Search Results - "Bocklitz, Thomas"
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Chemometric analysis in Raman spectroscopy from experimental design to machine learning–based modeling
Published in Nature protocols (01-12-2021)“…Raman spectroscopy is increasingly being used in biology, forensics, diagnostics, pharmaceutics and food science applications. This growth is triggered not…”
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Deep learning a boon for biophotonics?
Published in Journal of biophotonics (01-06-2020)“…This review covers original articles using deep learning in the biophotonic field published in the last years. In these years deep learning, which is a subset…”
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3
Deep Learning for Raman Spectroscopy: A Review
Published in Analytica (01-09-2022)“…Raman spectroscopy (RS) is a spectroscopic method which indirectly measures the vibrational states within samples. This information on vibrational states can…”
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Exploring the Steps of Infrared (IR) Spectral Analysis: Pre-Processing, (Classical) Data Modelling, and Deep Learning
Published in Molecules (Basel, Switzerland) (30-09-2023)“…Infrared (IR) spectroscopy has greatly improved the ability to study biomedical samples because IR spectroscopy measures how molecules interact with infrared…”
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5
Modified PCA and PLS: Towards a better classification in Raman spectroscopy–based biological applications
Published in Journal of chemometrics (01-04-2020)“…Raman spectra of biological samples often exhibit variations originating from changes of spectrometers, measurement conditions, and cultivation conditions…”
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A Review on Data Fusion of Multidimensional Medical and Biomedical Data
Published in Molecules (Basel, Switzerland) (01-11-2022)“…Data fusion aims to provide a more accurate description of a sample than any one source of data alone. At the same time, data fusion minimizes the uncertainty…”
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7
Label‐Free Molecular Imaging of Biological Cells and Tissues by Linear and Nonlinear Raman Spectroscopic Approaches
Published in Angewandte Chemie International Edition (10-04-2017)“…Raman spectroscopy is an emerging technique in bioanalysis and imaging of biomaterials owing to its unique capability of generating spectroscopic fingerprints…”
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Artifacts and Anomalies in Raman Spectroscopy: A Review on Origins and Correction Procedures
Published in Molecules (Basel, Switzerland) (08-10-2024)“…Raman spectroscopy, renowned for its unique ability to provide a molecular fingerprint, is an invaluable tool in industry and academic research. However,…”
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Siamese Networks for Clinically Relevant Bacteria Classification Based on Raman Spectroscopy
Published in Molecules (Basel, Switzerland) (28-02-2024)“…Identifying bacterial strains is essential in microbiology for various practical applications, such as disease diagnosis and quality monitoring of food and…”
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10
Tracking heavy water (D₂O) incorporation for identifying and sorting active microbial cells
Published in Proceedings of the National Academy of Sciences - PNAS (13-01-2015)“…Microbial communities are essential to the function of virtually all ecosystems and eukaryotes, including humans. However, it is still a major challenge to…”
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11
A Review of Medical Image Registration for Different Modalities
Published in Bioengineering (Basel) (02-08-2024)“…Medical image registration has become pivotal in recent years with the integration of various imaging modalities like X-ray, ultrasound, MRI, and CT scans,…”
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Illuminating the Tiny World: A Navigation Guide for Proper Raman Studies on Microorganisms
Published in Molecules (Basel, Switzerland) (29-02-2024)“…Raman spectroscopy is an emerging method for the identification of bacteria. Nevertheless, a lot of different parameters need to be considered to establish a…”
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13
Use of polymers as wavenumber calibration standards in deep-UVRR
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-02-2023)“…[Display omitted] •Deep-UVRR needs to be standardized when developed for clinical diagnostics.•Wavenumber calibration is important for this attempt.•PEI, PET,…”
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14
A Systematic Investigation of Image Pre-Processing on Image Classification
Published in IEEE access (2024)“…AI-powered image analysis is a transformative technology with immense potential to enhance diagnostics and patient care. Accurate medical image assessment…”
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15
Feasibility studies of multimodal nonlinear endoscopy using multicore fiber bundles for remote scanning from tissue sections to bulk organs
Published in Scientific reports (23-08-2023)“…Here, we report on the development and application of a compact multi-core fiber optical probe for multimodal non-linear imaging, combining the label-free…”
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A systematic study of transfer learning for colorectal cancer detection
Published in Informatics in medicine unlocked (2023)“…With the rapid development of data science methods like deep learning, these methods have already been used into the field of healthcare and medicine. However,…”
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Multimodal Imaging Spectroscopy of Tissue
Published in Annual review of analytical chemistry (Palo Alto, Calif.) (22-07-2015)“…Advanced optical imaging technologies have experienced increased visibility in medical research, as they allow for a label-free and nondestructive…”
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18
UV-Raman Spectroscopic Identification of Fungal Spores Important for Respiratory Diseases
Published in Analytical chemistry (Washington) (07-08-2018)“…Fungal spores are one of several environmental factors responsible for causing respiratory diseases like asthma, chronic obstructive pulmonary disease (COPD),…”
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Monitoring Deuterium Uptake in Single Bacterial Cells via Two-Dimensional Raman Correlation Spectroscopy
Published in Analytical chemistry (Washington) (01-06-2021)“…Raman-stable isotope labeling using heavy water (Raman-D2O) is attracting great interest as a fast technique with various applications ranging from the…”
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Fusion of MALDI Spectrometric Imaging and Raman Spectroscopic Data for the Analysis of Biological Samples
Published in Frontiers in chemistry (16-07-2018)“…Despite of a large number of imaging techniques for the characterization of biological samples, no universal one has been reported yet. In this work, a data…”
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