Search Results - "Bodduluru, Lakshmi Narendra"
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Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives
Published in Toxicology letters (04-03-2015)“…•Short account on role of chrysin in multistep carcinogenesis process.•Chemopreventive and therapeutic studies of chrysin in cell lines and animal…”
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Molecular and biochemical evidence on the protective effects of quercetin in isoproterenol‐induced acute myocardial injury in rats
Published in Journal of biochemical and molecular toxicology (01-01-2017)“…Cardioprotection represents one of the most important and realistic aspects of preventive therapy today. Quercetin, a naturally occurring dietary flavone, has…”
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Immune system: a double-edged sword in cancer
Published in Inflammation research (01-09-2013)“…Objective The objective of the review is to examine the role of innate and adaptive immune cells in cancer. Introduction Immune system functions as a host…”
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Baicalein protects isoproterenol induced myocardial ischemic injury in male Wistar rats by mitigating oxidative stress and inflammation
Published in Inflammation research (01-08-2016)“…Objective The aim of the present study was to investigate the cardioprotective effects of baicalein, main bioactive constituent from roots of Scutellaria…”
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Antioxidant and antitumor efficacy of Luteolin, a dietary flavone on benzo(a)pyrene-induced experimental lung carcinogenesis
Published in Biomedicine & pharmacotherapy (01-08-2016)“…Highlights • Chemopreventive effect of luteolin, a dietary flavone, is evaluated against B(a)P induced lung cancer. • Luteolin restored the tumor markers…”
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Preventive effect of berberine against DMBA-induced breast cancer in female Sprague Dawley rats
Published in Biomedicine & pharmacotherapy (01-08-2017)“…Highlights • Berberine exerts chemopreventive effect in DMBA induced mammary carcinogenesis. • Berberine treatment restored the lipid peroxidation and…”
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The renoprotective activity of hesperetin in cisplatin induced nephrotoxicity in rats: Molecular and biochemical evidence
Published in Biomedicine & pharmacotherapy (01-05-2017)“…Abstract Nephrotoxicity remain a major life-threatening complication in cancer patients on cisplatin chemotherapy. In this study, we investigated the…”
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Animal models of myocardial infarction: Mainstay in clinical translation
Published in Regulatory toxicology and pharmacology (01-04-2016)“…Preclinical models with high prognostic power are a prerequisite for translational research. The closer the similarity of a model to myocardial infarction…”
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Chemopreventive and therapeutic effects of nimbolide in cancer: The underlying mechanisms
Published in Toxicology in vitro (01-08-2014)“…•Cancer is a complex disease with dysregulation of multiple cell signaling pathways.•Chemoprevention is a strategy to block, reverse or retard…”
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Antiproliferative and antioxidant potential of hesperetin against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice
Published in Chemico-biological interactions (05-12-2015)“…Lung cancer is the foremost cause of cancer mortality and is a growing economic burden worldwide. Chemoprevention, employing the use of natural, dietary or…”
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Benzo(a)pyrene induced lung cancer: Role of dietary phytochemicals in chemoprevention
Published in Pharmacological reports (01-10-2015)“…Lung cancer is the major cause of overall cancer deaths, and chemoprevention is a promising strategy to control this disease. Benzo(a)pyrene [B(a)P], a…”
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Natural killer cells: The journey from puzzles in biology to treatment of cancer
Published in Cancer letters (28-02-2015)“…Highlights • Immunotherapy has transformed the treatment landscape for malignancies. • NK cells are emerging as novel treatment option for cancers. •…”
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Naringenin ameliorates inflammation and cell proliferation in benzo(a)pyrene induced pulmonary carcinogenesis by modulating CYP1A1, NFκB and PCNA expression
Published in International immunopharmacology (01-01-2016)“…Lung cancer is the major cause of cancer-related mortality and is a growing economic burden worldwide. Chemoprevention has emerged as a very effective…”
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BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway
Published in Environmental toxicology and pharmacology (01-03-2015)“…Abstract Diabetic nephropathy is a serious microvascular complication for patients associated with diabetes mellitus. Recent studies have suggested that NF-κB…”
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Chemopreventive effect of chrysin, a dietary flavone against benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice
Published in Pharmacological reports (01-04-2016)“…Chemoprevention is considered as one of the most promising and realistic approaches in the prevention of lung cancer. Chrysin, a naturally occurring dietary…”
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16
Effect of meditation on neurophysiological changes in stress mediated depression
Published in Complementary therapies in clinical practice (01-02-2014)“…Abstract Meditation is a complex mental practice involving changes in sensory perception, cognition, hormonal and autonomic activity. It is widely used in…”
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Chrysin and its emerging role in cancer drug resistance
Published in Chemico-biological interactions (05-07-2015)“…This letter illustrates the significant chemosensitizing effects of chrysin to resistance cancer cells and refers to the article on “Combination of chrysin and…”
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Targeting poly(ADP-ribose)polymerase1 in neurological diseases: A promising trove for new pharmacological interventions to enter clinical translation
Published in Neurochemistry international (01-10-2014)“…•Short introduction on poly(ADP-ribose)polymerase (PARP1) and its structural features.•Overview of PARP1 activity.•Succinct outline of various implications of…”
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Resveratrol ameliorates depressive-like behavior in repeated corticosterone-induced depression in mice
Published in Steroids (01-09-2015)“…•Depression is a chronic, multi-factorial psychiatric disorder.•Repeated CORT administration develops depression-like behavior in mice.•Resveratrol ameliorates…”
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Effects of Cleome viscosa on hyperalgesia, oxidative stress and lipid profile in STZ induced diabetic neuropathy in Wistar rats
Published in Pakistan journal of pharmaceutical sciences (01-09-2014)“…Diabetes mellitus is a severe devastating epidemic has an effect on both developing and developed countries. Diabetic neuropathy (DN) is a secondary…”
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