New procedure to fortify fluid milk with iron: Metabolic and biochemical study in rats

A comparative study with two groups of 25 rats each was undertaken in order to study fluid milk fortified with SFE-171 (stabilized FeSO 4 by micro encapsulation with phospholipids) or FeSO 4, both labeled with 59Fe. After the administration of either product, its total absorption, biodistribution an...

Full description

Saved in:

Bibliographic Details
Published in:	Nutrition research (New York, N.Y.) Vol. 16; no. 1; pp. 131 - 137
Main Authors:	Zubillaga, Marcela B., Caro, Ricardo A., Boccio, JoséR., Gotelli, Carlos A., Gotelli, Mariano J., Weill, Ricardo
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 1996 Elsevier Science
Subjects:	ABSORCION ABSORCION DE SUSTANCIAS NUTRITIVAS ABSORCION DIGESTIVA ABSORPTION ABSORPTION DE SUBSTANCES NUTRITIVES ABSORPTION DIGESTIVE BAZO Biological and medical sciences CIRCULACION SANGUINEA CIRCULATION SANGUINE COMPLEMENT ALIMENTAIRE DIETA ERITROCITOS ERYTHROCYTE FER Ferrous sulfate FOIE Food industries Fortification Fundamental and applied biological sciences. Psychology HEMOGLOBINA HEMOGLOBINE HIERRO HIGADO HUESOS INSTRUMENT DE MESURE INSTRUMENTOS DE MEDICION INTESTIN INTESTINOS Iron LAIT LECHE Metabolism METABOLISME METABOLISMO Milk Milk and cheese industries. Ice creams NUTRIENTES NUTRIENTES MINERALES PORFIRINAS PORPHYRINE PROCESAMIENTO RAT RATA RATE Rats REGIME ALIMENTAIRE REIN RINONES SANG SANGRE SUBSTANCE NUTRITIVE SUBSTANCE NUTRITIVE MINERALE SUPLEMENTOS TRAITEMENT TRANSPORT DES SUBSTANCES NUTRITIVES TRANSPORTE DE NUTRIENTES VIA BIOQUIMICA DEL METABOLISMO VOIE BIOCHIMIQUE DU METABOLISME Rats Iron Ferrous sulfate Metabolism Fortification Milk Encapsulation Pasteurized milk Nutrition Rat Rodentia Gut Dairy product Phospholipid Bioavailability Inorganic element Fortified product Vertebrata Mammalia Absorption Iron Sulfates
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	A comparative study with two groups of 25 rats each was undertaken in order to study fluid milk fortified with SFE-171 (stabilized FeSO 4 by micro encapsulation with phospholipids) or FeSO 4, both labeled with 59Fe. After the administration of either product, its total absorption, biodistribution and incorporation of iron into hemoglobin was determined for both cases. In the first case the total absorption was (28.3 ± 6.0)%, whereas in the second it was (24.1 ± 5.8)%, the difference between both values is statistically significant with a P < 0.01. The biodistribution results show that the iron from SFE-171 follows the same metabolic pathway than that from FeSO 4. The highest amount (approximately 80%) was found in blood, followed by the liver with approximately 11% and bones with a proportion somewhat higher than 4%, the activity in intestine was minimal in both cases. The 59Fe in blood was found 18 days after the administration of either product at a 100% in the red blood cells, which implies that the iron administered in the milk fortified with SFE-171 or with FeSO 4 was incorporated into hemoglobin. These results indicate with a high degree of significance that the fortification of milk with SFE-171 is a procedure which assures the effective absorption of iron and a physiological behavior of this element.
Bibliography:	S20 9705827 Q02
ISSN:	0271-5317 1879-0739
DOI:	10.1016/0271-5317(95)02067-5