Search Results - "Bochen, Florian"

Virulence function of the Ustilago maydis sterol carrier protein 2 by Krombach, Sina, Reissmann, Stefanie, Kreibich, Saskia, Bochen, Florian, Kahmann, Regine

“…The peroxisomal sterol carrier protein 2 (Scp2) of the biotrophic maize pathogen Ustilago maydis was detected in apoplastic fluid, suggesting that it might…”
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A Simple and Fast Method for the Formation and Downstream Processing of Cancer-Cell-Derived 3D Spheroids: An Example Using Nicotine-Treated A549 Lung Cancer 3D Spheres by Papapostolou, Irida, Bochen, Florian, Peinelt, Christine, Maldifassi, Maria Constanza

“…Although 2D in vitro cancer cell cultures have been used for decades as a first line-of-research tool to investigate antitumoral drugs and treatments, their…”
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Contribution of the α5 nAChR Subunit and α5SNP to Nicotine-Induced Proliferation and Migration of Human Cancer Cells by Papapostolou, Irida, Ross-Kaschitza, Daniela, Bochen, Florian, Peinelt, Christine, Maldifassi, Maria Constanza

“…Nicotine in tobacco is known to induce tumor-promoting effects and cause chemotherapy resistance through the activation of nicotinic acetylcholine receptors…”
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Antagonizing Sec62 function in intracellular Ca2+ homeostasis represents a novel therapeutic strategy for head and neck cancer by Körner, Sandrina, Pick, Tillman, Bochen, Florian, Wemmert, Silke, Körbel, Christina, Menger, Michael D., Cavalié, Adolfo, Kühn, Jan-Philipp, Schick, Bernhard, Linxweiler, Maximilian

“…Various cancer types including head and neck squamous cell carcinomas (HNSCC) show a frequent amplification of chromosomal region 3q26 that encodes, among…”
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Vitamin D deficiency in head and neck cancer patients - prevalence, prognostic value and impact on immune function by Bochen, Florian, Balensiefer, Benedikt, Körner, Sandrina, Bittenbring, Jörg Thomas, Neumann, Frank, Koch, Armand, Bumm, Klaus, Marx, Anke, Wemmert, Silke, Papaspyrou, Georgios, Zuschlag, David, Kühn, Jan Philipp, Al Kadah, Basel, Schick, Bernhard, Linxweiler, Maximilian

“…Vitamin D deficiency is frequently observed in human cancer patients and a prognostic relevance could be shown for some entities. Additionally, it is known…”
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Targeting Ion Channel TRPM4 by Preti, Barbara, Rougier, Jean-Sébastien, Papapostolou, Irida, Bochen, Florian, Gerber, Christian E, Abriel, Hugues, Lochner, Martin, Peinelt, Christine

“…The transient receptor potential melastatin 4 (TRPM4) ion channel is ubiquitously expressed. Dysregulation and/or functional mutations of TRPM4 lead to several…”
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Complexity and Specificity of Sec61-Channelopathies: Human Diseases Affecting Gating of the Sec61 Complex by Sicking, Mark, Lang, Sven, Bochen, Florian, Roos, Andreas, Drenth, Joost P H, Zakaria, Muhammad, Zimmermann, Richard, Linxweiler, Maximilian

“…The rough endoplasmic reticulum (ER) of nucleated human cells has crucial functions in protein biogenesis, calcium (Ca ) homeostasis, and signal transduction…”
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Podoplanin expression in lymph node metastases of head and neck cancer and cancer of unknown primary patients by Kühn, Jan Philipp, Bochen, Florian, Körner, Sandrina, Schick, Bernhard, Wagner, Mathias, Smola, Sigrun, Berkó-Göttel, Barbara, Morris, Luc G.T., Wang, Jingming, Bozzato, Alessandro, Linxweiler, Maximilian

“…Introduction Head and neck squamous cell carcinomas (HNSCCs) are cancers with generally poor prognosis. Outcomes have not improved in decades, with more than…”
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Augmented reality‐enhanced navigation in endoscopic sinus surgery: A prospective, randomized, controlled clinical trial by Linxweiler, Maximilian, Pillong, Lukas, Kopanja, Dragan, Kühn, Jan P., Wagenpfeil, Stefan, Radosa, Julia C., Wang, Jingming, Morris, Luc G. T., Al Kadah, Basel, Bochen, Florian, Körner, Sandrina, Schick, Bernhard

“…Objective Endoscopic sinus surgery represents the gold standard for surgical treatment of chronic sinus diseases. Thereby, navigation systems can be of…”
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Treatment of SEC62 over-expressing tumors by Thapsigargin and Trifluoperazine by Körbel, Christina, Linxweiler, Maximilian, Bochen, Florian, Wemmert, Silke, Schick, Bernhard, Meyer, Markus, Maurer, Hans, Menger, Michael D, Zimmermann, Richard, Greiner, Markus

“…Treatment with analogues of the SERCA-inhibitor Thapsigargin is a promising new approach for a wide variety of cancer entities. However, our previous studies…”
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VITAMIN D IN HEAD AND NECK CANCER by Linxweiler, Maximilian, Bochen, Florian, Koerner, Sandrina, Al Kadah, Basel, Schick, Bernhard

“…Background/Aim: Low Vitamin D serum levels are highly frequent in cancer patients and a prognostic relevance was shown for several cancer entities…”
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Abstract P1-10-28: Role of Sec62 in prediction of response to neoadjuvant chemotherapy in patients with primary breast cancer by Radosa, Julia Caroline, Kasoha, Mariz, Doerk, Merle, Linxweiler, Barbara, Linxweiler, Maximilian, Bochen, Florian, Bohle, Rainer M, Wagner, Matthias, Radosa, Marc P, Solomayer, Erich-Franz, Takacs, Zoltan Ferenc

“…Abstract Background Chromosome 3q26 amplifications have been shown to represent a frequent alteration in various cancer entities including breast cancer. SEC62…”
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Characterization of miR-146a and miR-155 in blood, tissue and cell lines of head and neck squamous cell carcinoma patients and their impact on cell proliferation and migration by Lerner, Cornelia, Wemmert, Silke, Bochen, Florian, Kulas, Philipp, Linxweiler, Maximilian, Hasenfus, Andrea, Heinzelmann, Joana, Leidinger, Petra, Backes, Christina, Meese, Eckart, Urbschat, Steffi, Schick, Bernhard

“…Purpose Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignancies worldwide with an unchanged 5-year survival rate during the last…”
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Combinational chromosomal aneuploidies and HPV status for prediction of head and neck squamous cell carcinoma prognosis in biopsies and cytological preparations by Wemmert, Silke, Linxweiler, Maximilian, Lerner, Cornelia, Bochen, Florian, Kulas, Philipp, Linxweiler, Johannes, Smola, Sigrun, Urbschat, Steffi, Wagenpfeil, Stefan, Schick, Bernhard

“…Purpose Head and neck squamous cell carcinoma (HNSCC) is one of the most common human cancer types with a very poor prognosis despite improvements in…”
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Identification of SEC62 as a potential marker for 3q amplification and cellular migration in dysplastic cervical lesions by Linxweiler, Maximilian, Bochen, Florian, Schick, Bernhard, Wemmert, Silke, Al Kadah, Basel, Greiner, Markus, Hasenfus, Andrea, Bohle, Rainer-Maria, Juhasz-Böss, Ingolf, Solomayer, Erich-Franz, Takacs, Zoltan Ferenc

“…Chromosome 3 amplification affecting the 3q26 region is a common genomic alteration in cervical cancer, typically marking the transition of precancerous…”
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HPV Status as Prognostic Biomarker in Head and Neck Cancer-Which Method Fits the Best for Outcome Prediction? by Kühn, Jan Philipp, Schmid, Wendelin, Körner, Sandrina, Bochen, Florian, Wemmert, Silke, Rimbach, Hugo, Smola, Sigrun, Radosa, Julia Caroline, Wagner, Mathias, Morris, Luc G T, Bozzato, Victoria, Bozzato, Alessandro, Schick, Bernhard, Linxweiler, Maximilian

“…The incidence of human papillomavirus (HPV)-related head and neck cancer (HNSCC) is rising globally, presenting challenges for optimized clinical management…”
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Expression of SEC62 Oncogene in Benign, Malignant and Borderline Melanocytic Tumors-Unmasking the Wolf in Sheep's Clothing? by Müller, Cornelia S L, Pföhler, Claudia, Wahl, Maria, Bochen, Florian, Körner, Sandrina, Kühn, Jan Philipp, Bozzato, Alessandro, Schick, Bernhard, Linxweiler, Maximilian

“…oncogene located at chromosomal region 3q26 encodes for a transmembrane protein of the endoplasmic reticulum (ER) and is expressed at high levels in numerous…”
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Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas by Bochen, Florian, Adisurya, Hana, Wemmert, Silke, Lerner, Cornelia, Greiner, Markus, Zimmermann, Richard, Hasenfus, Andrea, Wagner, Mathias, Smola, Sigrun, Pfuhl, Thorsten, Bozzato, Alessandro, Al Kadah, Basel, Schick, Bernhard, Linxweiler, Maximilian

“…Chromosome 3q26 amplification represents a frequent alteration in head and neck squamous cell carcinomas (HNSCCs). Overexpression of 3q26 encoded genes SEC62…”
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Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum by Schorr, Stefan, Klein, Marie-Christine, Gamayun, Igor, Melnyk, Armin, Jung, Martin, Schäuble, Nico, Wang, Qian, Hemmis, Birgit, Bochen, Florian, Greiner, Markus, Lampel, Pavel, Urban, Sabine Katharina, Hassdenteufel, Sarah, Dudek, Johanna, Chen, Xing-Zhen, Wagner, Richard, Cavalié, Adolfo, Zimmermann, Richard

“…In mammalian cells, signal peptide-dependent protein transport into the endoplasmic reticulum (ER) is mediated by a dynamic polypeptide-conducting channel, the…”
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Identification of 3q oncogene SEC62 as a marker for distant metastasis and poor clinical outcome in invasive ductal breast cancer by Takacs, Ferenc Zoltan, Radosa, Julia Caroline, Linxweiler, Maximilian, Kasoha, Mariz, Bohle, Rainer M., Bochen, Florian, Unger, Clara, Solomayer, Erich-Franz, Schick, Bernard, Juhasz-Böss, Ingolf

“…Purpose In previous studies, we have shown that SEC62 has an essential function in cell migration, epithelial-to-mesenchymal transition, and endoplasmic…”
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