Search Results - "Bodi, Zsuzsanna"
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1
Identification of factors required for m6A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI
Published in The New phytologist (01-07-2017)“…N6-adenosine methylation (m6A) of mRNA is an essential process in most eukaryotes, but its role and the status of factors accompanying this modification are…”
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2
CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses
Published in Nature communications (08-03-2022)“…Cap-adjacent nucleotides of animal, protist and viral mRNAs can be O -methylated at the 2‘ position of the ribose (cOMe). The functions of cOMe in animals,…”
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3
Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging
Published in Molecular psychiatry (01-12-2021)“…Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis…”
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4
Two zinc finger proteins with functions in m6A writing interact with HAKAI
Published in Nature communications (02-03-2022)“…The methyltransferase complex (m 6 A writer), which catalyzes the deposition of N 6 -methyladenosine (m 6 A) in mRNAs, is highly conserved across most…”
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5
A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA
Published in Scientific reports (24-10-2011)“…A method is described for the detection of certain nucleotide modifications adjacent to the 5’ 7-methyl guanosine cap of mRNAs from individual genes. The…”
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6
The effect of adenosine monophosphate deaminase overexpression on the accumulation of umami-related metabolites in tomatoes
Published in Plant cell reports (01-01-2017)“…Key message This study highlights the changes in umami-related nucleotide and glutamate levels when the AMP deaminase gene was elevated in transgenic tomato…”
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7
Yeast m6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment
Published in PloS one (17-07-2015)“…Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the finding of FTO's (Fat Mass…”
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8
MTA Is an Arabidopsis Messenger RNA Adenosine Methylase and Interacts with a Homolog of a Sex-Specific Splicing Factor
Published in The Plant cell (01-05-2008)“…N⁶-Methyladenosine is a ubiquitous modification identified in the mRNA of numerous eukaryotes, where it is present within both coding and noncoding regions…”
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9
Yeast targets for mRNA methylation
Published in Nucleic acids research (01-09-2010)“…N⁶-Methyladenosine (m⁶A) is a modified base present in the mRNA of all higher eukaryotes and in Saccharomyces cerevisiae, where there is an increase in m⁶A…”
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10
Adenosine Methylation in Arabidopsis mRNA is Associated with the 3' End and Reduced Levels Cause Developmental Defects
Published in Frontiers in plant science (01-01-2012)“…We previously showed that the N6-methyladenosine (m(6)A) mRNA methylase is essential during Arabidopsis thaliana embryonic development. We also demonstrated…”
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11
Detection and Quantification of N 6 -Methyladenosine in Messenger RNA by TLC
Published in Methods in molecular biology (Clifton, N.J.) (2017)“…The base-modified nucleotide, N -methyladenosine, is a relatively abundant modification found in the mRNA of most higher eukaryotes. Methylation levels can…”
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12
mRNA adenosine methylase (MTA) deposits m 6 A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-2020)“…Significance Recently N 6 -methyladenosine (m 6 A) methylation has emerged as a biological process with significant impact on cellular functions. However,…”
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13
m^sup 6^A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination
Published in Nature (London) (08-12-2016)“…N^sup 6^-methyladenosine (m^sup 6^A) is the most common internal modification of eukaryotic messenger RNA (mRNA) and is decoded by YTH domain proteins1-7. The…”
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14
mRNA adenosine methylase (MTA) deposits m⁶A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-2020)“…In Arabidopsis thaliana, the METTL3 homolog, mRNA adenosine methylase (MTA) introduces N⁶-methyladenosine (m⁶A) into various coding and noncoding RNAs of the…”
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15
The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer
Published in Cancers (01-10-2022)“…Prostate cancer (PCa) is a leading cause of cancer-related deaths and is driven by aberrant androgen receptor (AR) signalling. For this reason, androgen…”
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16
Yeast m.sup.6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment
Published in PloS one (17-07-2015)“…Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the finding of FTO's (Fat Mass…”
Get full text
Journal Article -
17
Two zinc finger proteins with functions in m 6 A writing interact with HAKAI
Published in Nature communications (02-03-2022)“…The methyltransferase complex (m A writer), which catalyzes the deposition of N -methyladenosine (m A) in mRNAs, is highly conserved across most eukaryotic…”
Get full text
Journal Article -
18
m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination
Published in Nature (London) (08-12-2016)“…Two complementary studies describe how the pervasive N 6 -methyladenosine modification in mRNA can affect Drosophila sex determination, neuronal function and…”
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Journal Article -
19
Identification of factors required for m 6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI
Published in The New phytologist (01-07-2017)“…N6-adenosine methylation (m A) of mRNA is an essential process in most eukaryotes, but its role and the status of factors accompanying this modification are…”
Get full text
Journal Article -
20
Modifying the m 6 A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging
Published in Molecular psychiatry (01-12-2021)“…Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis…”
Get full text
Journal Article