Search Results - "Bodles, Angela M"

Retinol Binding Protein 4 Expression in Humans: Relationship to Insulin Resistance, Inflammation, and Response to Pioglitazone by Yao-Borengasser, Aiwei, Varma, Vijayalakshmi, Bodles, Angela M., Rasouli, Neda, Phanavanh, Bounleut, Lee, Mi-Jeong, Starks, Tasha, Kern, Leslie M., Spencer, Horace J., Rashidi, Amir Adel, McGehee, Robert E., Fried, Susan K., Kern, Philip A.

“…Context: Retinol binding protein 4 (RBP4) was recently found to be expressed and secreted by adipose tissue, and was strongly associated with insulin…”
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Human Visfatin Expression: Relationship to Insulin Sensitivity, Intramyocellular Lipids, and Inflammation by Varma, Vijayalakshmi, Yao-Borengasser, Aiwei, Rasouli, Neda, Bodles, Angela M., Phanavanh, Bounleut, Lee, Mi-Jeong, Starks, Tasha, Kern, Leslie M., Spencer, Horace J., McGehee, Robert E., Fried, Susan K., Kern, Philip A.

“…Context: Visfatin (VF) is a recently described adipokine preferentially secreted by visceral adipose tissue (VAT) with insulin mimetic properties. Objective:…”
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Thrombospondin-1 Is an Adipokine Associated With Obesity, Adipose Inflammation, and Insulin Resistance by VARMA, Vijayalakshmi, YAO-BORENGASSER, Aiwei, FRIED, Susan K, MCGEHEE, Robert E, PETERSON, Charlotte A, KERN, Philip A, BODIES, Angela M, RASOULI, Neda, PHANAVANH, Bounleut, NOLEN, Greg T, KERN, Emily M, NAGARAJAN, Radhakrishnan, SPENCER, Horace J, LEE, Mi-Jeong

“…Thrombospondin-1 Is an Adipokine Associated With Obesity, Adipose Inflammation, and Insulin Resistance Vijayalakshmi Varma 1 , Aiwei Yao-Borengasser 1 , Angela…”
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Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes by Bodles, Angela M, Banga, Anannya, Rasouli, Neda, Ono, Fumiyo, Kern, Philip A, Owens, Randall J

“…Adiponectin is an adipocyte-derived serum protein that plays important roles in energy homeostasis, obesity, and insulin sensitivity. Using sucrose gradients…”
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Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide by Wu, Sheng-Zhou, Bodles, Angela M, Porter, Mandy M, Griffin, W Sue T, Basile, Anthony S, Barger, Steven W

“…BACKGROUND: Roles for excitotoxicity and inflammation in Alzheimer's disease have been hypothesized. Proinflammatory stimuli, including amyloid beta-peptide…”
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A Role for P-Glycoprotein in Clearance of Alzheimer Amyloid β -Peptide from the Brain by Wang, Wei, Bodles-Brakhop, Angela M, Barger, Steven W

“…Most data indicates that Alzheimer's disease involves an accumulation of amyloid β - peptide (Aβ) in the CNS and that sporadic cases arise from a deficiency in…”
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Amyloid precursor protein modulates beta-catenin degradation by Chen, Yuzhi, Bodles, Angela M

“…The amyloid precursor protein (APP) is genetically associated with Alzheimer's disease (AD). Elucidating the function of APP should help understand AD…”
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Pioglitazone induces apoptosis of macrophages in human adipose tissue by Bodles, Angela M., Varma, Vijayalakshmi, Yao-Borengasser, Aiwei, Phanavanh, Bounleut, Peterson, Charlotte A., McGehee, Robert E., Rasouli, Neda, Wabitsch, Martin, Kern, Philip A.

“…Metabolic syndrome and type 2 diabetes mellitus are associated with an increased number of macrophage cells that infiltrate white adipose tissue (WAT)…”
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Stearoyl-Coenzyme A Desaturase 1 Gene Expression Increases after Pioglitazone Treatment and Is Associated with Peroxisomal Proliferator-Activated Receptor-γ Responsiveness by Yao-Borengasser, Aiwei, Rassouli, Negah, Varma, Vijayalakshmi, Bodles, Angela M., Rasouli, Neda, Unal, Resat, Phanavanh, Bounleut, Ranganathan, Gouri, McGehee, Robert E., Kern, Philip A.

“…Context and Objective: Stearoyl-coenzyme A desaturase (SCD1) is the rate-limiting enzyme that converts palmitoyl- and stearoyl-coenzyme A to palmitoleoyl- and…”
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Cytokines and the aging brain – what we don't know might help us by Bodles, Angela M., Barger, Steven W.

“…Cognitive aspects of aging represent a grave challenge for our societal circumstances as members of the baby-boom generation spiral toward a collective ‘senior…”
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Electroporation for the Delivery of DNA-based Vaccines and Immunotherapeutics: Current Clinical Developments by Bodles-Brakhop, Angela M, Heller, Richard, Draghia-Akli, Ruxandra

“…Electroporation (EP) has been used in basic research for the past 25 years to aid in the transfer of DNA into cells in vitro. EP in vivo enhances transfer of…”
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Secreted β-amyloid precursor protein activates microglia via JNK and p38-MAPK by Bodles, Angela M., Barger, Steven W.

“…Reactive microglia are thought to play a role in the pathogenesis of Alzheimer’s disease (AD) and are localized to the senile plaques that are associated with…”
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Gene therapy by electroporation for the treatment of chronic renal failure in companion animals by Brown, Patricia A, Bodles-Brakhop, Angela M, Pope, Melissa A, Draghia-Akli, Ruxandra

“…Growth hormone-releasing hormone (GHRH) plasmid-based therapy for the treatment of chronic renal failure and its complications was examined. Companion dogs…”
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Inhibition of fibril formation and toxicity of a fragment of α-synuclein by an N-methylated peptide analogue by Bodles, Angela M., El-Agnaf, Omar M.A., Greer, Brett, Guthrie, David J.S., Irvine, G.Brent

“…α-Synuclein has been linked to amyloidogenesis in Parkinson's disease and other neurodegenerative disorders. We have previously shown that a peptide comprising…”
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APP-BP1 inhibits A beta 42 levels by interacting with Presenilin-1 by Chen, Yuzhi, Bodles, Angela M, McPhie, Donna L, Neve, Rachael L, Mrak, Robert E, Griffin, W Sue T

“…The beta -amyloid precursor protein (APP) is sequentially cleaved by the beta - and then gamma -secretase to generate the amyloid beta -peptides A beta 40 and…”
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Calcium is involved in formation of high molecular weight adiponectin by Banga, Anannya, Bodles, Angela M, Rasouli, Neda, Ranganathan, Gouri, Kern, Philip A, Owens, Randall J

“…Adiponectin, an adipocyte-specific secretory protein, is known to circulate as different isoforms in the blood stream. Using sucrose gradients and Western…”
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DNA vaccination and gene therapy: optimization and delivery for cancer therapy by Bodles-Brakhop, Angela M, Draghia-Akli, Ruxandra

“…This review will focus on DNA vaccine approaches for the prevention or treatment of cancer and its complications. DNA vaccine therapies are a relatively novel…”
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Effects of maternal plasmid GHRH treatment on offspring growth by Khan, Amir S, Bodles-Brakhop, Angela M, Fiorotto, Marta L, Draghia-Akli, Ruxandra

“…Abstract To differentiate prenatal effects of plasmid growth hormone-releasing hormone (GHRH) treatment from maternal effects mediated by lactation on…”
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Growth Hormone–releasing Hormone Plasmid Treatment by Electroporation Decreases Offspring Mortality Over Three Pregnancies by Person, Ryan, Bodles-Brakhop, Angela M, Pope, Melissa A, Brown, Patricia A, Khan, Amir S, Draghia-Akli, Ruxandra

“…LifeTideSW5 is a growth hormone–releasing hormone (GHRH)–expressing plasmid delivered by intramuscular (IM) electroporation (EP), and the first therapeutic…”
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Double-blinded, Placebo-controlled Plasmid GHRH Trial for Cancer-associated Anemia in Dogs by Bodles-Brakhop, Angela M, Brown, Patricia A, Pope, Melissa A, Draghia-Akli, Ruxandra

“…The use of growth hormone releasing hormone (GHRH) plasmid–based therapy to treat companion dogs with spontaneous malignancies and anemia receiving a…”
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