodo, Bond, Robert P, Nieuwoudt, Martin, Soodyall, Himla, Schlebusch, Carina M, Bernhöft, Steffi, Hale, James, Suerbaum, Sebastian, Mugisha, Lawrence, van der Merwe, Schalk W, Achtman, Mark

“…When modern humans left Africa ca. 60,000 years ago (60 kya), they were already infected with Helicobacter pylori, and these bacteria have subsequently…”
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Helicobacter pylori’s historical journey through Siberia and the Americas by Moodley, Yoshan, Brunelli, Andrea, Ghirotto, Silvia, Klyubin, Andrey, Maady, Ayas S., Tyne, William, Muñoz-Ramirez, Zilia Y., Zhou, Zhemin, Manica, Andrea, Linz, Bodo, Achtman, Mark

“…The gastric bacterium Helicobacter pylori shares a coevolutionary history with humans that predates the out-of-Africa diaspora, and the geographical…”
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The microbiomes of blowflies and houseflies as bacterial transmission reservoirs by Junqueira, Ana Carolina M., Ratan, Aakrosh, Acerbi, Enzo, Drautz-Moses, Daniela I., Premkrishnan, Balakrishnan N. V., Costea, Paul I., Linz, Bodo, Purbojati, Rikky W., Paulo, Daniel F., Gaultier, Nicolas E., Subramanian, Poorani, Hasan, Nur A., Colwell, Rita R., Bork, Peer, Azeredo-Espin, Ana Maria L., Bryant, Donald A., Schuster, Stephan C.

“…Blowflies and houseflies are mechanical vectors inhabiting synanthropic environments around the world. They feed and breed in fecal and decaying organic…”
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Modeling Immune Evasion and Vaccine Limitations by Targeted Nasopharyngeal Bordetella pertussis Inoculation in Mice by Soumana, Illiassou Hamidou, Linz, Bodo, Dewan, Kalyan K, Sarr, Demba, Gestal, Monica C, Howard, Laura K, Caulfield, Amanda D, Rada, Balázs, Harvill, Eric T

“…Conventional pertussis animal models deliver hundreds of thousands of Bordetella pertussis bacteria deep into the lungs, rapidly inducing severe pneumonic…”
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An African origin for the intimate association between humans and Helicobacter pylori by Manica, Andrea, Roumagnac, Philippe, Falush, Daniel, Yamaoka, Yoshio, Prugnolle, Franck, Suerbaum, Sebastian, Wadstrom, Torkel, Balloux, François, Stamer, Christiana, Linz, Bodo, Moodley, Yoshan, Graham, David Y, Liu, Hua, van der Merwe, Schalk W, Achtman, Mark, Perez-Trallero, Emilio

“…Infection of the stomach by Helicobacter pylori is ubiquitous among humans. However, although H. pylori strains from different geographic areas are associated…”
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Evolution and Conservation of Bordetella Intracellular Survival in Eukaryotic Host Cells by Rivera, Israel, Linz, Bodo, Harvill, Eric T.

“…The classical bordetellae possess several partially characterized virulence mechanisms that are studied in the context of a complete extracellular life cycle…”
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Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species by Linz, Bodo, Ivanov, Yury V, Preston, Andrew, Brinkac, Lauren, Parkhill, Julian, Kim, Maria, Harris, Simon R, Goodfield, Laura L, Fry, Norman K, Gorringe, Andrew R, Nicholson, Tracy L, Register, Karen B, Losada, Liliana, Harvill, Eric T

“…The genus Bordetella consists of nine species that include important respiratory pathogens such as the 'classical' species B. bronchiseptica, B. pertussis and…”
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Two remarkable serine/leucine polymorphisms in Helicobacter pylori: functional importance for serine protease HtrA and adhesin BabA by Backert, Steffen, Tegtmeyer, Nicole, Horn, Anselm H C, Sticht, Heinrich, Linz, Bodo

“…Single nucleotide polymorphisms (SNPs) account for significant genomic variability in microbes, including the highly diverse gastric pathogen Helicobacter…”
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Peopling of the Pacific from a Bacterial Perspective by Moodley, Yoshan, Linz, Bodo, Yamaoka, Yoshio, Windsor, Helen M, Breurec, Sebastien, Wu, Jeng-Yih, Maady, Ayas, Bernhöft, Steffie, Thiberge, Jean-Michel, Phuanukoonnon, Suparat, Jobb, Gangolf, Siba, Peter, Graham, David Y, Marshall, Barry J, Achtman, Mark

“…Two prehistoric migrations peopled the Pacific. One reached New Guinea and Australia, and a second, more recent, migration extended through Melanesia and from…”
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A mutation burst during the acute phase of Helicobacter pylori infection in humans and rhesus macaques by Linz, Bodo, Windsor, Helen M., McGraw, John J., Hansen, Lori M., Gajewski, John P., Tomsho, Lynn P., Hake, Caylie M., Solnick, Jay V., Schuster, Stephan C., Marshall, Barry J.

“…The evolution rate and genetic changes that occur during chronic infection with Helicobacter pylori have been analysed, but little is known about the genomic…”
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Bordetella bronchiseptica exploits the complex life cycle of Dictyostelium discoideum as an amplifying transmission vector by Taylor-Mulneix, Dawn L, Bendor, Liron, Linz, Bodo, Rivera, Israel, Ryman, Valerie E, Dewan, Kalyan K, Wagner, Shannon M, Wilson, Emily F, Hilburger, Lindsay J, Cuff, Laura E, West, Christopher M, Harvill, Eric T

“…Multiple lines of evidence suggest that Bordetella species have a significant life stage outside of the mammalian respiratory tract that has yet to be defined…”
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Pertactin contributes to shedding and transmission of Bordetella bronchiseptica by Ma, Longhuan, Dewan, Kalyan K, Taylor-Mulneix, Dawn L, Wagner, Shannon M, Linz, Bodo, Rivera, Israel, Su, Yang, Caulfield, Amanda D, Blas-Machado, Uriel, Harvill, Eric T

“…Whooping cough is resurging in the United States despite high vaccine coverage. The rapid rise of Bordetella pertussis isolates lacking pertactin (PRN), a key…”
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Acellular Pertussis Vaccine Components: Today and Tomorrow by Dewan, Kalyan K, Linz, Bodo, DeRocco, Susan E, Harvill, Eric T

“…Pertussis is a highly communicable acute respiratory infection caused by Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks…”
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Natural History and Ecology of Interactions Between Bordetella Species and Amoeba by Ma, Longhuan, Linz, Bodo, Caulfield, Amanda D, Dewan, Kalyan K, Rivera, Israel, Harvill, Eric T

“…A variety of bacteria have evolved the ability to interact with environmental phagocytic predators such as amoebae, which may have facilitated their subsequent…”
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Early and late genome-wide gastric epithelial transcriptome response during infection with the human carcinogen Helicobacter pylori by Sharafutdinov, Irshad, Ekici, Arif, Vieth, Michael, Backert, Steffen, Linz, Bodo

“…Infection of the stomach by is a major risk factor for the development of gastric cancer. Colonization of the gastric epithelium leads to the activation of…”
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Conservation of Ancient Genetic Pathways for Intracellular Persistence Among Animal Pathogenic Bordetellae by Rivera, Israel, Linz, Bodo, Dewan, Kalyan K, Ma, Longhuan, Rice, Christopher A, Kyle, Dennis E, Harvill, Eric T

“…Animal and human pathogens of the genus are not commonly considered to be intracellular pathogens, although members of the closely related classical…”
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