Search Results - "Bodensieck, Antje"
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New Eremophilane Sesquiterpenes from a Rhizome Extract of Petasites hybridus
Published in Helvetica chimica acta (01-01-2007)“…A total of 21 natural products, 1–21, were isolated from a supercritical CO2 extract of the rhizomes of Petasites hybridus. Thereby, seven new eremophilane (=…”
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Absolute configuration of eremophilane sesquiterpenes from Petasites hybridus: Comparison of experimental and calculated circular dichroism spectra
Published in Chirality (New York, N.Y.) (01-03-2010)“…In‐depth conformational analyses of 10 known eremophilane (= (1S,4aR,7R,8aR)‐decahydro‐1,8a‐dimethyl‐7‐(1‐methylethyl)napththalene) sesquiterpenes, 1–10, from…”
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Lignan Derivatives from Krameria lappacea Roots Inhibit Acute Inflammation in Vivo and Pro-inflammatory Mediators in Vitro
Published in Journal of natural products (Washington, D.C.) (26-08-2011)“…The roots of Krameria lappacea are used traditionally against oropharyngeal inflammation. So far, the astringent and antimicrobial properties of its…”
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Differential and stereoselective in vitro cytotoxicity of eremophilane sesquiterpenes of Petasites hybridus rhizomes in rat hepatocytes
Published in Planta medica (01-01-2011)“…We tested two CO (2) extracts of Petasites hybridus L. rhizomes, A (rich in furanoeremophilanes) and B (rich in petasins), for IN VITRO cytotoxicity in rat…”
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Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation
Published in Bioorganic & medicinal chemistry (01-07-2009)“…A set of ten derivatives of methylhonokiol, an anti-inflammatory active biphenyl-type neolignan from Magnolia grandiflora, has been evaluated for their in…”
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Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB sub(4)-formation
Published in Bioorganic & medicinal chemistry (01-07-2009)“…A set of ten derivatives of methylhonokiol, an anti-inflammatory active biphenyl-type neolignan from Magnolia grandiflora, has been evaluated for their in…”
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Discovering COX-inhibiting constituents of Morus root bark: activity-guided versus computer-aided methods
Published in Planta medica (01-05-2005)“…The aim of this study was to compare the efficiency of two well known approaches for the discovery of the bioactive principle/s in medicinal plants, namely the…”
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Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
Published in Farmaco (Società chimica italiana : 1989) (01-04-2005)“…A series of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential human 5-LOX and COX 1 and COX-2 inhibitors structurally related to…”
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Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
Published in Farmaco (Società chimica italiana : 1989) (2005)“…A new series of potential human 5-LOX inhibitors structurally related to the 1-phenyl-3-pyrazolidinone (phenidone, 2) has been synthesized and the activity…”
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Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1 H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors
Published in Farmaco (Società chimica italiana : 1989) (2005)“…A series of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1 H-pyrazol-5-one as potential human 5-LOX and COX 1 and COX-2 inhibitors structurally related to…”
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