Search Results - "Bockenstedt, Paula"

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome by Ali, Ramadan A., Gandhi, Alex A., Meng, He, Yalavarthi, Srilakshmi, Vreede, Andrew P., Estes, Shanea K., Palmer, Olivia R., Bockenstedt, Paula L., Pinsky, David J., Greve, Joan M., Diaz, Jose A., Kanthi, Yogendra, Knight, Jason S.

“…Potentiation of neutrophil extracellular trap (NET) release is one mechanism by which antiphospholipid antibodies (aPL Abs) effect thrombotic events in…”
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Anti–Neutrophil Extracellular Trap Antibodies and Impaired Neutrophil Extracellular Trap Degradation in Antiphospholipid Syndrome by Zuo, Yu, Yalavarthi, Srilakshmi, Gockman, Kelsey, Madison, Jacqueline A., Gudjonsson, Johann E., Kahlenberg, J. Michelle, Joseph McCune, W., Bockenstedt, Paula L., Karp, David R., Knight, Jason S.

“…Objective The release of neutrophil extracellular traps (NETs) by hyperactive neutrophils has recently been recognized to play an important role in…”
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Release of Neutrophil Extracellular Traps by Neutrophils Stimulated With Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome by Yalavarthi, Srilakshmi, Gould, Travis J., Rao, Ashish N., Mazza, Levi F., Morris, Alexandra E., Núñez‐Álvarez, Carlos, Hernández‐Ramírez, Diego, Bockenstedt, Paula L., Liaw, Patricia C., Cabral, Antonio R., Knight, Jason S.

“…Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I (β2GPI), are well known to activate endothelial cells, monocytes, and…”
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Increased Adhesive Potential of Antiphospholipid Syndrome Neutrophils Mediated by β2 Integrin Mac‐1 by Sule, Gautam, Kelley, William J., Gockman, Kelsey, Yalavarthi, Srilakshmi, Vreede, Andrew P., Banka, Alison L., Bockenstedt, Paula L., Eniola‐Adefeso, Omolola, Knight, Jason S.

“…Objective While the role of antiphospholipid antibodies in activating endothelial cells has been extensively studied, the impact of these antibodies on the…”
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Cryptic conspirators: a conversation about thrombocytopenia and antiphospholipid syndrome by Vreede, Andrew P, Bockenstedt, Paula L, McCune, W Joseph, Knight, Jason S

“…PURPOSE OF REVIEWAlthough antiphospholipid syndrome (APS) is best known for conveying increased risk of thrombotic events and pregnancy morbidity,…”
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Endothelial progenitor dysfunction associates with a type I interferon signature in primary antiphospholipid syndrome by Grenn, Robert C, Yalavarthi, Srilakshmi, Gandhi, Alex A, Kazzaz, Nayef M, Núñez-Álvarez, Carlos, Hernández-Ramírez, Diego, Cabral, Antonio R, McCune, W Joseph, Bockenstedt, Paula L, Knight, Jason S

“…Patients with antiphospholipid syndrome (APS) are at risk for subclinical endothelial injury, as well as accelerated atherosclerosis. In the related disease…”
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Antiphospholipid syndrome: an update for clinicians and scientists by Vreede, Andrew P, Bockenstedt, Paula L, Knight, Jason S

“…PURPOSE OF REVIEWAntiphospholipid syndrome (APS) is a leading acquired cause of thrombosis and pregnancy loss. Upon diagnosis (which is unlikely to be made…”
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Activated signature of antiphospholipid syndrome neutrophils reveals potential therapeutic target by Knight, Jason S, Meng, He, Coit, Patrick, Yalavarthi, Srilakshmi, Sule, Gautam, Gandhi, Alex A, Grenn, Robert C, Mazza, Levi F, Ali, Ramadan A, Renauer, Paul, Wren, Jonathan D, Bockenstedt, Paula L, Wang, Hui, Eitzman, Daniel T, Sawalha, Amr H

“…Antiphospholipid antibodies, present in one-third of lupus patients, increase the risk of thrombosis. We recently reported a key role for neutrophils -…”
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Aggressive Chronic Lymphocytic Leukemia with Elevated Genomic Complexity Is Associated with Multiple Gene Defects in the Response to DNA Double-Strand Breaks by OUILLETTE, Peter, FOSSUM, Samuel, PARKIN, Brian, LI DING, BOCKENSTEDT, Paula, AL-ZOUBI, Ammar, SHEDDEN, Kerby, MALEK, Sami N

“…Purpose: Genomic complexity is present in approximately 15% to 30% of all chronic lymphocytic leukemia (CLL) and has emerged as a strong independent predictor…”
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Thrombocytopenia in Pregnancy by Bockenstedt, Paula L., MD

“…Thrombocytopenia in pregnancy is most frequently a benign process that does not require intervention. However, 35% of cases of thrombocytopenia in pregnancy…”
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NF1 Inactivation in Adult Acute Myelogenous Leukemia by PARKIN, Brian, OUILLETTE, Peter, AL-ZOUBI, Ammar, TALPAZ, Moshe, KUJAWSKI, Lisa, YANG LIU, SHEDDEN, Kerby, SHAKHAN, Sajid, CHENG LI, ERBA, Harry, MALEK, Sami N, YIN WANG, YAN LIU, WRIGHT, Whitney, ROULSTON, Diane, PURKAYASTHA, Anjali, DRESSEL, Amanda, KARP, Judith, BOCKENSTEDT, Paula

“…This study was conducted to identify novel genes with importance to the biology of adult acute myelogenous leukemia (AML). We analyzed DNA from highly purified…”
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Comparison of characteristics from White‐ and Black‐Americans with venous thromboembolism: A cross‐sectional study by Heit, John A., Beckman, Michele G., Bockenstedt, Paula L., Grant, Althea M., Key, Nigel S., Kulkarni, Roshni, Manco‐Johnson, Marilyn J., Moll, Stephan, Ortel, Thomas L., Philipp, Claire S.

“…When compared with Whites, Black‐Americans may have a 40% higher incidence venous thromboembolism (VTE) incidence. However, whether other VTE characteristics…”
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Venous thromboembolic disease by Streiff, Michael B, Bockenstedt, Paula L, Cataland, Spero R, Chesney, Carolyn, Eby, Charles, Fanikos, John, Fogarty, Patrick F, Gao, Shuwei, Garcia-Aguilar, Julio, Goldhaber, Samuel Z, Hassoun, Hani, Hendrie, Paul, Holmstrom, Bjorn, Jones, Kimberly A, Kuderer, Nicole, Lee, Jason T, Millenson, Michael M, Neff, Anne T, Ortel, Thomas L, Smith, Judy L, Yee, Gary C, Zakarija, Anaadriana

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Differences in Thrombotic Risk Factors in Black and White Women with Adverse Pregnancy Outcome by Philipp, Claire S, Faiz, Ambarina S, Beckman, Michele G, Grant, Althea, Bockenstedt, Paula L, Heit, John A, James, Andra H, Kulkarni, Roshni, Manco-Johnson, Marilyn J, Moll, Stephan, Ortel, Thomas L

“…Abstract Introduction Black women have an increased risk of adverse pregnancy outcomes and the characteristics of thrombotic risk factors in this population…”
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Cancer-Associated Venous Thromboembolic Disease, Version 1.2015 by Streiff, Michael B, Holmstrom, Bjorn, Ashrani, Aneel, Bockenstedt, Paula L, Chesney, Carolyn, Eby, Charles, Fanikos, John, Fenninger, Randolph B, Fogerty, Annemarie E, Gao, Shuwei, Goldhaber, Samuel Z, Hendrie, Paul, Kuderer, Nicole, Lee, Alfred, Lee, Jason T, Lovrincevic, Mirjana, Millenson, Michael M, Neff, Anne T, Ortel, Thomas L, Paschal, Rita, Shattil, Sanford, Siddiqi, Tanya, Smock, Kristi J, Soff, Gerald, Wang, Tzu-Fei, Yee, Gary C, Zakarija, Anaadriana, McMillian, Nicole, Engh, Anita M

“…The NCCN Guidelines for Cancer-Associated Venous Thromboembolic Disease outline strategies for treatment and prevention of venous thromboembolism (VTE) in…”
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Management of hereditary hypercoagulable disorders by Bockenstedt, Paula L

“…The clinical management of individuals with hereditary hypercoaguable disorders has evolved from initial broad recommendations of lifelong anticoagulation…”
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Venous thromboembolic disease by Streiff, Michael B, Bockenstedt, Paula L, Cataland, Spero R, Chesney, Carolyn, Eby, Charles, Fanikos, John, Fogerty, Annemarie E, Gao, Shuwei, Goldhaber, Samuel Z, Hassoun, Hani, Hendrie, Paul, Holmstrom, Bjorn, Kuderer, Nicole, Lee, Jason T, Millenson, Michael M, Neff, Anne T, Ortel, Thomas L, Siddiqi, Tanya, Smith, Judy L, Yee, Gary C, Zakarija, Anaadriana, McMillian, Nicole, Naganuma, Maoko

“…Venous thromboembolism (VTE) remains a common and life-threatening complication among patients with cancer. Thromboprophylaxis can be used to prevent the…”
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Venous thromboembolic disease. Clinical practice guidelines in oncology by Wagman, Lawrence D, Baird, Melissa F, Bennett, Charles L, Bockenstedt, Paula L, Cataland, Spero R, Fanikos, John, Fogarty, Patrick F, Goldhaber, Samuel Z, Grover, Tejpal S, Haire, William, Hassoun, Hani, Jahanzeb, Mohammad, Leung, Lawrence L, Linenberger, Michael L, Millenson, Michael M, Ortel, Thomas L, Salem, Riad, Smith, Judy L, Streiff, Michael B

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Increased adhesive potential of antiphospholipid syndrome neutrophils mediated by beta-2 integrin Mac-1 by Sule, Gautam, Kelley, William J., Gockman, Kelsey, Yalavarthi, Srilakshmi, Vreede, Andrew P., Banka, Alison L., Bockenstedt, Paula L., Eniola-Adefeso, Omolola, Knight, Jason S.

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Ruxolitinib in adult patients with secondary haemophagocytic lymphohistiocytosis: an open-label, single-centre, pilot trial by Ahmed, Asra, Merrill, Samuel A, Alsawah, Fares, Bockenstedt, Paula, Campagnaro, Erica, Devata, Sumana, Gitlin, Scott D, Kaminski, Mark, Cusick, Alice, Phillips, Tycel, Sood, Suman, Talpaz, Moshe, Quiery, Albert, Boonstra, Philip S, Wilcox, Ryan A

“…Hemophagocytic lymphohistiocytosis is a cytokine-driven inflammatory syndrome that is associated with substantial morbidity and mortality. Overall survival in…”
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