Search Results - "Bodine, David M."

Introduction to the review series on transcription factors in hematopoiesis and hematologic disease by Bodine, David M.

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Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways by Psaila, Bethan, Barkas, Nikolaos, Iskander, Deena, Roy, Anindita, Anderson, Stacie, Ashley, Neil, Caputo, Valentina S, Lichtenberg, Jens, Loaiza, Sandra, Bodine, David M, Karadimitris, Anastasios, Mead, Adam J, Roberts, Irene

“…Recent advances in single-cell techniques have provided the opportunity to finely dissect cellular heterogeneity within populations previously defined by…”
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Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development by Paralkar, Vikram R., Mishra, Tejaswini, Luan, Jing, Yao, Yu, Kossenkov, Andrew V., Anderson, Stacie M., Dunagin, Margaret, Pimkin, Maxim, Gore, Meghneel, Sun, Diana, Konuthula, Neeraja, Raj, Arjun, An, Xiuli, Mohandas, Narla, Bodine, David M., Hardison, Ross C., Weiss, Mitchell J.

“…Mammals express thousands of long noncoding (lnc) RNAs, a few of which are known to function in tissue development. However, the entire repertoire of lncRNAs…”
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Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation by Nemeth, Michael J, Topol, Lilia, Anderson, Stacie M, Yang, Yingzi, Bodine, David M

“…The mechanisms that regulate hematopoietic stem cell (HSC) fate decisions between proliferation and multilineage differentiation are unclear. Members of the…”
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Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites by Hogart, Amber, Lichtenberg, Jens, Ajay, Subramanian S, Anderson, Stacie, Margulies, Elliott H, Bodine, David M

“…DNA methylation is an essential epigenetic mark that is required for normal development. Knockout of the DNA methyltransferase enzymes in the mouse…”
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Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development by Roy, Anindita, Wang, Guanlin, Iskander, Deena, O’Byrne, Sorcha, Elliott, Natalina, O’Sullivan, Jennifer, Buck, Gemma, Heuston, Elisabeth F., Wen, Wei Xiong, Meira, Alba Rodriguez, Hua, Peng, Karadimitris, Anastasios, Mead, Adam J., Bodine, David M., Roberts, Irene, Psaila, Bethan, Thongjuea, Supat

“…Human hematopoiesis is a dynamic process that starts in utero 18–21 days post-conception. Understanding the site- and stage-specific variation in hematopoiesis…”
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Ribosomal protein gene deletions in Diamond-Blackfan anemia by Farrar, Jason E., Vlachos, Adrianna, Atsidaftos, Eva, Carlson-Donohoe, Hannah, Markello, Thomas C., Arceci, Robert J., Ellis, Steven R., Lipton, Jeffrey M., Bodine, David M.

“…Diamond-Blackfan anemia (DBA) is a congenital BM failure syndrome characterized by hypoproliferative anemia, associated physical abnormalities, and a…”
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Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells by Glait‐Santar, Chen, Desmond, Ronan, Feng, Xingmin, Bat, Taha, Chen, Jichun, Heuston, Elisabeth, Mizukawa, Benjamin, Mulloy, James C., Bodine, David M., Larochelle, Andre, Dunbar, Cynthia E.

“…Hematopoietic stem and progenitor cells (HSPCs) reside in a specialized niche that regulates their proliferative capacity and their fate. There is increasing…”
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Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion by Anong, William A., Franco, Taina, Chu, Haiyan, Weis, Tahlia L., Devlin, Emily E., Bodine, David M., An, Xiuli, Mohandas, Narla, Low, Philip S.

“…The erythrocyte membrane skeleton is the best understood cytoskeleton. Because its protein components have homologs in virtually all other cells, the membrane…”
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Hemozoin produced by mammals confers heme tolerance by Pek, Rini H, Yuan, Xiaojing, Rietzschel, Nicole, Zhang, Jianbing, Jackson, Laurie, Nishibori, Eiji, Ribeiro, Ana, Simmons, William, Jagadeesh, Jaya, Sugimoto, Hiroshi, Alam, Md Zahidul, Garrett, Lisa, Haldar, Malay, Ralle, Martina, Phillips, John D, Bodine, David M, Hamza, Iqbal

“…Free heme is cytotoxic as exemplified by hemolytic diseases and genetic deficiencies in heme recycling and detoxifying pathways. Thus, intracellular…”
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Defective erythropoiesis caused by mutations of the thyroid hormone receptor α gene by Park, Sunmi, Han, Cho Rong, Park, Jeong Won, Zhao, Li, Zhu, Xuguang, Willingham, Mark, Bodine, David M, Cheng, Sheue-Yann

“…Patients with mutations of the THRA gene exhibit classical features of hypothyroidism, including erythroid disorders. We previously created a mutant mouse…”
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Molecular convergence in ex vivo models of Diamond-Blackfan anemia by O'Brien, Kelly A., Farrar, Jason E., Vlachos, Adrianna, Anderson, Stacie M., Tsujiura, Crystiana A., Lichtenberg, Jens, Blanc, Lionel, Atsidaftos, Eva, Elkahloun, Abdel, An, Xiuli, Ellis, Steven R., Lipton, Jeffrey M., Bodine, David M.

“…Diamond-Blackfan anemia (DBA) is a congenital bone marrow failure syndrome characterized by erythroid hypoplasia, usually without perturbation of other…”
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Hmgb3 Regulates the Balance between Hematopoietic Stem Cell Self-Renewal and Differentiation by Nemeth, Michael J., Kirby, Martha R., Bodine, David M.

“…Hmgb3 is an X-linked member of a family of sequence-independent chromatin-binding proteins that is preferentially expressed in hematopoietic stem cells (HSC)…”
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Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation by Pilon, Andre M., Ajay, Subramanian S., Kumar, Swathi Ashok, Steiner, Laurie A., Cherukuri, Praveen F., Wincovitch, Stephen, Anderson, Stacie M., Mullikin, James C., Gallagher, Patrick G., Hardison, Ross C., Margulies, Elliott H., Bodine, David M.

“…Erythropoiesis is dependent on the activity of transcription factors, including the erythroid-specific erythroid Kruppel-like factor (EKLF). ChIP followed by…”
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Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points by Heuston, Elisabeth F, Keller, Cheryl A, Lichtenberg, Jens, Giardine, Belinda, Anderson, Stacie M, Hardison, Ross C, Bodine, David M

“…Enhancers and promoters are cis-acting regulatory elements associated with lineage-specific gene expression. Previous studies showed that different categories…”
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Exploiting pre‐rRNA processing in Diamond Blackfan anemia gene discovery and diagnosis by Farrar, Jason E., Quarello, Paola, Fisher, Ross, O'Brien, Kelly A., Aspesi, Anna, Parrella, Sara, Henson, Adrianna L., Seidel, Nancy E., Atsidaftos, Eva, Prakash, Supraja, Bari, Shahla, Garelli, Emanuela, Arceci, Robert J., Dianzani, Irma, Ramenghi, Ugo, Vlachos, Adrianna, Lipton, Jeffrey M., Bodine, David M., Ellis, Steven R.

“…Diamond Blackfan anemia (DBA), a syndrome primarily characterized by anemia and physical abnormalities, is one among a group of related inherited bone marrow…”
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Anemia of inflammation is all the RAGE by Bodine, David M.

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Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome by Xi, Hualin, Shulha, Hennady P, Lin, Jane M, Vales, Teresa R, Fu, Yutao, Bodine, David M, McKay, Ronald D G, Chenoweth, Josh G, Tesar, Paul J, Furey, Terrence S, Ren, Bing, Weng, Zhiping, Crawford, Gregory E

“…The identification of regulatory elements from different cell types is necessary for understanding the mechanisms controlling cell type-specific and…”
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Regulation of hematopoiesis and the hematopoietic stem cell niche by Wnt signaling pathways by Nemeth, Michael J, Bodine, David M

“…Hematopoietic stem cells (HSCs) are a rare population of cells that are responsible for life-long generation of blood cells of all lineages. In order to…”
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Failure of Terminal Erythroid Differentiation in EKLF-Deficient Mice Is Associated with Cell Cycle Perturbation and Reduced Expression of E2F2 by Pilon, Andre M., Arcasoy, Murat O., Dressman, Holly K., Vayda, Serena E., Maksimova, Yelena D., Sangerman, Jose I., Gallagher, Patrick G., Bodine, David M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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