Search Results - "Bochot, Amélie"

Thirty years with cyclodextrins by Duchêne, Dominique, Bochot, Amélie

“…[Display omitted] This paper reviews the work carried out on cyclodextrins during some thirty years at the Institut Galien Paris-Sud, UMR CNRS 8612, Université…”
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Recent advances in local drug delivery to the inner ear by El Kechai, Naila, Agnely, Florence, Mamelle, Elisabeth, Nguyen, Yann, Ferrary, Evelyne, Bochot, Amélie

“…[Display omitted] Inner ear diseases are not adequately treated by systemic drug administration mainly because of the blood–perilymph barrier that reduces…”
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Extracellular Vesicles and Biomaterial Design: New Therapies for Cardiac Repair by Pezzana, Chloé, Agnely, Florence, Bochot, Amélie, Siepmann, Juergen, Menasché, Philippe

“…There is increasing evidence that extracellular vesicles (EVs) mediate the paracrine effects of stem cells. Although EVs have several attractive…”
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Nanocarriers for drug delivery to the inner ear: Physicochemical key parameters, biodistribution, safety and efficacy by Jaudoin, Céline, Agnely, Florence, Nguyen, Yann, Ferrary, Evelyne, Bochot, Amélie

“…[Display omitted] Despite the high incidence of inner ear disorders, there are still no dedicated medications on the market. Drugs are currently administered…”
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Effect of liposomes on rheological and syringeability properties of hyaluronic acid hydrogels intended for local injection of drugs by El Kechai, Naila, Bochot, Amélie, Huang, Nicolas, Nguyen, Yann, Ferrary, Evelyne, Agnely, Florence

“…[Display omitted] The aim of this work was to thoroughly study the effect of liposomes on the rheological and the syringeability properties of hyaluronic acid…”
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Ocular delivery of nucleic acids: antisense oligonucleotides, aptamers and siRNA by Fattal, Elias, Bochot, Amélie

“…Nucleic acids have gained a lot of interest for the treatment of ocular diseases. The first to enter in clinic has been Vitravene ® an antisense…”
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Liposomes for intravitreal drug delivery: A state of the art by Bochot, Amélie, Fattal, Elias

“…Intravitreal administration of drugs has raised a large interest during the last two decades improving the treatment of infectious diseases of the posterior…”
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Controlled delivery of follicle-stimulating hormone in cattle by Deguettes, Quentin, Fattal, Elias, Moreau, Marinette, Lego, Elodie, Bochot, Amélie

“…[Display omitted] •Embryo transfer in cattle using superovulation is an important process.•Several intramuscular injections of follicle-stimulating hormone are…”
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State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers by Fattal, Elias, Bochot, Amélie

“…Knocking down gene expression using either antisense oligonucleotides (AS-ODNs) or small interfering RNA (siRNAs) has raised a lot of interest in designing new…”
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Influence of polymer behaviour in organic solution on the production of polylactide nanoparticles by nanoprecipitation by Legrand, Philippe, Lesieur, Sylviane, Bochot, Amélie, Gref, Ruxandra, Raatjes, Wouter, Barratt, Gillian, Vauthier, Christine

“…The aim of this study was to define the parameters determining an optimized yield of monodisperse, nanosized particles after nanoprecipitation of a…”
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Hybrid systems combining liposomes and entangled hyaluronic acid chains: Influence of liposome surface and drug encapsulation on the microstructure by Jaudoin, Céline, Grillo, Isabelle, Cousin, Fabrice, Gehrke, Maria, Ouldali, Malika, Arteni, Ana-Andreea, Picton, Luc, Rihouey, Christophe, Simelière, Fanny, Bochot, Amélie, Agnely, Florence

“…[Display omitted] Mixtures of hyaluronic acid (HA) with liposomes lead to hybrid colloid–polymer systems with a great interest in drug delivery. However,…”
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Transtympanic injection of a liposomal gel loaded with N-acetyl-L-cysteine: A relevant strategy to prevent damage induced by cochlear implantation in guinea pigs? by Jaudoin, Céline, Carré, Fabienne, Gehrke, Maria, Sogaldi, Audrey, Steinmetz, Vincent, Hue, Nathalie, Cailleau, Catherine, Tourrel, Guillaume, Nguyen, Yann, Ferrary, Evelyne, Agnely, Florence, Bochot, Amélie

“…[Display omitted] Patients with residual hearing can benefit from cochlear implantation. However, insertion can damage cochlear structures and generate…”
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Biomaterial-embedded extracellular vesicles improve recovery of the dysfunctional myocardium by Pezzana, Chloé, Cras, Audrey, Simelière, Fanny, Guesdon, Rose, Desgres, Manon, Correa, Bruna Lima, Peuffier, Ashley, Bellamy, Valérie, Gouarderes, Sara, Alberdi, Antonio, Perier, Marie-Cécile, Pidial, Laetitia, Agnely, Florence, Bochot, Amélie, Hagège, Albert, Silvestre, Jean-Sébastien, Menasché, Philippe

“…Extracellular vesicles (EV) are increasingly recognized as a therapeutic option in heart failure. They are usually administered by direct intramyocardial…”
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Hyaluronic acid liposomal gel sustains delivery of a corticoid to the inner ear by El Kechai, Naila, Mamelle, Elisabeth, Nguyen, Yann, Huang, Nicolas, Nicolas, Valérie, Chaminade, Pierre, Yen-Nicolaÿ, Stéphanie, Gueutin, Claire, Granger, Benjamin, Ferrary, Evelyne, Agnely, Florence, Bochot, Amélie

“…The inner ear is one of the most challenging organs for drug delivery, mainly because of the blood-perilymph barrier. Therefore, local rather than systemic…”
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Mixtures of hyaluronic acid and liposomes for drug delivery: Phase behavior, microstructure and mobility of liposomes by El Kechai, Naila, Geiger, Sandrine, Fallacara, Arianna, Cañero Infante, Ingrid, Nicolas, Valérie, Ferrary, Evelyne, Huang, Nicolas, Bochot, Amélie, Agnely, Florence

“…[Display omitted] Hyaluronic acid liposomal gels have previously demonstrated in vivo their great potential for drug delivery. Elucidating their phase behavior…”
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An injectable, nanostructured implant for the delivery of adenosine triphosphate: towards long-acting formulations of small, hydrophilic drugs by Giacalone, Giovanna, Quaillet, Marion, Huang, Nicolas, Nicolas, Valérie, Boulogne, Claire, Gillet, Cynthia, Fattal, Elias, Bochot, Amélie, Hillaireau, Hervé

“…While long-acting injectable treatments are gaining increasing interest in managing chronic diseases, the available drug delivery systems almost exclusively…”
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Hyaluronic acid-bearing lipoplexes: Physico-chemical characterization and in vitro targeting of the CD44 receptor by Dufaÿ Wojcicki, Amélie, Hillaireau, Hervé, Nascimento, Thais Leite, Arpicco, Silvia, Taverna, Myriam, Ribes, Sandy, Bourge, Mickaël, Nicolas, Valérie, Bochot, Amélie, Vauthier, Christine, Tsapis, Nicolas, Fattal, Elias

“…The mechanism by which hyaluronic acid (HA)-bearing lipoplexes target the A549 lung cancer cell line was evaluated. For this purpose, cationic liposomes…”
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Encapsulation of dexamethasone into biodegradable polymeric nanoparticles by Gómez-Gaete, Carolina, Tsapis, Nicolas, Besnard, Madeleine, Bochot, Amélie, Fattal, Elias

“…The present paper concerns both the optimization of dexamethasone (DXM) entrapment and its release from biodegradable poly( d, l-lactide- co-glycolide) (PLGA)…”
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Assessment of the efficacy of a local steroid rescue treatment administered 2 days after a moderate noise-induced trauma in guinea pig by Mamelle, Elisabeth, El Kechai, Naila, Adenis, Victor, Nguyen, Yann, Sterkers, Olivier, Agnely, Florence, Bochot, Amélie, Edeline, Jean Marc, Ferrary, Evelyne

“…Intratympanic injection of corticosteroids membrane after noise-induced hearing loss is an accepted alternative to general administration. We investigated the…”
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Effect of a liposomal hyaluronic acid gel loaded with dexamethasone in a guinea pig model after manual or motorized cochlear implantation by Mamelle, Elisabeth, Kechai, Naila El, Granger, Benjamin, Sterkers, Olivier, Bochot, Amélie, Agnely, Florence, Ferrary, Evelyne, Nguyen, Yann

“…Goals of cochlear implantation have shifted from complete insertion of the cochlear electrode array towards low traumatic insertion with minimally invasive…”
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