Search Results - "Bocckino, S B"

Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism by Bocckino, S B, Blackmore, P F, Wilson, P B, Exton, J H

“…Isolated rat hepatocytes responded to a variety of Ca2+-mobilizing agents (vasopressin, angiotensin II, epinephrine, epidermal growth factor, ATP, and ADP)…”
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Phosphatidate-Dependent Protein Phosphorylation by Bocckino, Stephen B., Wilson, Pamela B., Exton, John H.

“…Phosphatidate-dependent protein phosphorylation was observed in soluble extracts from rat liver, brain, lung, and testis. The phosphorylation was stimulated by…”
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Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II by Bocckino, S B, Blackmore, P F, Exton, J H

“…1,2-Diacylglycerol (DAG) was measured in neutral lipid extracts from isolated hepatocytes using high pressure liquid chromatography followed by refractive…”
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Hormonal stimulation of diacylglycerol formation in hepatocytes. Evidence for phosphatidylcholine breakdown by AUGERT, G, BOCCKINO, S. B, BLACKMORE, P. F, EXTON, J. H

“…The molecular species of 1,2-diacylglycerol in control and agonist-stimulated rat hepatocytes were analyzed by high performance liquid chromatography. Twelve…”
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Activation of Phospholipase D by the Fucose-Sulfate Glycoconjugate That Induces An Acrosome Reaction in Spermatozoa by Domino, S E, Bocckino, S B, Garbers, D L

“…We report for the first time that phospholipase D activity in sea urchin spermatozoa can be regulated by a component of egg jelly known to induce an acrosome…”
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Role of a guanine nucleotide-binding regulatory protein in the hydrolysis of hepatocyte phosphatidylinositol 4,5-bisphosphate by calcium-mobilizing hormones and the control of cell calcium. Studies utilizing aluminum fluoride by Blackmore, P F, Bocckino, S B, Waynick, L E, Exton, J H

“…Treatment of isolated hepatocytes with NaF produced a concentration-dependent activation of phosphorylase, inactivation of glycogen synthase, efflux of Ca2+,…”
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Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate by Lynch, C J, Charest, R, Bocckino, S B, Exton, J H, Blackmore, P F

“…Treatment of isolated hepatocytes with the tumor-promoting agent, 4 beta-phorbol 12 beta-myristate 13 alpha-acetate (PMA) produced a time- and dose-dependent,…”
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Cell signalling through phospholipid breakdown by EXTON, J. H, TAYLOR, S. J, AUGERT, G, BOCCKINO, S. B

“…There is much evidence that G-proteins transduce the signal from receptors for Ca(2+)-mobilizing agonists to the phospholipase C that catalyzes the hydrolysis…”
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Regulation of phosphatidic acid phosphohydrolase activity during stimulation of human polymorphonuclear leukocytes by Truett, 3rd, A P, Bocckino, S B, Murray, J J

“…Phosphatidic acid phosphohydrolase (PPH) activity was determined in human polymorphonuclear leukocytes (PMNs) by measuring the hydrolysis of [32P]phosphatidic…”
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Identification of a Ca2+ requirement for protein synthesis in eukaryotic cells by Brostrom, C O, Bocckino, S B, Brostrom, M A

“…The incorporation of methionine, lysine, and leucine into protein was studied in Ca2+-depleted and Ca2+-restored preparations of C-6 glial tumor cells in…”
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Regulation of protein synthesis in isolated hepatocytes by calcium-mobilizing hormones by Brostrom, C O, Bocckino, S B, Brostrom, M A, Galuska, E M

“…The incorporation of leucine into protein was studied in Ca2+-depleted and Ca2+-restored preparations of normal liver cells isolated from fed, adult male rats…”
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Perturbation of the Human T-Cell Antigen Receptor-T3 Complex Leads to the Production of Inositol Tetrakisphosphate: Evidence for Conversion from Inositol Trisphosphate by Stewart, Stanford J., Prpic, Veronica, Powers, Frances S., Bocckino, Stephen B., Isaacks, Russell E., Exton, John H.

“…Antibodies directed against the T-cell antigen receptor-T3 complex mimic antigen and lead to cellular changes consistent with activation. When cells of the…”
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Calcium-mobilizing hormones and phorbol myristate acetate mediate heterologous desensitization of the hormone-sensitive hepatic Na+/K+ pump by Lynch, C J, Bocckino, S B, Blackmore, P F, Exton, J H

“…The Na+/K+ pump in rat hepatocytes is stimulated in response to Ca2+-mobilizing hormones such as [arginine]vasopressin (AVP), angiotensin II and adrenaline, as…”
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An early elevation of diacylglycerol and phosphatidate in regenerating liver by Bocckino, S B, Wilson, P B, Exton, J H

“…Liver diacylglycerol and phosphatidate are elevated following partial hepatectomy. These increases precede those in DNA synthesis and triacylglycerol…”
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An enzymatic assay for picomole levels of phosphatidate by Bocckino, S B, Wilson, P, Exton, J H

“…An assay for phosphatidate that is sensitive, specific, and highly reproducible is described. Phosphatidate is transacylated with methylamine and the glycerol…”
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Quantification of diradylglycerols: a reply by Borchardt, R A, Bishop, W R, Bocckino, S B, Loomis, C R, Roben, D M, Ramer, J K, Van Veldhoven, P P, Bell, R M

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Inhibition of hepatic α1-adrenergic effects and binding by phorbol myristate acetate by LYNCH, C. J, CHAREST, R, BOCCKINO, S. B, EXTON, J. H, BLACKMORE, P. F

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Alterations in protein kinase C isozymes alpha and beta 2 in activated Ha-ras containing papillomas in the absence of an increase in diacylglycerol by Mills, K J, Bocckino, S B, Burns, D J, Loomis, C R, Smart, R C

“…The levels of protein kinase C (PKC) activity, PKC isozymes, as well as the level of endogenous diacylglycerols (DAG) were examined in early emergence mouse…”
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Regulation of phosphoinositide and phosphatidylcholine phospholipases by G proteins by Exton, J H, Taylor, S J, Blank, J S, Bocckino, S B

“…Two G proteins that regulate phosphoinositide phospholipase C in liver plasma membranes have been purified to homogeneity in both the heterotrimeric and…”
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Hormonal stimulation of diacylglycerol formation in hepatocytes by Augert, G, Bocckino, S B, Blackmore, P F, Exton, J H

“…The molecular species of 1,2-diacylglycerol in control and agonist-stimulated rat hepatocytes were analyzed by high performance liquid chromatography. Twelve…”
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